Abstract
The possibility that a rat alloantiserum DA anti-Lewis possesses similar recognition structures for Lewis transplantation antigens, as do DA immunocompetent cells, was investigated by raising an antiserum against this alloantiserum in (Lewis x DA)F1 hosts. This antiserum, as well as one provoked by injecting DA lymphoid cells, was active against recognition structures for Lewis antigens of DA immunocompetent cells. The anti-(DA anti-Lewis) antiserum displayed the same degree of specificity as was found previously for anti-recognition structure sera prepared by injecting parental strain lymphoid cells into F1 hosts. Since the activities of antisera raised against cell-bound receptors or against the antigen-binding region of an immunoglobulin were indistinguishable, it was concluded that the functional part of cell-associated receptors might be structurally similar to the variable portion of an immunoglobulin.
Dates
Type | When |
---|---|
Created | 21 years, 2 months ago (June 23, 2004, 7:23 p.m.) |
Deposited | 2 years, 1 month ago (July 24, 2023, 4:48 p.m.) |
Indexed | 4 months, 4 weeks ago (April 8, 2025, 5:39 p.m.) |
Issued | 53 years, 10 months ago (Nov. 1, 1971) |
Published | 53 years, 10 months ago (Nov. 1, 1971) |
Published Online | 53 years, 10 months ago (Nov. 1, 1971) |
Published Print | 53 years, 10 months ago (Nov. 1, 1971) |
@article{Ramseier_1971, title={CELLULAR RECEPTORS}, volume={134}, ISSN={0022-1007}, url={http://dx.doi.org/10.1084/jem.134.5.1083}, DOI={10.1084/jem.134.5.1083}, number={5}, journal={The Journal of Experimental Medicine}, publisher={Rockefeller University Press}, author={Ramseier, Hansruedy and Lindenmann, Jean}, year={1971}, month=nov, pages={1083–1094} }