Abstract
Human and animal solid tumors elaborate a factor which is mitogenic to capillary endothelial cells. This factor has been called tumor-angiogenesis factor. The important components of TAF are RNA and protein. It is suggested that blockade of this factor (inhibition of angiogenesis) might arrest solid tumors at a tiny diameter of a few millimeters.
Dates
Type | When |
---|---|
Created | 21 years, 2 months ago (June 23, 2004, 7:23 p.m.) |
Deposited | 2 years, 1 month ago (July 24, 2023, 4:43 p.m.) |
Indexed | 3 days ago (Aug. 23, 2025, 9:35 p.m.) |
Issued | 54 years, 6 months ago (Feb. 1, 1971) |
Published | 54 years, 6 months ago (Feb. 1, 1971) |
Published Online | 54 years, 6 months ago (Feb. 1, 1971) |
Published Print | 54 years, 6 months ago (Feb. 1, 1971) |
@article{Folkman_1971, title={ISOLATION OF A TUMOR FACTOR RESPONSIBLE FOR ANGIOGENESIS}, volume={133}, ISSN={0022-1007}, url={http://dx.doi.org/10.1084/jem.133.2.275}, DOI={10.1084/jem.133.2.275}, number={2}, journal={The Journal of Experimental Medicine}, publisher={Rockefeller University Press}, author={Folkman, Judah and Merler, Ezio and Abernathy, Charles and Williams, Gretchen}, year={1971}, month=feb, pages={275–288} }