Abstract
Outer thymic cortical large lymphocytes were labeled by transcapsular administration of tritiated thymidine. By 2–4 days after labeling, small and medium labeled lymphocyte descendants were found throughout the cortex and in the medulla. The labeled cortical lymphocytes undergo pycnosis after parenteral administration of hydrocortisone 24 h previously, but their (labeled) medullary descendants do not. In addition, parenteral administration of hydrocortisone at the time of surface labeling results in the absence of the appearance of labeled medullary descendants.
Dates
Type | When |
---|---|
Created | 21 years, 2 months ago (June 23, 2004, 7:23 p.m.) |
Deposited | 2 years, 1 month ago (July 24, 2023, 5:04 p.m.) |
Indexed | 5 months ago (March 31, 2025, 8:43 a.m.) |
Issued | 52 years, 6 months ago (Feb. 1, 1973) |
Published | 52 years, 6 months ago (Feb. 1, 1973) |
Published Online | 52 years, 6 months ago (Feb. 1, 1973) |
Published Print | 52 years, 6 months ago (Feb. 1, 1973) |
@article{Weissman_1973, title={THYMUS CELL MATURATION}, volume={137}, ISSN={0022-1007}, url={http://dx.doi.org/10.1084/jem.137.2.504}, DOI={10.1084/jem.137.2.504}, number={2}, journal={The Journal of Experimental Medicine}, publisher={Rockefeller University Press}, author={Weissman, Irving L.}, year={1973}, month=feb, pages={504–510} }