Abstract
A multivalent lacto-N-fucopentaose (LNFP) III-lysyllysine conjugate was observed to decompact preimplantation mouse embryos. Decompaction was not obtained with free oligosaccharides (LNFP II and III), nor with multivalent LNFP II-lysyllysine or chitotriose-lysyllysine conjugates. These results suggest a role for X hapten recognition during compaction and suggest further that X hapten valency may play a key role in modulating this developmental process.
Dates
Type | When |
---|---|
Created | 21 years, 2 months ago (June 23, 2004, 5 p.m.) |
Deposited | 2 years, 1 month ago (July 24, 2023, 8:52 p.m.) |
Indexed | 3 weeks, 4 days ago (Aug. 7, 2025, 4:53 a.m.) |
Issued | 40 years, 10 months ago (Nov. 1, 1984) |
Published | 40 years, 10 months ago (Nov. 1, 1984) |
Published Online | 40 years, 10 months ago (Nov. 1, 1984) |
Published Print | 40 years, 10 months ago (Nov. 1, 1984) |
@article{Fenderson_1984, title={A multivalent lacto-N-fucopentaose III-lysyllysine conjugate decompacts preimplantation mouse embryos, while the free oligosaccharide is ineffective.}, volume={160}, ISSN={1540-9538}, url={http://dx.doi.org/10.1084/jem.160.5.1591}, DOI={10.1084/jem.160.5.1591}, number={5}, journal={The Journal of experimental medicine}, publisher={Rockefeller University Press}, author={Fenderson, B A and Zehavi, U and Hakomori, S}, year={1984}, month=nov, pages={1591–1596} }