DOI: 10.1084/jem.77.4.345. ISOLATION OF CHROMATIN THREADS FROM THE RESTING NUCLEUS OF LEUKEMIC CELLS

ISOLATION OF CHROMATIN THREADS FROM THE RESTING NUCLEUS OF LEUKEMIC CELLS

10.1084/jem.77.4.345

Crossref journal-article

Rockefeller University Press

Journal of Experimental Medicine (291)

Abstract

1. A method for the separation of chromatin threads from the resting nucleus of leukemic cells has been described. 2. The isolation of the chromatin strands was accomplished by purely mechanical means, and the separation, including extraction and purification in the centrifuge, required only about 1 hour. 3. Evidence is presented to show that the chromatin strands are morphologically related to the chromosomes, if not identical. 4. It seems probable that, by the present technique, chromatin strands can be obtained from different mammalian tissues for direct microscopical examination and biochemical analysis.

Bibliography

Claude, A., & Potter, J. S. (1943). ISOLATION OF CHROMATIN THREADS FROM THE RESTING NUCLEUS OF LEUKEMIC CELLS. Journal of Experimental Medicine, 77(4), 345â354.

Authors 2

Albert Claude (first)
James S. Potter (additional)

References 0 Referenced 57

None

Dates

Type	When
Created	21 years, 2 months ago (June 21, 2004, 7:43 p.m.)
Deposited	4 years, 11 months ago (Oct. 3, 2020, 9:39 a.m.)
Indexed	3 days, 7 hours ago (Sept. 4, 2025, 9:50 a.m.)
Issued	82 years, 5 months ago (April 1, 1943)
Published	82 years, 5 months ago (April 1, 1943)
Published Online	82 years, 5 months ago (April 1, 1943)
Published Print	82 years, 5 months ago (April 1, 1943)

Funders 0

None

BibTeX

@article{Claude_1943, title={ISOLATION OF CHROMATIN THREADS FROM THE RESTING NUCLEUS OF LEUKEMIC CELLS}, volume={77}, ISSN={0022-1007}, url={http://dx.doi.org/10.1084/jem.77.4.345}, DOI={10.1084/jem.77.4.345}, number={4}, journal={Journal of Experimental Medicine}, publisher={Rockefeller University Press}, author={Claude, Albert and Potter, James S.}, year={1943}, month=apr, pages={345–354} }

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