DOI: 10.1093/bioinformatics/17.3.284. ASEdb: a database of alanine mutations and their effects on the free energy of binding in protein interactions

ASEdb: a database of alanine mutations and their effects on the free energy of binding in protein interactions

10.1093/bioinformatics/17.3.284

Crossref journal-article

Oxford University Press (OUP)

Bioinformatics (286)

Abstract

Abstract Summary: The Alanine Scanning Energetics database (ASEdb) is a searchable database of single alanine mutations in protein–protein, protein–nucleic acid, and protein–small molecule interactions for which binding affinities have been experimentally determined. In cases where structures are available, it contains surface areas of the mutated side chain and links to the PDB entries. It is useful for studying the contribution of single amino acids to the energetics of protein interactions, and can be updated by researchers as new data are generated. Availability: ASEdb is accessible on the Web at http://www.asedb.org Contact: thorn@itsa.ucsf.edu * To whom correspondence should be addressed.

Bibliography

Thorn, K. S., & Bogan, A. A. (2001). ASEdb: a database of alanine mutations and their effects on the free energy of binding in protein interactions. Bioinformatics, 17(3), 284â285.

Authors 2

Kurt S. Thorn (first)
Andrew A. Bogan (additional)

References 0 Referenced 338

None

Dates

Type	When
Created	23 years, 1 month ago (July 26, 2002, 6:49 p.m.)
Deposited	2 years, 7 months ago (Jan. 24, 2023, 1:33 a.m.)
Indexed	3 weeks, 6 days ago (July 30, 2025, 11:31 a.m.)
Issued	24 years, 5 months ago (March 1, 2001)
Published	24 years, 5 months ago (March 1, 2001)
Published Online	24 years, 5 months ago (March 1, 2001)
Published Print	24 years, 5 months ago (March 1, 2001)

Funders 0

None

BibTeX

@article{Thorn_2001, title={ASEdb: a database of alanine mutations and their effects on the free energy of binding in protein interactions}, volume={17}, ISSN={1367-4803}, url={http://dx.doi.org/10.1093/bioinformatics/17.3.284}, DOI={10.1093/bioinformatics/17.3.284}, number={3}, journal={Bioinformatics}, publisher={Oxford University Press (OUP)}, author={Thorn, Kurt S. and Bogan, Andrew A.}, year={2001}, month=mar, pages={284–285} }

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