DOI: 10.1093/genetics/103.1.137. EVIDENCE FOR X-LINKAGE OF STEROID SULFATASE IN THE MOUSE: STEROID SULFATASE LEVELS IN OOCYTES OF <i>XX</i> AND <i>XO</i> MICE

EVIDENCE FOR X-LINKAGE OF STEROID SULFATASE IN THE MOUSE: STEROID SULFATASE LEVELS IN OOCYTES OF XX AND XO MICE

10.1093/genetics/103.1.137

Crossref journal-article

Oxford University Press (OUP)

Genetics (286)

Abstract

ABSTRACT The steroid sulfatase (STS) levels in mature oocytes of XX and XO mice were assayed along with lactate dehydrogenase (LDH), an autosomal marker, and glucose-6-phosphate dehydrogenase (G6PD), a known X-linked gene. LDH levels in XX and XO oocytes were equal, whereas STS and G6PD levels were approximately twice as high in XX oocytes as in XO oocytes. These results indicate that the STS gene is X-linked in the mouse just as it is in humans. Assays of STS in kidney tissue of XX and XO mice indicated dosage compensation for the gene, which is different from that observed in humans.

Bibliography

Gartler, S. M., & Rivest, M. (1983). EVIDENCE FOR X-LINKAGE OF STEROID SULFATASE IN THE MOUSE: STEROID SULFATASE LEVELS IN OOCYTES OF XX AND XO MICE. Genetics, 103(1), 137â141.

Authors 2

Stanley M Gartler (first)
Martha Rivest (additional)

References 0 Referenced 22

None

Dates

Type	When
Created	4 years, 7 months ago (Jan. 5, 2021, 5:28 p.m.)
Deposited	4 years, 4 months ago (April 22, 2021, 1:38 p.m.)
Indexed	4 months, 3 weeks ago (April 8, 2025, 10:21 p.m.)
Issued	42 years, 8 months ago (Jan. 1, 1983)
Published	42 years, 8 months ago (Jan. 1, 1983)
Published Online	42 years, 8 months ago (Jan. 1, 1983)
Published Print	42 years, 8 months ago (Jan. 1, 1983)

Funders 0

None

BibTeX

@article{Gartler_1983, title={EVIDENCE FOR X-LINKAGE OF STEROID SULFATASE IN THE MOUSE: STEROID SULFATASE LEVELS IN OOCYTES OF XX AND XO MICE}, volume={103}, ISSN={1943-2631}, url={http://dx.doi.org/10.1093/genetics/103.1.137}, DOI={10.1093/genetics/103.1.137}, number={1}, journal={Genetics}, publisher={Oxford University Press (OUP)}, author={Gartler, Stanley M and Rivest, Martha}, year={1983}, month=jan, pages={137–141} }

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