DOI: 10.1093/bmb/66.1.161. Subclinical prion infection in humans and animals

Subclinical prion infection in humans and animals

10.1093/bmb/66.1.161

Crossref journal-article

Oxford University Press (OUP)

British Medical Bulletin (286)

Bibliography

Hill, A. F., & Collinge, J. (2003). Subclinical prion infection in humans and animals. British Medical Bulletin, 66(1), 161â170.

Authors 2

Andrew F Hill (first)
John Collinge (additional)

References 38 Referenced 63

Prusiner SB. Novel proteinaceous infectious particles cause scrapie. Science1982; 216: 136–44 (10.1126/science.6801762)
Büeler H, Aguzzi A, Sailer A et al. Mice devoid of PrP are resistant to scrapie. Cell1993; 73: 1339–47 (10.1016/0092-8674(93)90360-3)
Bruce ME, Fraser H, McBride PA, Scott JR, Dickinson AG. The basis of strain variation in scrapie. In: Prusiner SB, Collinge J, Powell J, Anderton B. (eds) Prion Diseases in Human and Animals. London: Ellis Horwood, 1992: 497–508
Bruce M, Chree A, McConnell I, Foster J, Pearson G, Fraser H. Transmission of bovine spongiform encephalopathy and scrapie to mice: strain variation and the species barrier. Philos Trans R Soc Lond B Biol Sci1994; 343: 405–11 (10.1098/rstb.1994.0036)
Bessen RA, Marsh RF. Biochemical and physical properties of the prion protein from two strains of the transmissible mink encephalopathy agent. J Virol1992; 66: 2096–101 (10.1128/JVI.66.4.2096-2101.1992)
Bessen RA, Marsh RF. Distinct PrP properties suggest the molecular basis of strain variation in transmissible mink encephalopathy. J Virol1994; 68: 7859–68 (10.1128/JVI.68.12.7859-7868.1994)
Collinge J, Sidle KCL, Meads J, Ironside J, Hill AF. Molecular analysis of prion strain variation and the aetiology of ‘new variant’ CJD. Nature1996; 383: 685–90 (10.1038/383685a0)
Parchi P, Giese A, Capellari S et al. Classification of sporadic Creutzfeldt-Jakob disease based on molecular and phenotypic analysis of 300 subjects. Ann Neurol1999; 46: 224–33 (10.1002/1531-8249(199908)46:2<224::AID-ANA12>3.0.CO;2-W)
Asante EA, Linehan JM, Desbruslais M et al. BSE prions propagate as either variant CJD-like or sporadic CJD-like prion strains in transgenic mice expressing human prion protein. EMBO J2002; 21: 6358–66 (10.1093/emboj/cdf653)
Hill AF, Desbruslais M, Joiner S, Sidle KCL, Gowland I, Collinge J. The same prion strain causes vCJD and BSE. Nature1997; 389: 448–50 (10.1038/38925)
Pattison IH. Experiments with scrapie with special reference to the nature of the agent and the pathology of the disease. In: Gajdusek CJ, Gibbs CJ, Alpers MP (eds) Slow, Latent and Temperate Virus Infections, NINDB Monograph 2. Washington, DC: US Government Printing, 1965; 249–57
Scott M, Foster D, Mirenda C et al. Transgenic mice expressing hamster prion protein produce species-specific scrapie infectivity and amyloid plaques. Cell1989; 59: 847–57 (10.1016/0092-8674(89)90608-9)
Collinge J, Palmer MS, Sidle KCL et al. Unaltered susceptibility to BSE in transgenic mice expressing human prion protein. Nature1995; 378: 779–83 (10.1038/378779a0)
Bruce ME, Will RG, Ironside JW et al. Transmissions to mice indicate that ‘new variant’ CJD is caused by the BSE agent. Nature1997; 389: 498–501 (10.1038/39057)
Collinge J. Variant Creutzfeldt-Jakob disease. Lancet1999; 354: 317–23 (10.1016/S0140-6736(99)05128-4)
Dickinson AG, Fraser H, Outram GW. Scrapie incubation time can exceed natural lifespan. Nature1975; 256: 732–3 (10.1038/256732a0)
Hill AF, Joiner S, Linehan J, Desbruslais M, Lantos PL, Collinge J. Species barrier independent prion replication in apparently resistant species. Proc Natl Acad Sci USA2000; 97: 10248–53 (10.1073/pnas.97.18.10248)
Race R, Raines A, Raymond GJ, Caughey B, Chesebro B. Long-term subclinical carrier state precedes scrapie replication and adaptation in a resistant species: Analogies to bovine spongiform encephalopathy and variant Creutzfeldt-Jakob disease in humans. J Virol2001; 75: 10106–12 (10.1128/JVI.75.21.10106-10112.2001)
Klein M, Frigg R, Raeber A et al. PrP expression in B-lymphocytes is not required for prion neuroinvasion. Nat Med1998; 4: 1429–33 (10.1038/4022)
Frigg R, Klein MA, Hegyi I, Zinkernagel RM, Aguzzi A. Scrapie pathogenesis in subclinically infected B-cell-deficient mice. J Virol1999; 73: 9584–8 (10.1128/JVI.73.11.9584-9588.1999)
Thackray AM, Klein MA, Aguzzi A, Bujdoso R. Chronic subclinical prion disease induced by low-dose inoculum. J Virol2002; 76: 2510–7 (10.1128/jvi.76.5.2510-2517.2002)
Brown P, Preece M, Brandel JP et al. Iatrogenic Creutzfeldt-Jakob disease at the millennium. Neurology2000; 55: 1075–81 (10.1212/WNL.55.8.1075)
Hill AF, Butterworth RJ, Joiner S et al. Investigation of variant Creutzfeldt-Jakob disease and other human prion diseases with tonsil biopsy samples. Lancet1999; 353: 183–9 (10.1016/S0140-6736(98)12075-5)
Wadsworth JDF, Joiner S, Hill AF et al. Tissue distribution of protease resistant prion protein in variant CJD using a highly sensitive immuno-blotting assay. Lancet2001; 358: 171–80 (10.1016/S0140-6736(01)05403-4)
Brown P, Gibbs CJJ, Rodgers Johnson P et al. Human spongiform encephalopathy: the National Institutes of Health series of 300 cases of experimentally transmitted disease. Ann Neurol1994; 35: 513–29 (10.1002/ana.410350504)
Hill AF, Zeidler M, Ironside J, Collinge J. Diagnosis of new variant Creutzfeldt-Jakob disease by tonsil biopsy. Lancet1997; 349: 99–100 (10.1016/S0140-6736(97)24002-X)
Schaller O, Fatzer R, Stack M et al. Validation of a Western immunoblotting procedure for bovine PrPSc detection and its use as a rapid surveillance method for the diagnosis of bovine spongiform encephalopathy (BSE). Acta Neuropathol1999; 98: 437–43 (10.1007/s004010051106)
Schulz-Schaeffer WJ, Tschüke S, Kranefuss N et al. The paraffin-embedded tissue blot detects PrPSc early in the incubation time in prion diseases. Am J Pathol2000; 156: 51–6 (10.1016/S0002-9440(10)64705-0)
Büeler H, Raeber A, Sailer A, Fischer M, Aguzzi A, Weissmann C. High prion and PrPSc levels but delayed onset of disease in scrapie-inoculated mice heterozygous for a disrupted PrP gene. Mol Med1994; 1: 19–30 (10.1007/BF03403528)
Brandner S, Isenmann S, Raeber A et al. Normal host prion protein necessary for scrapie-induced neurotoxicity. Nature1996; 379: 339–43 (10.1038/379339a0)
Collinge J, Owen F, Poulter M et al. Prion dementia without characteristic pathology. Lancet1990; 336: 7–9 (10.1016/0140-6736(90)91518-F)
Medori R, Montagna P, Tritschler HJ et al. Fatal familial insomnia: a second kindred with mutation of prion protein gene at codon 178. Neurology1992; 42: 669–70 (10.1212/WNL.42.3.669)
Collinge J, Palmer MS, Sidle KCL et al. Transmission of fatal familial insomnia to laboratory animals. Lancet1995; 346: 569–70 (10.1016/S0140-6736(95)91405-6)
Lasmezas CI, Deslys J-P, Robain O, et al. Transmission of the BSE agent to mice in the absence of detectable abnormal prion protein. Science1997; 275: 402–5 (10.1126/science.275.5298.402)
Weissmann C. A ‘unified theory’ of prion propagation. Nature1991; 352: 679–83 (10.1038/352679a0)
Zlotnik I. Observations on the experimental transmission of scrapie of various origins to laboratory animals. In: Gajdusek CJ, Gibbs CJ, Alpers MP (eds) Slow latent and temperate virus infections. Washington DC:Us Government Printing, 1965:237–48
Kimberlin RH, Walker CA. Evidence that the transmission of one source of scrapie agent to hamsters involves separation of agent strains from a mixture. J Gen Virol1978; 39: 487–496 (10.1099/0022-1317-39-3-487)
Race R, Chesebro B. Scrapie infectivity found in resistant species. Nature1998; 392: 770 (10.1038/33834)

Dates

Type	When
Created	21 years, 11 months ago (Oct. 1, 2003, 4:32 p.m.)
Deposited	2 years, 4 months ago (April 26, 2023, 9:24 p.m.)
Indexed	1 week, 6 days ago (Aug. 23, 2025, 12:59 a.m.)
Issued	22 years, 3 months ago (June 1, 2003)
Published	22 years, 3 months ago (June 1, 2003)
Published Online	22 years, 3 months ago (June 1, 2003)
Published Print	22 years, 3 months ago (June 1, 2003)

Funders 0

None

BibTeX

@article{Hill_2003, title={Subclinical prion infection in humans and animals}, volume={66}, ISSN={0007-1420}, url={http://dx.doi.org/10.1093/bmb/66.1.161}, DOI={10.1093/bmb/66.1.161}, number={1}, journal={British Medical Bulletin}, publisher={Oxford University Press (OUP)}, author={Hill, Andrew F and Collinge, John}, year={2003}, month=jun, pages={161–170} }

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    },
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