DOI: 10.1084/jem.112.4.687. FACTORS AFFECTING THE CHAIN LENGTH OF GROUP A STREPTOCOCCI

FACTORS AFFECTING THE CHAIN LENGTH OF GROUP A STREPTOCOCCI

10.1084/jem.112.4.687

Crossref journal-article

Rockefeller University Press

The Journal of Experimental Medicine (291)

Abstract

Minute amounts of M protein were detected in culture supernates of virulent Group A streptococci by type-specific inhibition of the long chain and the bactericidal tests for anti-M antibody. The amount of M protein that was detected by the inhibition of these biological systems was less than could be demonstrated by precipitation tests. All strains of streptococci rich in M protein which were studied formed long chains when grown in sufficient concentrations of anti-M antibody. Very low concentrations of anti-M antibody escaped detection by the long chain test when strains of excessive M protein content were employed. Under such conditions the bactericidal test detected anti-M antibody more sensitively than the long chain test owing to the smaller inoculum employed in the former method. The scission of streptococcal chains may be inhibited by union of antibodies with surface antigens other than M protein. Long chains were formed when M-negative, R-positive strains were grown in sera containing anti-R antibody.

Bibliography

Ekstedt, R. D., & Stollerman, G. H. (1960). FACTORS AFFECTING THE CHAIN LENGTH OF GROUP A STREPTOCOCCI. The Journal of Experimental Medicine, 112(4), 687â698.

Authors 2

Richard D. Ekstedt (first)
Gene H. Stollerman (additional)

References 0 Referenced 14

None

Dates

Type	When
Created	21 years, 2 months ago (June 22, 2004, 4:51 p.m.)
Deposited	2 years, 1 month ago (July 24, 2023, 2:53 p.m.)
Indexed	1 year, 1 month ago (July 11, 2024, 10:29 a.m.)
Issued	64 years, 10 months ago (Oct. 1, 1960)
Published	64 years, 10 months ago (Oct. 1, 1960)
Published Online	64 years, 10 months ago (Oct. 1, 1960)
Published Print	64 years, 10 months ago (Oct. 1, 1960)

Funders 0

None

BibTeX

@article{Ekstedt_1960, title={FACTORS AFFECTING THE CHAIN LENGTH OF GROUP A STREPTOCOCCI}, volume={112}, ISSN={0022-1007}, url={http://dx.doi.org/10.1084/jem.112.4.687}, DOI={10.1084/jem.112.4.687}, number={4}, journal={The Journal of Experimental Medicine}, publisher={Rockefeller University Press}, author={Ekstedt, Richard D. and Stollerman, Gene H.}, year={1960}, month=oct, pages={687–698} }

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