DOI: 10.1093/genetics/139.1.457. A measure of population subdivision based on microsatellite allele frequencies.

A measure of population subdivision based on microsatellite allele frequencies.

10.1093/genetics/139.1.457

Crossref journal-article

Oxford University Press (OUP)

Genetics (286)

Abstract

Abstract A new measure of the extent of population subdivision as inferred from allele frequencies at microsatellite loci is proposed and tested with computer simulations. This measure, called R(ST), is analogous to Wright's F(ST) in representing the proportion of variation between populations. It differs in taking explicit account of the mutation process at microsatellite loci, for which a generalized stepwise mutation model appears appropriate. Simulations of subdivided populations were carried out to test the performance of R(ST) and F(ST). It was found that, under the generalized stepwise mutation model, R(ST) provides relatively unbiased estimates of migration rates and times of population divergence while F(ST) tends to show too much population similarity, particularly when migration rates are low or divergence times are long [corrected].

Bibliography

Slatkin, M. (1995). A measure of population subdivision based on microsatellite allele frequencies. Genetics, 139(1), 457â462.

Authors 1

M Slatkin (first)

References 0 Referenced 2,626

None

Dates

Type	When
Created	4 years, 7 months ago (Jan. 13, 2021, 4:11 p.m.)
Deposited	4 years, 4 months ago (April 22, 2021, 3:35 p.m.)
Indexed	3 days, 14 hours ago (Sept. 2, 2025, 6:56 a.m.)
Issued	30 years, 8 months ago (Jan. 1, 1995)
Published	30 years, 8 months ago (Jan. 1, 1995)
Published Online	30 years, 8 months ago (Jan. 1, 1995)
Published Print	30 years, 8 months ago (Jan. 1, 1995)

Funders 0

None

BibTeX

@article{Slatkin_1995, title={A measure of population subdivision based on microsatellite allele frequencies.}, volume={139}, ISSN={1943-2631}, url={http://dx.doi.org/10.1093/genetics/139.1.457}, DOI={10.1093/genetics/139.1.457}, number={1}, journal={Genetics}, publisher={Oxford University Press (OUP)}, author={Slatkin, M}, year={1995}, month=jan, pages={457–462} }

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