DOI: 10.1093/emboj/17.21.6219. Fc receptor-mediated phagocytosis requires CDC42 and Rac1

Fc receptor-mediated phagocytosis requires CDC42 and Rac1

10.1093/emboj/17.21.6219

Crossref journal-article

Springer Science and Business Media LLC

The EMBO Journal (297)

Bibliography

Massol, P., Montcourrier, P., Guillemot, J.-C., & Chavrier, P. (1998). Fc receptor-mediated phagocytosis requires CDC42 and Rac1. The EMBO Journal, 17(21), 6219â6229.

Authors 4

Philippe Massol (first)
Philippe Montcourrier (additional)
Jean-Claude Guillemot (additional)
Philippe Chavrier (additional)

References 47 Referenced 208

10.1083/jcb.111.1.131 / J Cell Biol / CDC42 and CDC43, two additional genes involved in budding and the establishment of cell polarity in the yeast Saccharomyces cerevisiae by Adams (1990)
10.1242/jcs.110.6.707 / J Cell Sci / Rho, Rac and Cdc42 regulate actin organization and cell adhesion in macrophages by Allen (1997)
10.1002/eji.1830270810 / Eur J Immunol / Src family-selective tyrosine kinase inhibitor, PP1, inhibits both FcϵRI- and Thy-1-mediated activation of rat basophilic leukemia cells by Amoui (1997)
10.1083/jcb.135.5.1249 / J Cell Biol / A role for phosphoinositide 3-kinase in the completion of macropinocytosis and phagocytosis by macrophages by Araki (1996)
10.1074/jbc.271.28.16597 / J Biol Chem / Syk tyrosine kinase is required for immunoreceptor tyrosine activation motif-dependent actin assembly by Cox (1996)
10.1084/jem.186.9.1487 / J Exp Med / Requirements for both Rac1 and Cdc42 in membrane ruffling and phagocytosis in leukocytes by Cox (1997)
10.1038/385169a0 / Nature / Phosphotyrosine-dependent activation of Rac1 GDP/GTP exchange by the vav proto-oncogene product by Crespo (1997)
10.1084/jem.186.7.1027 / J Exp Med / A critical role for Syk in signal transduction and phagocytosis mediated by Fcγ receptors on macrophages by Crowley (1997)
10.1093/intimm/5.11.1393 / Int Immunol / Distinct intracytoplasmic sequences are required for endocytosis and phagocytosis via murine FcγRII in mast cells by Daëron (1993)
10.4049/jimmunol.152.2.783 / J Immunol / Tyrosine-containing activation motif-dependent phagocytosis in mast cells by Daëron (1994)
10.4049/jimmunol.152.11.5429 / J Immunol / Stimulation of macrophage FcγRIIIA activates the receptor-associated protein tyrosine kinase Syk and induces phosphorylation of multiple proteins including p95vav and p62/GAP-associated protein by Darby (1994)
10.1016/S1074-7613(00)80273-3 / Immunity / Functional and physical interactions of Syk family kinases with the Vav proto-oncogene product by Deckert (1996)
10.1074/jbc.273.2.989 / J Biol Chem / Identification of a novel polyproline recognition site in the cytoskeletal associated protein, proline serine threonine phosphatase interacting protein by Dowbenko (1998)
10.1182/blood.V84.7.2102.2102 / Blood / Protein-tyrosine kinase p72syk in FcγRI receptor signaling by Durden (1994)
10.1016/S0021-9258(17)37050-3 / J Biol Chem / Physical and functional association of Src-related protein tyrosine kinases with FcγRII in monocytic THP-1 cells by Ghazizadeh (1994)
{'key': '10.1093/emboj/17.21.6219-BIB0016|embj7591314-citation-0016', 'first-page': '93', 'article-title': 'Signal transduction of phagocytosis', 'volume': '5', 'author': 'Greenberg', 'year': '1995', 'journal-title': 'Trends Biochem Sci'} / Trends Biochem Sci / Signal transduction of phagocytosis by Greenberg (1995)
10.1083/jcb.113.4.757 / J Cell Biol / Ca2+-independent F-actin assembly and disassembly during Fc receptor-mediated phagocytosis in mouse macrophages by Greenberg (1991)
10.1084/jem.177.2.529 / J Exp Med / Tyrosine phosphorylation is required for Fc receptor-mediated phagocytosis in mouse macrophages by Greenberg (1993)
10.1016/S0021-9258(17)41945-4 / J Biol Chem / Tyrosine phosphorylation of the γ subunit of Fcγ receptors, p72syk and paxillin during Fc receptor-mediated phagocytosis in macrophages by Greenberg (1994)
10.1073/pnas.93.3.1103 / Proc Natl Acad Sci USA / Clustered Syk tyrosine kinase domains trigger phagocytosis by Greenberg (1996)
10.1242/jcs.110.18.2215 / J Cell Sci / Selective control of membrane ruffling and actin plaque assembly by the Rho GTPases Rac1 and CDC42 in FcϵRI-activated rat basophilic leukemia (RBL-2H3) cells by Guillemot (1997)
10.1084/jem.186.6.955 / J Exp Med / Rho is required for the initiation of calcium signaling and phagocytosis by Fcγ receptors in macrophages by Hackam (1997)
10.1074/jbc.271.2.695 / J Biol Chem / Discovery of a novel, potent and Src family-selective tyrosine kinase inhibitor. Study of Lck- and FynT-dependent T cell activation by Hanke (1996)
10.1016/S0960-9822(95)00080-7 / Curr Biol / PDGF stimulates an increase in GTP-Rac via activation of phosphoinositide 3-kinase by Hawkins (1995)
10.4049/jimmunol.147.8.2670 / J Immunol / Monoclonal antibodies to the leukocyte common antigen (CD45) inhibit IgE-mediated histamine release from human basophils by Hook (1991)
10.1182/blood.V86.12.4389.bloodjournal86124389 / Blood / The molecular dissection of Fcγ receptor mediated phagocytosis by Indik (1995)
10.1016/1044-5323(95)90005-5 / Semin Immunol / Signal transduction through the conserved motifs of the high affinity IgE receptor FcϵRI by Jouvin (1995)
10.1038/375500a0 / Nature / Glucosylation of Rho proteins by Clostridium difficile toxin B by Just (1995)
10.1016/S0021-9258(20)80545-6 / J Biol Chem / Cross-linking of Fcγ receptor I (FcγRI) and receptor II (FcγRII) on monocytic cells activates a signal transduction pathway common to both Fc receptors that involves the stimulation of p72Syk protein tyrosine kinase by Kiener (1993)
10.1074/jbc.272.21.13991 / J Biol Chem / The negative signaling molecule SH2 domain-containing inositol-polyphosphate 5-phosphatase (SHIP) binds to the tyrosine-phosphorylated beta subunit of the high affinity IgE receptor by Kimura (1997)
10.1006/bbrc.1993.2424 / Biochem Biophys Res Commun / Characterization of a monoclonal antibody specific for the Ras-related GTP-binding protein Rho A by Lang (1993)
10.1038/356071a0 / Nature / Tyrosine phosphorylation of vav proto-oncogene product containing SH2 domain and transcription factor motifs by Margolis (1992)
10.1242/jcs.108.1.225 / J Cell Sci / Activation of the small GTP-binding proteins Rho and rac by growth factor receptors by Nobes (1995)
10.1083/jcb.101.6.2145 / J Cell Biol / Membrane and cytoskeletal changes associated with IgE-mediated serotonin release in rat basophilic leukemia cells by Pfeiffer (1985)
10.1006/excr.1996.0376 / Exp Cell Res / Focal adhesion and stress fiber formation is regulated by tyrosine phosphatase activity by Retta (1996)
10.1016/0092-8674(92)90164-8 / Cell / The small GTP-binding protein rac regulates growth factor-induced membrane ruffling by Ridley (1992)
10.1073/pnas.91.10.4140 / Proc Natl Acad Sci USA / Protein-tyrosine kinase activity tightly associated with human type II Fcγ receptors by Sarmay (1994)
10.1002/bies.950180109 / Bioessays / The pleckstrin homology domain: an intriguing multifunctional protein module by Shaw (1996)
10.1083/jcb.138.4.845 / J Cell Biol / PSTPIP: a tyrosine-phosphorylated cleavage furrow-associated protein that is a substrate for a PEST tyrosine phosphatase by Spencer (1997)
10.1016/S0962-8924(00)88956-4 / Trends Cell Biol / Phagocytosis by zippzers and triggers by Swanson (1995)
10.4049/jimmunol.155.11.5330 / J Immunol / Protein tyrosine phosphatase activity associates with the high affinity IgE receptor and dephosphorylates the receptor subunits, but not Lyn or Syk by Swieter (1995)
10.1016/S0955-0674(97)80156-1 / Curr Opin Cell Biol / Rho, Rac and Cdc42 GTPases regulate the organization of the actin cytoskeleton by Tapon (1997)
10.1084/jem.180.3.1165 / J Exp Med / Physical and functional association of the high affinity immunoglobulin G receptor (FcγRI) with the kinases Hck and Lyn by Wang (1994)
10.1016/S0960-9822(00)00087-7 / Curr Biol / Activation of phosphoinositide 3-kinase is required for PDGF-stimulated membrane ruffling by Wennström (1994)
10.1016/0092-8674(95)90369-0 / Cell / Hemostatic, inflammatory and fibroblast responses are blunted in mice lacking gelsolin by Witke (1995)
10.1074/jbc.273.10.5765 / J Biol Chem / Tyrosine phosphorylation regulates the SH3-mediated binding of the Wiskott-Aldrich syndrome protein to PSTPIP, a cytoskeletal-associated protein by Wu (1998)
10.1016/0014-4827(72)90062-6 / Exp Cell Res / Effects of cytochalasin B on polymorphonuclear leucocyte locomotion, phagocytosis and glycolysis by Zigmond (1972)

Dates

Type	When
Created	23 years, 1 month ago (July 26, 2002, 6:44 p.m.)
Deposited	1 year, 8 months ago (Dec. 18, 2023, 4:02 p.m.)
Indexed	1 month ago (July 28, 2025, 5:34 p.m.)
Issued	26 years, 9 months ago (Nov. 2, 1998)
Published	26 years, 9 months ago (Nov. 2, 1998)
Published Online	26 years, 9 months ago (Nov. 2, 1998)
Published Print	26 years, 9 months ago (Nov. 2, 1998)

Funders 0

None

BibTeX

@article{Massol_1998, title={Fc receptor-mediated phagocytosis requires CDC42 and Rac1}, volume={17}, ISSN={0261-4189}, url={http://dx.doi.org/10.1093/emboj/17.21.6219}, DOI={10.1093/emboj/17.21.6219}, number={21}, journal={The EMBO Journal}, publisher={Springer Science and Business Media LLC}, author={Massol, Philippe and Montcourrier, Philippe and Guillemot, Jean-Claude and Chavrier, Philippe}, year={1998}, month=nov, pages={6219–6229} }

JSON

{
  "indexed": {
    "date-parts": [
      [
        2025,
        7,
        28
      ]
    ],
    "date-time": "2025-07-28T21:34:50Z",
    "timestamp": 1753738490972
  },
  "reference-count": 47,
  "publisher": "Springer Science and Business Media LLC",
  "issue": "21",
  "license": [
    {
      "start": {
        "date-parts": [
          [
            2015,
            9,
            1
          ]
        ],
        "date-time": "2015-09-01T00:00:00Z",
        "timestamp": 1441065600000
      },
      "content-version": "tdm",
      "delay-in-days": 6147,
      "URL": "http://doi.wiley.com/10.1002/tdm_license_1.1"
    }
  ],
  "content-domain": {
    "domain": [],
    "crossmark-restriction": false
  },
  "published-print": {
    "date-parts": [
      [
        1998,
        11,
        2
      ]
    ]
  },
  "DOI": "10.1093/emboj/17.21.6219",
  "type": "journal-article",
  "created": {
    "date-parts": [
      [
        2002,
        7,
        26
      ]
    ],
    "date-time": "2002-07-26T22:44:48Z",
    "timestamp": 1027723488000
  },
  "page": "6219-6229",
  "source": "Crossref",
  "is-referenced-by-count": 208,
  "title": "Fc receptor-mediated phagocytosis requires CDC42 and Rac1",
  "prefix": "10.1038",
  "volume": "17",
  "author": [
    {
      "given": "Philippe",
      "family": "Massol",
      "sequence": "first",
      "affiliation": [
        {
          "name": "Centre d'Immunologie INSERM-CNRS de Marseille-Luminy, Case 906; 13288 Marseille Cedex 9 France"
        }
      ]
    },
    {
      "given": "Philippe",
      "family": "Montcourrier",
      "sequence": "additional",
      "affiliation": [
        {
          "name": "CNRS UMR 5539, Universit\u00e9 Montpellier II; 34095 Montpellier Cedex 5 France"
        }
      ]
    },
    {
      "given": "Jean-Claude",
      "family": "Guillemot",
      "sequence": "additional",
      "affiliation": [
        {
          "name": "Centre d'Immunologie INSERM-CNRS de Marseille-Luminy, Case 906; 13288 Marseille Cedex 9 France"
        }
      ]
    },
    {
      "given": "Philippe",
      "family": "Chavrier",
      "sequence": "additional",
      "affiliation": [
        {
          "name": "Centre d'Immunologie INSERM-CNRS de Marseille-Luminy, Case 906; 13288 Marseille Cedex 9 France"
        }
      ]
    }
  ],
  "member": "297",
  "published-online": {
    "date-parts": [
      [
        1998,
        11,
        2
      ]
    ]
  },
  "reference": [
    {
      "key": "10.1093/emboj/17.21.6219-BIB0001|embj7591314-citation-0001",
      "doi-asserted-by": "crossref",
      "first-page": "131",
      "DOI": "10.1083/jcb.111.1.131",
      "article-title": "CDC42 and CDC43, two additional genes involved in budding and the establishment of cell polarity in the yeast Saccharomyces cerevisiae",
      "volume": "111",
      "author": "Adams",
      "year": "1990",
      "journal-title": "J Cell Biol"
    },
    {
      "key": "10.1093/emboj/17.21.6219-BIB0002|embj7591314-citation-0002",
      "doi-asserted-by": "crossref",
      "first-page": "707",
      "DOI": "10.1242/jcs.110.6.707",
      "article-title": "Rho, Rac and Cdc42 regulate actin organization and cell adhesion in macrophages",
      "volume": "110",
      "author": "Allen",
      "year": "1997",
      "journal-title": "J Cell Sci"
    },
    {
      "key": "10.1093/emboj/17.21.6219-BIB0003|embj7591314-citation-0003",
      "doi-asserted-by": "crossref",
      "first-page": "1881",
      "DOI": "10.1002/eji.1830270810",
      "article-title": "Src family-selective tyrosine kinase inhibitor, PP1, inhibits both Fc\u03f5RI- and Thy-1-mediated activation of rat basophilic leukemia cells",
      "volume": "27",
      "author": "Amoui",
      "year": "1997",
      "journal-title": "Eur J Immunol"
    },
    {
      "key": "10.1093/emboj/17.21.6219-BIB0004|embj7591314-citation-0004",
      "doi-asserted-by": "crossref",
      "first-page": "1249",
      "DOI": "10.1083/jcb.135.5.1249",
      "article-title": "A role for phosphoinositide 3-kinase in the completion of macropinocytosis and phagocytosis by macrophages",
      "volume": "135",
      "author": "Araki",
      "year": "1996",
      "journal-title": "J Cell Biol"
    },
    {
      "key": "10.1093/emboj/17.21.6219-BIB0005|embj7591314-citation-0005",
      "doi-asserted-by": "crossref",
      "first-page": "16597",
      "DOI": "10.1074/jbc.271.28.16597",
      "article-title": "Syk tyrosine kinase is required for immunoreceptor tyrosine activation motif-dependent actin assembly",
      "volume": "271",
      "author": "Cox",
      "year": "1996",
      "journal-title": "J Biol Chem"
    },
    {
      "key": "10.1093/emboj/17.21.6219-BIB0006|embj7591314-citation-0006",
      "doi-asserted-by": "crossref",
      "first-page": "1487",
      "DOI": "10.1084/jem.186.9.1487",
      "article-title": "Requirements for both Rac1 and Cdc42 in membrane ruffling and phagocytosis in leukocytes",
      "volume": "186",
      "author": "Cox",
      "year": "1997",
      "journal-title": "J Exp Med"
    },
    {
      "key": "10.1093/emboj/17.21.6219-BIB0007|embj7591314-citation-0007",
      "doi-asserted-by": "crossref",
      "first-page": "169",
      "DOI": "10.1038/385169a0",
      "article-title": "Phosphotyrosine-dependent activation of Rac1 GDP/GTP exchange by the vav proto-oncogene product",
      "volume": "285",
      "author": "Crespo",
      "year": "1997",
      "journal-title": "Nature"
    },
    {
      "key": "10.1093/emboj/17.21.6219-BIB0008|embj7591314-citation-0008",
      "doi-asserted-by": "crossref",
      "first-page": "1027",
      "DOI": "10.1084/jem.186.7.1027",
      "article-title": "A critical role for Syk in signal transduction and phagocytosis mediated by Fc\u03b3 receptors on macrophages",
      "volume": "186",
      "author": "Crowley",
      "year": "1997",
      "journal-title": "J Exp Med"
    },
    {
      "key": "10.1093/emboj/17.21.6219-BIB0009|embj7591314-citation-0009",
      "doi-asserted-by": "crossref",
      "first-page": "1393",
      "DOI": "10.1093/intimm/5.11.1393",
      "article-title": "Distinct intracytoplasmic sequences are required for endocytosis and phagocytosis via murine Fc\u03b3RII in mast cells",
      "volume": "5",
      "author": "Da\u00ebron",
      "year": "1993",
      "journal-title": "Int Immunol"
    },
    {
      "key": "10.1093/emboj/17.21.6219-BIB0010|embj7591314-citation-0010",
      "doi-asserted-by": "crossref",
      "first-page": "783",
      "DOI": "10.4049/jimmunol.152.2.783",
      "article-title": "Tyrosine-containing activation motif-dependent phagocytosis in mast cells",
      "volume": "152",
      "author": "Da\u00ebron",
      "year": "1994",
      "journal-title": "J Immunol"
    },
    {
      "key": "10.1093/emboj/17.21.6219-BIB0011|embj7591314-citation-0011",
      "doi-asserted-by": "crossref",
      "first-page": "5429",
      "DOI": "10.4049/jimmunol.152.11.5429",
      "article-title": "Stimulation of macrophage Fc\u03b3RIIIA activates the receptor-associated protein tyrosine kinase Syk and induces phosphorylation of multiple proteins including p95vav and p62/GAP-associated protein",
      "volume": "152",
      "author": "Darby",
      "year": "1994",
      "journal-title": "J Immunol"
    },
    {
      "key": "10.1093/emboj/17.21.6219-BIB0012|embj7591314-citation-0012",
      "doi-asserted-by": "crossref",
      "first-page": "591",
      "DOI": "10.1016/S1074-7613(00)80273-3",
      "article-title": "Functional and physical interactions of Syk family kinases with the Vav proto-oncogene product",
      "volume": "5",
      "author": "Deckert",
      "year": "1996",
      "journal-title": "Immunity"
    },
    {
      "key": "10.1093/emboj/17.21.6219-BIB0013|embj7591314-citation-0013",
      "doi-asserted-by": "crossref",
      "first-page": "989",
      "DOI": "10.1074/jbc.273.2.989",
      "article-title": "Identification of a novel polyproline recognition site in the cytoskeletal associated protein, proline serine threonine phosphatase interacting protein",
      "volume": "273",
      "author": "Dowbenko",
      "year": "1998",
      "journal-title": "J Biol Chem"
    },
    {
      "key": "10.1093/emboj/17.21.6219-BIB0014|embj7591314-citation-0014",
      "doi-asserted-by": "crossref",
      "first-page": "2102",
      "DOI": "10.1182/blood.V84.7.2102.2102",
      "article-title": "Protein-tyrosine kinase p72syk in Fc\u03b3RI receptor signaling",
      "volume": "84",
      "author": "Durden",
      "year": "1994",
      "journal-title": "Blood"
    },
    {
      "key": "10.1093/emboj/17.21.6219-BIB0015|embj7591314-citation-0015",
      "doi-asserted-by": "crossref",
      "first-page": "8878",
      "DOI": "10.1016/S0021-9258(17)37050-3",
      "article-title": "Physical and functional association of Src-related protein tyrosine kinases with Fc\u03b3RII in monocytic THP-1 cells",
      "volume": "269",
      "author": "Ghazizadeh",
      "year": "1994",
      "journal-title": "J Biol Chem"
    },
    {
      "key": "10.1093/emboj/17.21.6219-BIB0016|embj7591314-citation-0016",
      "first-page": "93",
      "article-title": "Signal transduction of phagocytosis",
      "volume": "5",
      "author": "Greenberg",
      "year": "1995",
      "journal-title": "Trends Biochem Sci"
    },
    {
      "key": "10.1093/emboj/17.21.6219-BIB0017|embj7591314-citation-0017",
      "doi-asserted-by": "crossref",
      "first-page": "757",
      "DOI": "10.1083/jcb.113.4.757",
      "article-title": "Ca2+-independent F-actin assembly and disassembly during Fc receptor-mediated phagocytosis in mouse macrophages",
      "volume": "113",
      "author": "Greenberg",
      "year": "1991",
      "journal-title": "J Cell Biol"
    },
    {
      "key": "10.1093/emboj/17.21.6219-BIB0018|embj7591314-citation-0018",
      "doi-asserted-by": "crossref",
      "first-page": "529",
      "DOI": "10.1084/jem.177.2.529",
      "article-title": "Tyrosine phosphorylation is required for Fc receptor-mediated phagocytosis in mouse macrophages",
      "volume": "177",
      "author": "Greenberg",
      "year": "1993",
      "journal-title": "J Exp Med"
    },
    {
      "key": "10.1093/emboj/17.21.6219-BIB0019|embj7591314-citation-0019",
      "doi-asserted-by": "crossref",
      "first-page": "3897",
      "DOI": "10.1016/S0021-9258(17)41945-4",
      "article-title": "Tyrosine phosphorylation of the \u03b3 subunit of Fc\u03b3 receptors, p72syk and paxillin during Fc receptor-mediated phagocytosis in macrophages",
      "volume": "269",
      "author": "Greenberg",
      "year": "1994",
      "journal-title": "J Biol Chem"
    },
    {
      "key": "10.1093/emboj/17.21.6219-BIB0020|embj7591314-citation-0020",
      "doi-asserted-by": "crossref",
      "first-page": "1103",
      "DOI": "10.1073/pnas.93.3.1103",
      "article-title": "Clustered Syk tyrosine kinase domains trigger phagocytosis",
      "volume": "93",
      "author": "Greenberg",
      "year": "1996",
      "journal-title": "Proc Natl Acad Sci USA"
    },
    {
      "key": "10.1093/emboj/17.21.6219-BIB0021|embj7591314-citation-0021",
      "doi-asserted-by": "crossref",
      "first-page": "2215",
      "DOI": "10.1242/jcs.110.18.2215",
      "article-title": "Selective control of membrane ruffling and actin plaque assembly by the Rho GTPases Rac1 and CDC42 in Fc\u03f5RI-activated rat basophilic leukemia (RBL-2H3) cells",
      "volume": "110",
      "author": "Guillemot",
      "year": "1997",
      "journal-title": "J Cell Sci"
    },
    {
      "key": "10.1093/emboj/17.21.6219-BIB0022|embj7591314-citation-0022",
      "doi-asserted-by": "crossref",
      "first-page": "955",
      "DOI": "10.1084/jem.186.6.955",
      "article-title": "Rho is required for the initiation of calcium signaling and phagocytosis by Fc\u03b3 receptors in macrophages",
      "volume": "186",
      "author": "Hackam",
      "year": "1997",
      "journal-title": "J Exp Med"
    },
    {
      "key": "10.1093/emboj/17.21.6219-BIB0023|embj7591314-citation-0023",
      "doi-asserted-by": "crossref",
      "first-page": "695",
      "DOI": "10.1074/jbc.271.2.695",
      "article-title": "Discovery of a novel, potent and Src family-selective tyrosine kinase inhibitor. Study of Lck- and FynT-dependent T cell activation",
      "volume": "271",
      "author": "Hanke",
      "year": "1996",
      "journal-title": "J Biol Chem"
    },
    {
      "key": "10.1093/emboj/17.21.6219-BIB0024|embj7591314-citation-0024",
      "doi-asserted-by": "crossref",
      "first-page": "393",
      "DOI": "10.1016/S0960-9822(95)00080-7",
      "article-title": "PDGF stimulates an increase in GTP-Rac via activation of phosphoinositide 3-kinase",
      "volume": "5",
      "author": "Hawkins",
      "year": "1995",
      "journal-title": "Curr Biol"
    },
    {
      "key": "10.1093/emboj/17.21.6219-BIB0025|embj7591314-citation-0025",
      "doi-asserted-by": "crossref",
      "first-page": "2670",
      "DOI": "10.4049/jimmunol.147.8.2670",
      "article-title": "Monoclonal antibodies to the leukocyte common antigen (CD45) inhibit IgE-mediated histamine release from human basophils",
      "volume": "147",
      "author": "Hook",
      "year": "1991",
      "journal-title": "J Immunol"
    },
    {
      "key": "10.1093/emboj/17.21.6219-BIB0026|embj7591314-citation-0026",
      "doi-asserted-by": "crossref",
      "first-page": "4389",
      "DOI": "10.1182/blood.V86.12.4389.bloodjournal86124389",
      "article-title": "The molecular dissection of Fc\u03b3 receptor mediated phagocytosis",
      "volume": "86",
      "author": "Indik",
      "year": "1995",
      "journal-title": "Blood"
    },
    {
      "key": "10.1093/emboj/17.21.6219-BIB0027|embj7591314-citation-0027",
      "doi-asserted-by": "crossref",
      "first-page": "29",
      "DOI": "10.1016/1044-5323(95)90005-5",
      "article-title": "Signal transduction through the conserved motifs of the high affinity IgE receptor Fc\u03f5RI",
      "volume": "7",
      "author": "Jouvin",
      "year": "1995",
      "journal-title": "Semin Immunol"
    },
    {
      "key": "10.1093/emboj/17.21.6219-BIB0028|embj7591314-citation-0028",
      "doi-asserted-by": "crossref",
      "first-page": "500",
      "DOI": "10.1038/375500a0",
      "article-title": "Glucosylation of Rho proteins by Clostridium difficile toxin B",
      "volume": "375",
      "author": "Just",
      "year": "1995",
      "journal-title": "Nature"
    },
    {
      "key": "10.1093/emboj/17.21.6219-BIB0029|embj7591314-citation-0029",
      "doi-asserted-by": "crossref",
      "first-page": "24442",
      "DOI": "10.1016/S0021-9258(20)80545-6",
      "article-title": "Cross-linking of Fc\u03b3 receptor I (Fc\u03b3RI) and receptor II (Fc\u03b3RII) on monocytic cells activates a signal transduction pathway common to both Fc receptors that involves the stimulation of p72Syk protein tyrosine kinase",
      "volume": "268",
      "author": "Kiener",
      "year": "1993",
      "journal-title": "J Biol Chem"
    },
    {
      "key": "10.1093/emboj/17.21.6219-BIB0030|embj7591314-citation-0030",
      "doi-asserted-by": "crossref",
      "first-page": "13991",
      "DOI": "10.1074/jbc.272.21.13991",
      "article-title": "The negative signaling molecule SH2 domain-containing inositol-polyphosphate 5-phosphatase (SHIP) binds to the tyrosine-phosphorylated beta subunit of the high affinity IgE receptor",
      "volume": "272",
      "author": "Kimura",
      "year": "1997",
      "journal-title": "J Biol Chem"
    },
    {
      "key": "10.1093/emboj/17.21.6219-BIB0031|embj7591314-citation-0031",
      "doi-asserted-by": "crossref",
      "first-page": "1522",
      "DOI": "10.1006/bbrc.1993.2424",
      "article-title": "Characterization of a monoclonal antibody specific for the Ras-related GTP-binding protein Rho A",
      "volume": "196",
      "author": "Lang",
      "year": "1993",
      "journal-title": "Biochem Biophys Res Commun"
    },
    {
      "key": "10.1093/emboj/17.21.6219-BIB0032|embj7591314-citation-0032",
      "doi-asserted-by": "crossref",
      "first-page": "71",
      "DOI": "10.1038/356071a0",
      "article-title": "Tyrosine phosphorylation of vav proto-oncogene product containing SH2 domain and transcription factor motifs",
      "volume": "356",
      "author": "Margolis",
      "year": "1992",
      "journal-title": "Nature"
    },
    {
      "key": "10.1093/emboj/17.21.6219-BIB0033|embj7591314-citation-0033",
      "doi-asserted-by": "crossref",
      "first-page": "225",
      "DOI": "10.1242/jcs.108.1.225",
      "article-title": "Activation of the small GTP-binding proteins Rho and rac by growth factor receptors",
      "volume": "108",
      "author": "Nobes",
      "year": "1995",
      "journal-title": "J Cell Sci"
    },
    {
      "key": "10.1093/emboj/17.21.6219-BIB0034|embj7591314-citation-0034",
      "doi-asserted-by": "crossref",
      "first-page": "2145",
      "DOI": "10.1083/jcb.101.6.2145",
      "article-title": "Membrane and cytoskeletal changes associated with IgE-mediated serotonin release in rat basophilic leukemia cells",
      "volume": "101",
      "author": "Pfeiffer",
      "year": "1985",
      "journal-title": "J Cell Biol"
    },
    {
      "key": "10.1093/emboj/17.21.6219-BIB0035|embj7591314-citation-0035",
      "doi-asserted-by": "crossref",
      "first-page": "307",
      "DOI": "10.1006/excr.1996.0376",
      "article-title": "Focal adhesion and stress fiber formation is regulated by tyrosine phosphatase activity",
      "volume": "229",
      "author": "Retta",
      "year": "1996",
      "journal-title": "Exp Cell Res"
    },
    {
      "key": "10.1093/emboj/17.21.6219-BIB0036|embj7591314-citation-0036",
      "doi-asserted-by": "crossref",
      "first-page": "401",
      "DOI": "10.1016/0092-8674(92)90164-8",
      "article-title": "The small GTP-binding protein rac regulates growth factor-induced membrane ruffling",
      "volume": "70",
      "author": "Ridley",
      "year": "1992",
      "journal-title": "Cell"
    },
    {
      "key": "10.1093/emboj/17.21.6219-BIB0037|embj7591314-citation-0037",
      "doi-asserted-by": "crossref",
      "first-page": "4140",
      "DOI": "10.1073/pnas.91.10.4140",
      "article-title": "Protein-tyrosine kinase activity tightly associated with human type II Fc\u03b3 receptors",
      "volume": "91",
      "author": "Sarmay",
      "year": "1994",
      "journal-title": "Proc Natl Acad Sci USA"
    },
    {
      "key": "10.1093/emboj/17.21.6219-BIB0038|embj7591314-citation-0038",
      "doi-asserted-by": "crossref",
      "first-page": "35",
      "DOI": "10.1002/bies.950180109",
      "article-title": "The pleckstrin homology domain: an intriguing multifunctional protein module",
      "volume": "18",
      "author": "Shaw",
      "year": "1996",
      "journal-title": "Bioessays"
    },
    {
      "key": "10.1093/emboj/17.21.6219-BIB0039|embj7591314-citation-0039",
      "doi-asserted-by": "crossref",
      "first-page": "845",
      "DOI": "10.1083/jcb.138.4.845",
      "article-title": "PSTPIP: a tyrosine-phosphorylated cleavage furrow-associated protein that is a substrate for a PEST tyrosine phosphatase",
      "volume": "138",
      "author": "Spencer",
      "year": "1997",
      "journal-title": "J Cell Biol"
    },
    {
      "key": "10.1093/emboj/17.21.6219-BIB0040|embj7591314-citation-0040",
      "doi-asserted-by": "crossref",
      "first-page": "89",
      "DOI": "10.1016/S0962-8924(00)88956-4",
      "article-title": "Phagocytosis by zippzers and triggers",
      "volume": "5",
      "author": "Swanson",
      "year": "1995",
      "journal-title": "Trends Cell Biol"
    },
    {
      "key": "10.1093/emboj/17.21.6219-BIB0041|embj7591314-citation-0041",
      "doi-asserted-by": "crossref",
      "first-page": "5330",
      "DOI": "10.4049/jimmunol.155.11.5330",
      "article-title": "Protein tyrosine phosphatase activity associates with the high affinity IgE receptor and dephosphorylates the receptor subunits, but not Lyn or Syk",
      "volume": "155",
      "author": "Swieter",
      "year": "1995",
      "journal-title": "J Immunol"
    },
    {
      "key": "10.1093/emboj/17.21.6219-BIB0042|embj7591314-citation-0042",
      "doi-asserted-by": "crossref",
      "first-page": "86",
      "DOI": "10.1016/S0955-0674(97)80156-1",
      "article-title": "Rho, Rac and Cdc42 GTPases regulate the organization of the actin cytoskeleton",
      "volume": "9",
      "author": "Tapon",
      "year": "1997",
      "journal-title": "Curr Opin Cell Biol"
    },
    {
      "key": "10.1093/emboj/17.21.6219-BIB0043|embj7591314-citation-0043",
      "doi-asserted-by": "crossref",
      "first-page": "1165",
      "DOI": "10.1084/jem.180.3.1165",
      "article-title": "Physical and functional association of the high affinity immunoglobulin G receptor (Fc\u03b3RI) with the kinases Hck and Lyn",
      "volume": "180",
      "author": "Wang",
      "year": "1994",
      "journal-title": "J Exp Med"
    },
    {
      "key": "10.1093/emboj/17.21.6219-BIB0044|embj7591314-citation-0044",
      "doi-asserted-by": "crossref",
      "first-page": "385",
      "DOI": "10.1016/S0960-9822(00)00087-7",
      "article-title": "Activation of phosphoinositide 3-kinase is required for PDGF-stimulated membrane ruffling",
      "volume": "4",
      "author": "Wennstr\u00f6m",
      "year": "1994",
      "journal-title": "Curr Biol"
    },
    {
      "key": "10.1093/emboj/17.21.6219-BIB0045|embj7591314-citation-0045",
      "doi-asserted-by": "crossref",
      "first-page": "41",
      "DOI": "10.1016/0092-8674(95)90369-0",
      "article-title": "Hemostatic, inflammatory and fibroblast responses are blunted in mice lacking gelsolin",
      "volume": "81",
      "author": "Witke",
      "year": "1995",
      "journal-title": "Cell"
    },
    {
      "key": "10.1093/emboj/17.21.6219-BIB0046|embj7591314-citation-0046",
      "doi-asserted-by": "crossref",
      "first-page": "5765",
      "DOI": "10.1074/jbc.273.10.5765",
      "article-title": "Tyrosine phosphorylation regulates the SH3-mediated binding of the Wiskott-Aldrich syndrome protein to PSTPIP, a cytoskeletal-associated protein",
      "volume": "273",
      "author": "Wu",
      "year": "1998",
      "journal-title": "J Biol Chem"
    },
    {
      "key": "10.1093/emboj/17.21.6219-BIB0047|embj7591314-citation-0047",
      "doi-asserted-by": "crossref",
      "first-page": "383",
      "DOI": "10.1016/0014-4827(72)90062-6",
      "article-title": "Effects of cytochalasin B on polymorphonuclear leucocyte locomotion, phagocytosis and glycolysis",
      "volume": "73",
      "author": "Zigmond",
      "year": "1972",
      "journal-title": "Exp Cell Res"
    }
  ],
  "container-title": "The EMBO Journal",
  "original-title": [],
  "language": "en",
  "link": [
    {
      "URL": "https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1093%2Femboj%2F17.21.6219",
      "content-type": "unspecified",
      "content-version": "vor",
      "intended-application": "text-mining"
    },
    {
      "URL": "https://onlinelibrary.wiley.com/doi/full/10.1093/emboj/17.21.6219",
      "content-type": "unspecified",
      "content-version": "vor",
      "intended-application": "similarity-checking"
    }
  ],
  "deposited": {
    "date-parts": [
      [
        2023,
        12,
        18
      ]
    ],
    "date-time": "2023-12-18T21:02:39Z",
    "timestamp": 1702933359000
  },
  "score": 1,
  "resource": {
    "primary": {
      "URL": "http://emboj.embopress.org/cgi/doi/10.1093/emboj/17.21.6219"
    }
  },
  "subtitle": [],
  "short-title": [],
  "issued": {
    "date-parts": [
      [
        1998,
        11,
        2
      ]
    ]
  },
  "references-count": 47,
  "journal-issue": {
    "issue": "21",
    "published-print": {
      "date-parts": [
        [
          1998,
          11,
          2
        ]
      ]
    }
  },
  "URL": "http://dx.doi.org/10.1093/emboj/17.21.6219",
  "relation": {},
  "ISSN": [
    "0261-4189"
  ],
  "subject": [],
  "published": {
    "date-parts": [
      [
        1998,
        11,
        2
      ]
    ]
  }
}