DOI: 10.1093/genetics/128.4.717. Genetic analysis of a meiotic recombination hotspot on chromosome III of Saccharomyces cerevisiae.

Genetic analysis of a meiotic recombination hotspot on chromosome III of Saccharomyces cerevisiae.

10.1093/genetics/128.4.717

Crossref journal-article

Oxford University Press (OUP)

Genetics (286)

Abstract

Abstract In a previous study, we analyzed meiotic recombination events that occurred in the 22-kb region (LEU2 to CEN3) of chromosome III of Saccharomyces cerevisiae. We found one region with an enhanced level of crossovers (a hotspot) and one region with a depressed level of crossovers. In this study, we show that about one-third of the crossovers that occur between LEU2 and CEN3 are initiated in a 1.3-kb region located approximately 6 kb from the centromere. Both crossovers and gene conversion events are initiated at this site. Events initiated at this position can be resolved as crossovers in regions located either centromere-distally or centromere-proximally from the initiation site.

Bibliography

Symington, L. S., Brown, A., Oliver, S. G., Greenwell, P., & Petes, T. D. (1991). Genetic analysis of a meiotic recombination hotspot on chromosome III of Saccharomyces cerevisiae. Genetics, 128(4), 717â727.

Authors 5

L S Symington (first)
A Brown (additional)
S G Oliver (additional)
P Greenwell (additional)
T D Petes (additional)

References 0 Referenced 20

None

Dates

Type	When
Created	4 years, 7 months ago (Jan. 13, 2021, 12:47 p.m.)
Deposited	4 years, 4 months ago (April 22, 2021, 3:01 p.m.)
Indexed	1 year, 7 months ago (Jan. 15, 2024, 5:42 a.m.)
Issued	34 years, 1 month ago (Aug. 1, 1991)
Published	34 years, 1 month ago (Aug. 1, 1991)
Published Online	34 years, 1 month ago (Aug. 1, 1991)
Published Print	34 years, 1 month ago (Aug. 1, 1991)

Funders 0

None

BibTeX

@article{Symington_1991, title={Genetic analysis of a meiotic recombination hotspot on chromosome III of Saccharomyces cerevisiae.}, volume={128}, ISSN={1943-2631}, url={http://dx.doi.org/10.1093/genetics/128.4.717}, DOI={10.1093/genetics/128.4.717}, number={4}, journal={Genetics}, publisher={Oxford University Press (OUP)}, author={Symington, L S and Brown, A and Oliver, S G and Greenwell, P and Petes, T D}, year={1991}, month=aug, pages={717–727} }

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