DOI: 10.1086/301903. Frequency and Carrier Risk Associated with Common BRCA1 and BRCA2 Mutations in Ashkenazi Jewish Breast Cancer Patients

Frequency and Carrier Risk Associated with Common BRCA1 and BRCA2 Mutations in Ashkenazi Jewish Breast Cancer Patients

10.1086/301903

Crossref journal-article

Elsevier BV

The American Journal of Human Genetics (78)

Bibliography

Fodor, F. H., Weston, A., Bleiweiss, I. J., McCurdy, L. D., Walsh, M. M., Tartter, P. I., Brower, S. T., & Eng, C. M. (1998). Frequency and Carrier Risk Associated with Common BRCA1 and BRCA2 Mutations in Ashkenazi Jewish Breast Cancer Patients. The American Journal of Human Genetics, 63(1), 45â51.

Authors 8

Flora H. Fodor (first)
Ainsley Weston (additional)
Ira J. Bleiweiss (additional)
Leslie D. McCurdy (additional)
Mary M. Walsh (additional)
Paul I. Tartter (additional)
Steven T. Brower (additional)
Christine M. Eng (additional)

References 29 Referenced 149

{'key': '10.1086/301903_bib1', 'first-page': '505', 'article-title': 'The founder mutations 185delAG and 5382insC in BRCA1 and 6174delT in BRCA2 appear in 60% of ovarian cancer and 30% of early-onset breast cancer patients among Ashkenazi women', 'volume': '60', 'author': 'Abeliovich', 'year': '1997', 'journal-title': 'Am J Hum Genet'} / Am J Hum Genet / The founder mutations 185delAG and 5382insC in BRCA1 and 6174delT in BRCA2 appear in 60% of ovarian cancer and 30% of early-onset breast cancer patients among Ashkenazi women by Abeliovich (1997)
10.1016/S0140-6736(95)91310-6 / Lancet / Histoprognostic grade in tumours from families with hereditary predisposition to breast cancer by Bignon (1995)
{'key': '10.1086/301903_bib3', 'first-page': '232', 'article-title': 'Genetic analysis of breast cancer in the Cancer and Steroid Hormone Study', 'volume': '48', 'author': 'Claus', 'year': '1991', 'journal-title': 'Am J Hum Genet'} / Am J Hum Genet / Genetic analysis of breast cancer in the Cancer and Steroid Hormone Study by Claus (1991)
{'key': '10.1086/301903_bib4', 'first-page': '265', 'article-title': 'Breast Cancer Linkage Consortium Breast and ovarian cancer incidence in BRCA1-mutation carriers', 'volume': '56', 'author': 'Easton', 'year': '1995', 'journal-title': 'Am J Hum Genet'} / Am J Hum Genet / Breast Cancer Linkage Consortium Breast and ovarian cancer incidence in BRCA1-mutation carriers by Easton (1995)
10.1016/S0140-6736(96)91485-3 / Lancet / Jewish religion and risk of breast cancer by Egan (1996)
{'key': '10.1086/301903_bib6', 'first-page': '471', 'article-title': 'Germ line mutation at BRCA1 affects the histoprognostic grade in hereditary breast cancer', 'volume': '56', 'author': 'Eisinger', 'year': '1996', 'journal-title': 'Cancer Res'} / Cancer Res / Germ line mutation at BRCA1 affects the histoprognostic grade in hereditary breast cancer by Eisinger (1996)
10.1056/NEJM199601183340302 / N Engl J Med / Germ-line BRCA1 mutations in Jewish and non-Jewish women with early-onset breast cancer by FitzGerald (1996)
10.1016/S0140-6736(94)91578-4 / Lancet / Risks of cancer in BRCA1 mutation carriers: Breast Cancer Linkage Consortium by Ford (1994)
10.1038/ng1294-399 / Nat Genet / Confirmation of BRCA1 by analysis of germline mutations linked to breast and ovarian cancer in ten families by Friedman (1994)
{'key': '10.1086/301903_bib10', 'first-page': '1284', 'article-title': 'Novel inherited mutations and variable expressivity of BRCA1 alleles, including the founder mutation 185delAG in Ashkenazi Jewish families', 'volume': '57', 'author': 'Friedman', 'year': '1995', 'journal-title': 'Am J Hum Genet'} / Am J Hum Genet / Novel inherited mutations and variable expressivity of BRCA1 alleles, including the founder mutation 185delAG in Ashkenazi Jewish families by Friedman (1995)
{'key': '10.1086/301903_bib11', 'first-page': '451', 'article-title': 'UKCCCR Familial Ovarian Cancer Study Group Rapid detection of regionally clustered germ-line BRCA1 mutations by multiplex heteroduplex analysis', 'volume': '58', 'author': 'Gayther', 'year': '1996', 'journal-title': 'Am J Hum Genet'} / Am J Hum Genet / UKCCCR Familial Ovarian Cancer Study Group Rapid detection of regionally clustered germ-line BRCA1 mutations by multiplex heteroduplex analysis by Gayther (1996)
10.1001/jama.1995.03520310075033 / JAMA / Assessment and counseling for women with a family history of breast cancer by Hoskins (1995)
10.1002/(SICI)1097-0142(19960215)77:4<697::AID-CNCR16>3.0.CO;2-W / Cancer / Hereditary breast cancer: pathobiology, prognosis, and BRCA1 and BRCA2 gene linkage by Marcus (1996)
10.1038/ng0596-126 / Nat Genet / Recurrent BRCA2 6174delT mutations in Ashkenazi Jewish women affected by breast cancer by Neuhausen (1996)
10.1038/ng1096-188 / Nat Genet / The carrier frequency of the BRCA2 6174delT mutation among Ashkenazi Jewish individuals is approximately 1% by Oddoux (1996)
10.1016/S0140-6736(96)91484-1 / Lancet / Germline BRCA1 185delAG mutations in Jewish women with breast cancer by Offit (1996)
10.3322/canjclin.47.1.5 / CA Cancer J Clin / Cancer statistics, 1997 by Parker (1997)
10.1038/ng1096-185 / Nat Genet / Ashkenazi Jewish population frequencies for common mutations in BRCA1 and BRCA2 by Roa (1996)
10.1136/jcp.47.4.318 / J Clin Pathol / Rapid techniques for DNA extraction from routinely processed archival tissue for use in PCR by Sepp (1994)
10.1001/jama.1997.03550150046034 / JAMA / BRCA1 sequence analysis in women at high risk for susceptibility mutations by Shattuck-Eidens (1997)
10.1101/gr.5.5.488 / Genome Res / A simplified procedure for developing multiplex PCRs by Shuber (1995)
10.1038/ng1294-392 / Nat Genet / Common origins of BRCA1 mutations in Canadian breast and ovarian cancer families by Simard (1994)
10.1093/hmg/5.Supplement_1.1515 / Hum Mol Genet / Recent advances in understanding of genetic susceptibility to breast cancer by Stratton (1996)
10.1038/ng1095-198 / Nat Genet / The carrier frequency of the BRCA1 185delAG mutation is approximately 1 percent in Ashkenazi Jewish individuals by Struewing (1995)
10.1056/NEJM199705153362001 / N Engl J Med / The risk of cancer associated with specific mutations of BRCA1 and BRCA2 among Ashkenazi Jews by Struewing (1997)
10.1038/ng0396-333 / Nat Genet / The complete BRCA2 gene and mutations in chromosome 13q-linked kindreds by Tavtigian (1996)
{'key': '10.1086/301903_bib28', 'first-page': '189', 'article-title': 'BRCA1 mutations in Ashkenazi Jewish women', 'volume': '57', 'author': 'Tonin', 'year': '1995', 'journal-title': 'Am J Hum Genet'} / Am J Hum Genet / BRCA1 mutations in Ashkenazi Jewish women by Tonin (1995)
10.1038/nm1196-1179 / Nat Med / Frequency of recurrent BRCA1 and BRCA2 mutations in Ashkenazi Jewish breast cancer families by Tonin (1996)
10.1126/science.8091231 / Science / Localization of breast cancer susceptibility gene, BRCA2, to chromosome 13q12-13 by Wooster (1994)

Dates

Type	When
Created	23 years, 1 month ago (July 26, 2002, 2:47 p.m.)
Deposited	6 years, 4 months ago (April 11, 2019, 1:28 p.m.)
Indexed	3 weeks, 5 days ago (Aug. 7, 2025, 5:14 p.m.)
Issued	27 years, 2 months ago (July 1, 1998)
Published	27 years, 2 months ago (July 1, 1998)
Published Print	27 years, 2 months ago (July 1, 1998)

Funders 0

None

BibTeX

@article{Fodor_1998, title={Frequency and Carrier Risk Associated with Common BRCA1 and BRCA2 Mutations in Ashkenazi Jewish Breast Cancer Patients}, volume={63}, ISSN={0002-9297}, url={http://dx.doi.org/10.1086/301903}, DOI={10.1086/301903}, number={1}, journal={The American Journal of Human Genetics}, publisher={Elsevier BV}, author={Fodor, Flora H. and Weston, Ainsley and Bleiweiss, Ira J. and McCurdy, Leslie D. and Walsh, Mary M. and Tartter, Paul I. and Brower, Steven T. and Eng, Christine M.}, year={1998}, month=jul, pages={45–51} }

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