DOI: 10.1086/302746. ATM-Heterozygous Germline Mutations Contribute to Breast Cancer

ATM-Heterozygous Germline Mutations Contribute to Breast Cancer–Susceptibility

10.1086/302746

Crossref journal-article

Elsevier BV

The American Journal of Human Genetics (78)

Authors 10

Annegien Broeks (first)
Jos H.M. Urbanus (additional)
Arno N. Floore (additional)
Ellen C. Dahler (additional)
Jan G.M. Klijn (additional)
Emiel J. Th. Rutgers (additional)
Peter Devilee (additional)
Nicola S. Russell (additional)
Flora E. van Leeuwen (additional)
Laura J. van't Veer (additional)

References 24 Referenced 177

10.1016/S0165-4608(96)00328-7 / Cancer Genet Cytogenet / Molecular genotyping shows that ataxia-telangiectasia heterozygotes are predisposed to breast cancer by Athma (1996)
10.1002/(SICI)1098-1004(1998)12:5<330::AID-HUMU6>3.0.CO;2-H / Hum Mut / ATM germline mutations in classical ataxia-telangiectasia patients in the Dutch population by Broeks (1998)
{'key': '10.1086/302746_bib3', 'first-page': '1376', 'article-title': 'The role of ataxia-telangiectasia heterozygotes in familial breast cancer', 'volume': '58', 'author': 'Chen', 'year': '1998', 'journal-title': 'Cancer Res'} / Cancer Res / The role of ataxia-telangiectasia heterozygotes in familial breast cancer by Chen (1998)
10.1080/09553009414552011 / Int J Radiat Biol Suppl / Cancer risks in A-T heterozygotes by Easton (1994)
10.1038/ng0397-307 / Nat Genet / Heterozygous ATM mutations do not contribute to early onset of breast cancer by FitzGerald (1997)
10.1097/00005792-199103000-00003 / Medicine / Ataxia-telangiectasia: an interdisciplinary approach to pathogenesis by Gatti (1991)
10.1086/301755 / Am J Hum Genet / Genotype-phenotype relationships in ataxia-telangiectasia and variants by Gilad (1998)
10.1038/sj.bjc.6690209 / Br J Cancer / Risk of breast cancer and other cancers in heterozygotes for ataxia-telangiectasia by Inskip (1999)
10.1038/sj.bjc.6690460 / Br J Cancer / Breast cancer risk in ataxia-telangiectasia (A-T) heterozygotes: haplotype study in French A-T families by Janin (1999)
10.1002/(SICI)1098-2264(199907)25:3<212::AID-GCC3>3.0.CO;2-G / Genes Chromosom Cancer / Loss of heterozygosity at 11q23.1 and survival in breast cancer: results of a large European study by Laake (1999)
10.1002/(SICI)1098-2264(199703)18:3<175::AID-GCC4>3.0.CO;2-Z / Genes Chromosom Cancer / Loss of heterozygosity at 11q23.1 in breast carcinomas: indication for involvement of a gene distal and close to ATM by Laake (1997)
10.1016/S0952-7915(96)80030-6 / Curr Opin Immunol / Ataxia-telangiectasia: a multifaceted genetic disorder associated with defective signal transduction by Lavin (1996)
10.1146/annurev.immunol.15.1.177 / Annu Rev Immunol / The genetic defect in ataxia-telangiectasia by Lavin (1997)
{'key': '10.1086/302746_bib14', 'first-page': '3725', 'article-title': 'Enhanced radiosensitivity of cultured fibroblasts from ataxia-telangiectasia heterozygotes manifested by defective colony- forming ability and reduced DNA repair replication after hypoxic gamma irradiation', 'volume': '39', 'author': 'Paterson', 'year': '1979', 'journal-title': 'Cancer Res'} / Cancer Res / Enhanced radiosensitivity of cultured fibroblasts from ataxia-telangiectasia heterozygotes manifested by defective colony- forming ability and reduced DNA repair replication after hypoxic gamma irradiation by Paterson (1979)
10.1101/gr.7.6.592 / Genome Res / Ataxia-telangiectasia locus: sequence analysis of 184 kb of human genomic DNA containing the entire ATM gene by Platzer (1997)
{'key': '10.1086/302746_bib16', 'series-title': 'Molecular cloning: a laboratory manuel', 'author': 'Sambrook', 'year': '1989'} / Molecular cloning: a laboratory manuel by Sambrook (1989)
10.1093/hmg/8.1.69 / Hum Mol Genet / Characterization of ATM gene mutations in 66 ataxia-telangiectasia families by Sandoval (1999)
10.1126/science.7792600 / Science / A single ataxia-telangiectasia gene with a product similar to PI-3 kinase by Savitsky (1995)
{'key': '10.1086/302746_bib19', 'series-title': 'Hereditary neuropathies and spinocerebellar atrophies', 'first-page': '347', 'article-title': 'Ataxia-telangiectasia', 'author': 'Segdwick', 'year': '1991'} / Hereditary neuropathies and spinocerebellar atrophies / Ataxia-telangiectasia by Segdwick (1991)
10.1159/000472285 / Eur J Hum Genet / Ataxia-telangiectasia: closer to unravelling the mystery by Shiloh (1995)
10.1056/NEJM199112263252602 / N Engl J Med / Incidence of cancer in 161 families affected by ataxia-telangiectasia by Swift (1991)
10.1056/NEJM198705213162101 / N Engl J Med / Breast and other cancers in families with ataxia-telangiectasia by Swift (1987)
10.1086/302418 / Am J Hum Genet / Splicing defects in the Ataxia-telangiectasia gene, ATM: underlying mutations and consequences by Teraoka (1999)
10.1080/09553009514551101 / Int J Radiat Biol / A comparison of the radiosensitivity of lymphocytes from normal donors, cancer patients, individuals with ataxia-telangiectasia (A-T) and A-T heterozygotes by West (1995)

Dates

Type	When
Created	23 years, 1 month ago (July 26, 2002, 10:47 a.m.)
Deposited	6 years, 4 months ago (April 11, 2019, 9:21 a.m.)
Indexed	1 month, 1 week ago (July 23, 2025, 8:55 a.m.)
Issued	25 years, 7 months ago (Feb. 1, 2000)
Published	25 years, 7 months ago (Feb. 1, 2000)
Published Print	25 years, 7 months ago (Feb. 1, 2000)

Funders 0

None

BibTeX

@article{Broeks_2000, title={ATM-Heterozygous Germline Mutations Contribute to Breast Cancer–Susceptibility}, volume={66}, ISSN={0002-9297}, url={http://dx.doi.org/10.1086/302746}, DOI={10.1086/302746}, number={2}, journal={The American Journal of Human Genetics}, publisher={Elsevier BV}, author={Broeks, Annegien and Urbanus, Jos H.M. and Floore, Arno N. and Dahler, Ellen C. and Klijn, Jan G.M. and Rutgers, Emiel J. Th. and Devilee, Peter and Russell, Nicola S. and van Leeuwen, Flora E. and van’t Veer, Laura J.}, year={2000}, month=feb, pages={494–500} }

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