DOI: 10.1093/genetics/107.2.179. MUTATIONS AFFECTING TY-MEDIATED EXPRESSION OF THE <i>HIS4</i> GENE OF <i>SACCHAROMYCES CEREVISIAE</i>

MUTATIONS AFFECTING TY-MEDIATED EXPRESSION OF THE HIS4 GENE OF SACCHAROMYCES CEREVISIAE

10.1093/genetics/107.2.179

Crossref journal-article

Oxford University Press (OUP)

Genetics (286)

Abstract

ABSTRACT We have identified mutations in seven unlinked genes (SPT genes) that affect the phenotypes of Ty and δ insertion mutations in the 5′ noncoding region of the HIS4 gene of S. cerevisiae. Spt mutants were selected for suppression of his4-912δ, a solo δ derivative of Ty912. Other Ty and δ insertions at HIS4 are suppressed by mutations in some but not all of the SPT genes. Only spt4 suppresses a non-Ty insertion at HIS4. In addition to their effects on Ty and δ insertions, mutations in several SPT genes show defects in general cellular functions—mating. DNA repair and growth.

Bibliography

Winston, F., Chaleff, D. T., Valent, B., & Fink, G. R. (1984). MUTATIONS AFFECTING TY-MEDIATED EXPRESSION OF THE HIS4 GENE OF SACCHAROMYCES CEREVISIAE. Genetics, 107(2), 179â197.

Authors 4

Fred Winston (first)
Deborah T Chaleff (additional)
Barbara Valent (additional)
Gerald R Fink (additional)

References 0 Referenced 251

None

Dates

Type	When
Created	4 years, 7 months ago (Jan. 5, 2021, 8:47 p.m.)
Deposited	4 years, 4 months ago (April 22, 2021, 1:44 p.m.)
Indexed	2 weeks, 6 days ago (Aug. 3, 2025, 12:05 a.m.)
Issued	41 years, 2 months ago (June 1, 1984)
Published	41 years, 2 months ago (June 1, 1984)
Published Online	41 years, 2 months ago (June 1, 1984)
Published Print	41 years, 2 months ago (June 1, 1984)

Funders 0

None

BibTeX

@article{Winston_1984, title={MUTATIONS AFFECTING TY-MEDIATED EXPRESSION OF THE HIS4 GENE OF SACCHAROMYCES CEREVISIAE}, volume={107}, ISSN={1943-2631}, url={http://dx.doi.org/10.1093/genetics/107.2.179}, DOI={10.1093/genetics/107.2.179}, number={2}, journal={Genetics}, publisher={Oxford University Press (OUP)}, author={Winston, Fred and Chaleff, Deborah T and Valent, Barbara and Fink, Gerald R}, year={1984}, month=jun, pages={179–197} }

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