DOI: 10.1091/mbc.6.3.297. NudF, a nuclear migration gene in Aspergillus nidulans, is similar to the human LIS-1 gene required for neuronal migration.

NudF, a nuclear migration gene in Aspergillus nidulans, is similar to the human LIS-1 gene required for neuronal migration.

10.1091/mbc.6.3.297

Crossref journal-article

American Society for Cell Biology (ASCB)

Molecular Biology of the Cell (1076)

Abstract

During a study of the genetics of nuclear migration in the filamentous fungus Aspergillus nidulans, we cloned a gene, nudF, which is required for nuclear migration during vegetative growth as well as development. The NUDF protein level is controlled by another protein NUDC, and extra copies of the nudF gene can suppress the nudC3 mutation. nudF encodes a protein with 42% sequence identity to the human LIS-1 (Miller-Dieker lissencephaly-1) gene, which is required for proper neuronal migration during brain development. This strong similarity suggests that the LIS-1 gene product may have a function similar to that of NUDF and supports previous findings to suggest that nuclear migration may play a role in neuronal migration.

Bibliography

Xiang, X., Osmani, A. H., Osmani, S. A., Xin, M., & Morris, N. R. (1995). NudF, a nuclear migration gene in Aspergillus nidulans, is similar to the human LIS-1 gene required for neuronal migration. Molecular Biology of the Cell, 6(3), 297â310.

Authors 5

X Xiang (first)
A H Osmani (additional)
S A Osmani (additional)
M Xin (additional)
N R Morris (additional)

References 0 Referenced 282

None

Dates

Type	When
Created	12 years ago (Aug. 16, 2013, 3:08 p.m.)
Deposited	6 years, 1 month ago (July 14, 2019, 9 a.m.)
Indexed	3 weeks, 6 days ago (Aug. 6, 2025, 9:51 a.m.)
Issued	30 years, 6 months ago (March 1, 1995)
Published	30 years, 6 months ago (March 1, 1995)
Published Print	30 years, 6 months ago (March 1, 1995)

Funders 0

None

BibTeX

@article{Xiang_1995, title={NudF, a nuclear migration gene in Aspergillus nidulans, is similar to the human LIS-1 gene required for neuronal migration.}, volume={6}, ISSN={1939-4586}, url={http://dx.doi.org/10.1091/mbc.6.3.297}, DOI={10.1091/mbc.6.3.297}, number={3}, journal={Molecular Biology of the Cell}, publisher={American Society for Cell Biology (ASCB)}, author={Xiang, X and Osmani, A H and Osmani, S A and Xin, M and Morris, N R}, year={1995}, month=mar, pages={297–310} }

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