DOI: 10.1093/clinchem/36.2.251. SCC antigen measured in malignant and nonmalignant diseases

SCC antigen measured in malignant and nonmalignant diseases

10.1093/clinchem/36.2.251

Crossref journal-article

Oxford University Press (OUP)

Clinical Chemistry (286)

Abstract

Abstract SCC antigen was measured in the serum of 214 patients with benign diseases and in 251 patients with various cancers. With 2.5 micrograms/L as the upper normal limit for serum, values were positive in 2.9% of 69 healthy subjects (I), 29.0% of 214 patients with benign pathologies (II), and 41% of 217 patients with active cancer (III). The highest values in group II were for patients in renal failure (64%) or with lung diseases (40%) or head-and-neck diseases (21.2%). Specificity of SCC increased (91.1%) when we excluded patients in renal failure or with creatinine values greater than 133 mumol/L. In group III, SCC values were abnormal in 57.7% of patients with squamous cell carcinoma, but in only 9.3% of those with other histological types (P less than 0.001). In squamous cell carcinoma of the lung, cervix, or head and neck, SCC values were related to tumor stage, values being highest in patients with metastases.

Bibliography

Molina, R., Filella, X., Torres, M. D., Ballesta, A. M., Mengual, P., Cases, A., & Balaque, A. (1990). SCC antigen measured in malignant and nonmalignant diseases. Clinical Chemistry, 36(2), 251â254.

Authors 7

R Molina (first)
X Filella (first)
M D Torres (first)
A M Ballesta (first)
P Mengual (first)
A Cases (first)
A Balaque (first)

References 0 Referenced 46

None

Dates

Type	When
Created	5 years, 7 months ago (Jan. 10, 2020, 11:38 p.m.)
Deposited	5 years, 6 months ago (March 2, 2020, 8:01 p.m.)
Indexed	2 months, 2 weeks ago (June 21, 2025, 12:49 a.m.)
Issued	35 years, 7 months ago (Feb. 1, 1990)
Published	35 years, 7 months ago (Feb. 1, 1990)
Published Online	35 years, 7 months ago (Feb. 1, 1990)
Published Print	35 years, 7 months ago (Feb. 1, 1990)

Funders 0

None

BibTeX

@article{Molina_1990, title={SCC antigen measured in malignant and nonmalignant diseases}, volume={36}, ISSN={1530-8561}, url={http://dx.doi.org/10.1093/clinchem/36.2.251}, DOI={10.1093/clinchem/36.2.251}, number={2}, journal={Clinical Chemistry}, publisher={Oxford University Press (OUP)}, author={Molina, R and Filella, X and Torres, M D and Ballesta, A M and Mengual, P and Cases, A and Balaque, A}, year={1990}, month=feb, pages={251–254} }

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