DOI: 10.1084/jem.167.2.652. Transfected plasmacytoma cells do not transport the membrane form of IgM to the cell surface.

Transfected plasmacytoma cells do not transport the membrane form of IgM to the cell surface.

10.1084/jem.167.2.652

Crossref journal-article

Rockefeller University Press

The Journal of experimental medicine (291)

Abstract

Expression vectors coding for membrane-bound IgM antibodies were introduced into myeloma and B lymphoma cells. Only the lymphoma but not the myeloma cells were able to express the antibodies on the cell surface, although in both cases, complete antibodies were assembled intracellularly. In myeloma cells, the Ig molecules did not reach the Golgi compartment. Thus, the intracellular transport of membrane-bound antibodies is controlled in the B cell lineages in a developmentally ordered fashion.

Bibliography

Hombach, J., Sablitzky, F., Rajewsky, K., & Reth, M. (1988). Transfected plasmacytoma cells do not transport the membrane form of IgM to the cell surface. The Journal of Experimental Medicine, 167(2), 652â657.

Authors 4

J Hombach (first)
F Sablitzky (additional)
K Rajewsky (additional)
M Reth (additional)

References 0 Referenced 41

None

Dates

Type	When
Created	21 years, 2 months ago (June 24, 2004, 3:56 a.m.)
Deposited	2 years, 1 month ago (July 24, 2023, 9:18 p.m.)
Indexed	4 months, 4 weeks ago (March 29, 2025, 3:31 p.m.)
Issued	37 years, 6 months ago (Feb. 1, 1988)
Published	37 years, 6 months ago (Feb. 1, 1988)
Published Online	37 years, 6 months ago (Feb. 1, 1988)
Published Print	37 years, 6 months ago (Feb. 1, 1988)

Funders 0

None

BibTeX

@article{Hombach_1988, title={Transfected plasmacytoma cells do not transport the membrane form of IgM to the cell surface.}, volume={167}, ISSN={1540-9538}, url={http://dx.doi.org/10.1084/jem.167.2.652}, DOI={10.1084/jem.167.2.652}, number={2}, journal={The Journal of experimental medicine}, publisher={Rockefeller University Press}, author={Hombach, J and Sablitzky, F and Rajewsky, K and Reth, M}, year={1988}, month=feb, pages={652–657} }

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