DOI: 10.1093/genetics/86.2.275. MUTATIONS CAUSING TRANSFORMATION OF SEXUAL PHENOTYPE IN THE NEMATODE <i>CAENORHABDITIS ELEGANS</i>

MUTATIONS CAUSING TRANSFORMATION OF SEXUAL PHENOTYPE IN THE NEMATODE CAENORHABDITIS ELEGANS

10.1093/genetics/86.2.275

Crossref journal-article

Oxford University Press (OUP)

Genetics (286)

Abstract

ABSTRACT Ten mutations are described that transform genotypic hermaphrodites of the nematode Caenorhabditis elegans into phenotypic males. These fall into three autosomal complementation groups, termed tra-1, tra-2, and tra-3. Two alleles of tra-1 produce almost complete transformation, to a fertile male phenotype; such transformed animals are useful for analyzing sex-linked genes. All alleles of tra-1 and tra-2 are recessive; the one known allele of tra-3 is both recessive and maternal in effect. Where tested, both XX and XXX hermaphrodites are transformed into males, but XO males (true males) are unaffected by these mutations. It is suggested that these genes are actually involved in hermaphrodite development and have no role in male development.

Bibliography

Hodgkin, J. A., & Brenner, S. (1977). MUTATIONS CAUSING TRANSFORMATION OF SEXUAL PHENOTYPE IN THE NEMATODE CAENORHABDITIS ELEGANS. Genetics, 86(2), 275â287.

Authors 2

Jonathan A Hodgkin (first)
Sydney Brenner (additional)

References 0 Referenced 183

None

Dates

Type	When
Created	4 years, 4 months ago (April 21, 2021, 3:51 a.m.)
Deposited	4 years, 4 months ago (April 21, 2021, 3:51 a.m.)
Indexed	1 week, 1 day ago (Aug. 22, 2025, 1:05 a.m.)
Issued	48 years, 2 months ago (June 1, 1977)
Published	48 years, 2 months ago (June 1, 1977)
Published Online	48 years, 2 months ago (June 1, 1977)
Published Print	48 years, 2 months ago (June 1, 1977)

Funders 0

None

BibTeX

@article{Hodgkin_1977, title={MUTATIONS CAUSING TRANSFORMATION OF SEXUAL PHENOTYPE IN THE NEMATODE CAENORHABDITIS ELEGANS}, volume={86}, ISSN={1943-2631}, url={http://dx.doi.org/10.1093/genetics/86.2.275}, DOI={10.1093/genetics/86.2.275}, number={2}, journal={Genetics}, publisher={Oxford University Press (OUP)}, author={Hodgkin, Jonathan A and Brenner, Sydney}, year={1977}, month=jun, pages={275–287} }

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