DOI: 10.1093/carcin/20.3.415. Overexpression of the human HAP1 protein sensitizes cells to the lethal effect of bioreductive drugs

Overexpression of the human HAP1 protein sensitizes cells to the lethal effect of bioreductive drugs

10.1093/carcin/20.3.415

Crossref journal-article

Oxford University Press (OUP)

Carcinogenesis (286)

Bibliography

Prieto-Alamo, M. J., & Laval, F. (1999). Overexpression of the human HAP1 protein sensitizes cells to the lethal effect of bioreductive drugs. Carcinogenesis, 20(3), 415â419.

Authors 2

Maria José Prieto-Alamo (first)
Francıoise Laval (additional)

References 32 Referenced 26

Barzilay,G. and Hickson,I.D. (1995) Structure and function of apurinic/apyrimidinic endonucleases. Bioessays, 17, 713–719. (10.1002/bies.950170808)
Lindahl,T. (1990) Repair of intrinsic DNA lesions. Mutat. Res., 238, 305–311. (10.1016/0165-1110(90)90022-4)
Boiteux,S. and Laval,J. (1982) Coding properties of poly(deoxycytidylic acid) templates containing uracil or apyrimidinic sites: in vitro modulation of mutagenesis by deoxyribonucleic acid repair enzymes. Biochemistry, 21, 6746–6749. (10.1021/bi00269a020)
Robson,C.N. and Hickson,I.D. (1991) Isolation of cDNA clones encoding a human apurinic/apyrimidinic endonuclease that corrects DNA repair and mutagenesis defects of E.coli xth (endonuclease III) mutants. Nucleic Acids Res., 9, 5519–5523. (10.1093/nar/19.20.5519)
Demple,B., Herman,T. and Chen,D.S. (1991) Cloning and expression of APE, the cDNA encoding the major human apurinic endonuclease: definition of a family of DNA repair enzymes. Proc. Natl Acad. Sci. USA, 88, 11450–11454. (10.1073/pnas.88.24.11450)
Xanthoudakis,S. and Curran,T. (1992) Identification and characterization of Ref-1, a nuclear protein that facilitates AP-1 DNA-binding activity. EMBO J., 11, 653–665.
Rainwater,R., Parks,D., Anderson,M.E., Tegtmeyer,P. and Mann,K. (1995) Role of cysteine residues in regulation of p53 function. Mol. Cell. Biol., 15, 3892–3903. (10.1128/MCB.15.7.3892)
Rothwell,D.J. and Hickson,I.D. (1996) Asparagine 212 is essential for abasic site recognition by the human DNA repair endonuclease HAP1. Nucleic Acids Res., 24, 4217–4221. (10.1093/nar/24.21.4217)
Walker,L.J., Robson,C.N., Black,E., Gillepsie,D. and Hickson,I.D. (1993) Identification of residues in the human repair enzyme HAP1 (Ref-1) that are essential for redox regulation of Jun DNA binding. Mol. Cell. Biol., 13, 5370–5376. (10.1128/MCB.13.9.5370)
Gorman,M.A., Morera,S., Rothwell,D.G., de la Fortelle,E., Mol,C.D., Tainer,J.A., Hickson,I.D. and Freemont,P.S. (1997) The crystal structure of the human DNA repair endonuclease HAP1 suggests the recognition of extra-helical deoxyribose at DNA abasic sites. EMBO J., 16, 6548–6558. (10.1093/emboj/16.21.6548)
Chen,D.S., Law,C. and Keng,P. (1993) Reduction of radiation cytotoxicity by human apurinic endonuclease in radiation sensitive E. coli mutant. Radiat. Res., 135, 405–410. (10.2307/3578882)
Laval,F. (1994) Expression of the fpg gene in mammalian cells reduces the mutagenicity of γ-rays. Nucleic Acids Res., 23, 4943–4946. (10.1093/nar/22.23.4943)
Habraken,Y. and Laval,F. (1993) Increased resistance of the Chinese hamster mutant irs1 cells to monofunctional alkylating agents by transfection of the E. coli or mammalian N3-methyladenine-DNA glycosylases. Mutat. Res., 293, 187–195. (10.1016/0921-8777(93)90069-S)
Cool,B.L. and Sirover,M.A. (1898) Immunocytochemical localization of the base excision repair enzyme uracil DNA glycosylase in quiescent and proliferating normal human cells. Cancer Res., 49, 3029–3036.
Yuckenberg,P.D., Witney,F., Geisselsoder,J. and McClary,J. (1991) Site-directed in vitro mutagenesis using uracil-containing DNA and phagemid vectors. In McPherson,M.J. (ed.) Directed Mutagenesis, A Practical Approach. Oxford University Press, Oxford, UK.Yuckenberg,P.D., Witney,F., Geisselsoder,J. and McClary,J. (1991) Site-directed in vitro mutagenesis using uracil-containing DNA and phagemid vectors. In McPherson,M.J. (ed.) Directed Mutagenesis, A Practical Approach. Oxford University Press, Oxford, UK. (10.1093/oso/9780199631414.003.0002)
Deutsch Murphy,L., Herzog,C.E., Rudick,J.B., Tito,A. and Bates,S.E. (1990) Use of polymerase chain reaction in the quantitation of mdr-1 gene expression. Biochemistry, 29, 10351–10356. (10.1021/bi00497a009)
Paquette,Y., Crine,P. and Verly,W.G. (1972) Properties of the endonuclease for depurinated DNA from E. coli. Can. J. Biochem., 50, 1199–1209. (10.1139/o72-163)
Devary,Y., Gottlieb,R.A., Smeal,T. and Karin,M. (1992) The mammalian ultraviolet response is triggered by activation of Scr tyrosine kinases. Cell, 71, 1081–1091. (10.1016/S0092-8674(05)80058-3)
Winters,T.A., Henner,W.D., Russell,P.S., McCullough,A. and Jorgensen,T.J. (1994) Removal of 3′-phosphoglycolate from DNA strand-break damage in an oligonucleotide substrate by recombinant human apurinic/apyrimidinic endonuclease 1. Nucleic Acids Res., 22, 1866–1873. (10.1093/nar/22.10.1866)
Wilson,D.M., Bennett,R.A.O., Marquis,J.C., Ansari,P. and Demple,B. (1995) Trans-complementation by human apurinic endonuclease (Ape) of hypersensitivity to DNA damage and spontaneous mutator phenotype in apn1– yeast. Nucleic Acids Res., 23, 5027–5033. (10.1093/nar/23.24.5027)
Ono,Y., Futura,T., Ohmoto,T., Akiyama,K. and Seki,S. (1994) Stable expression in rat glioma cells of sense and antisense nucleic acids to a human multifunctional DNA repair enzyme, APEX nuclease. Mutat. Res., 315, 55–63. (10.1016/0921-8777(94)90028-0)
Xanthoudakis,S., Smeyne,R.J., Wallace,J.D. and Curran,T. (1996) The redox/DNA repair protein, Ref-1, is essential for early embryonic development in mice. Proc. Natl Acad. Sci. USA, 93, 8919–8923. (10.1073/pnas.93.17.8919)
Walker,L.J., Craig,R.B., Harris,A.L. and Hickson,I.D. (1994) A role for the human DNA repair enzyme HAP1 in cellular protection against DNA damaging agents and hypoxic stress. Nucleic Acids Res., 22, 4884–4889. (10.1093/nar/22.23.4884)
Basu,A.K., Hanrahan,C.J., Malia,S.A., Kumar,S., Bizanek,R. and Tomasz,M. (1993) Effect of site-specifically located mitomycin C–DNA monoadducts on in vitro DNA synthesis by DNA polymerases. Biochemistry, 32, 4708–4718. (10.1021/bi00069a004)
Krishna,M.C., DeGraff,W., Tamura,S. Gonzalez,F.J., Samuni,A., Russo,A. and Mitchell,J.B. (1991) Mechanisms of hypoxic and aerobic cytotoxicity of mitomycin C in Chinese hamster V79 cells. Cancer Res., 51, 6622–6628.
Warren,A.J., Maccubbin,A.E. and Hamilton,J.W. (1998) Detection of mitomycin C–DNA adducts in vivo by 32P-postlabelling: time course for formation and removal of adducts and biochemical modulation. Cancer Res., 58, 453–464.
Traver,R.D., Horikoshi,T., Danenberg,K.D., Stadlbauer,T.H.W. and Danenberg,P.V. (1992) NAD(P)H:quinone oxidoreductase gene expression in human colon carcinoma cells: characterization of a mutation which modulates DT-diaphorase activity and mitomycin sensitivity. Cancer Res., 52, 797–802.
Hodnick,W.E. and Sartorelli,A.C. (1993) Reductive activation of mitomycin C by NADH:cytochrome b5 reductase. Cancer Res., 53, 4907–4912.
Sharma,M., Qy,H., and Tomasz,M. (1994) Effects of gluthatione on alkylation and cross-linking of DNA by mitomycin C. Isolation of a ternary glutathione–mitomycin–DNA adduct. Chem. Res. Toxicol., 7, 401–407. (10.1021/tx00039a018)
Yu,F. and Pan,S.S. (1993) Effect of pH on DNA alkykation by enzyme-activated mitomycin C and porfiromycin. Mol. Pharmacol., 43, 863–869.
Bercourt,M.F., Hodnick,W.F., Rockwell,S. and Sartorelli,A.C. (1996) Differential toxicitiy of mitomycin C and porfiromycin to aerobic and hypoxic Chinese hamster ovary cells overexpressing human NADPH:cytochrome c (P-450) reductase. Proc. Natl Acad. Sci. USA, 93, 456–460. (10.1073/pnas.93.1.456)
Gibson,N.W., Hartley,J.A., Butler,J., Siegler,D. and Ross,D. (1992) Relationship between DT-diaphorase-mediated metabolism of a series of aziridinebenzoquinones and DNA damage and cytotoxicity. Mol. Pharmacol., 42, 531–536.

Dates

Type	When
Created	23 years, 1 month ago (July 26, 2002, 6:20 p.m.)
Deposited	1 year, 8 months ago (Jan. 4, 2024, 6:36 p.m.)
Indexed	1 year, 2 months ago (June 9, 2024, 10:12 a.m.)
Issued	26 years, 6 months ago (March 1, 1999)
Published	26 years, 6 months ago (March 1, 1999)
Published Online	26 years, 6 months ago (March 1, 1999)
Published Print	26 years, 6 months ago (March 1, 1999)

Funders 0

None

BibTeX

@article{Prieto_Alamo_1999, title={Overexpression of the human HAP1 protein sensitizes cells to the lethal effect of bioreductive drugs}, volume={20}, ISSN={0143-3334}, url={http://dx.doi.org/10.1093/carcin/20.3.415}, DOI={10.1093/carcin/20.3.415}, number={3}, journal={Carcinogenesis}, publisher={Oxford University Press (OUP)}, author={Prieto-Alamo, Maria José and Laval, Francıoise}, year={1999}, month=mar, pages={415–419} }

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