DOI: 10.1093/clinchem/21.2.190. Comparison of Methods for Calculating Serum Osmolality from Chemical Concentrations, and the Prognostic Value of Such Calculations [Penn]

Comparison of Methods for Calculating Serum Osmolality from Chemical Concentrations, and the Prognostic Value of Such Calculations

10.1093/clinchem/21.2.190

Crossref journal-article

Oxford University Press (OUP)

Clinical Chemistry (286)

Abstract

Abstract Sodium, potassium, glucose, blood urea nitrogen, and osmolality were determined for 715 hospital-patient sera. The chemical concentrations were used to calculate osmolalities according to 13 different methods taken from the literature. The goodness of the comparison between calculated and measured osmolality was quite similar for several of the better methods. The agreement was unimproved when molal chemical concentrations were used instead of molar values. The difference between measured and calculated osmolality was unrelated to whether a patient was discharged from the hospital after a short or long period or ultimately died. The equation we found to yield the most accurately calculated osmolalities is

Bibliography

Dorwart, W. V., & Chalmers, L. (1975). Comparison of Methods for Calculating Serum Osmolality from Chemical Concentrations, and the Prognostic Value of Such Calculations. Clinical Chemistry, 21(2), 190â194.

Authors 2

William V Dorwart (first)
Leslie Chalmers (first)

References 0 Referenced 147

None

Dates

Type	When
Created	5 years, 7 months ago (Jan. 20, 2020, 3:19 a.m.)
Deposited	5 years, 5 months ago (March 5, 2020, 11:35 p.m.)
Indexed	1 week ago (Aug. 22, 2025, 1:01 a.m.)
Issued	50 years, 6 months ago (Feb. 1, 1975)
Published	50 years, 6 months ago (Feb. 1, 1975)
Published Online	50 years, 6 months ago (Feb. 1, 1975)
Published Print	50 years, 6 months ago (Feb. 1, 1975)

Funders 0

None

BibTeX

@article{Dorwart_1975, title={Comparison of Methods for Calculating Serum Osmolality from Chemical Concentrations, and the Prognostic Value of Such Calculations}, volume={21}, ISSN={1530-8561}, url={http://dx.doi.org/10.1093/clinchem/21.2.190}, DOI={10.1093/clinchem/21.2.190}, number={2}, journal={Clinical Chemistry}, publisher={Oxford University Press (OUP)}, author={Dorwart, William V and Chalmers, Leslie}, year={1975}, month=feb, pages={190–194} }

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