Abstract
Decrease in the protease activity of the culture fluid observed at later stages of the antigen-antibody reaction is believed to be due to the release of an inhibitor by the cells. The inhibitor was submitted to partial purification: it is heat-stable, non-precipitated by trichloracetic acid and non-dialyzable. It inhibits certain cellular and tissue proteases and papain but is inactive against trypsin. It is suggested that the balance between protease and anti-protease released may determine the intensity, extent, and duration of certain sensitization phenomena.
Dates
Type | When |
---|---|
Created | 21 years, 2 months ago (June 22, 2004, 4:51 p.m.) |
Deposited | 2 years, 1 month ago (July 24, 2023, 2:51 p.m.) |
Indexed | 1 year, 9 months ago (Nov. 23, 2023, 9:24 a.m.) |
Issued | 65 years ago (Aug. 1, 1960) |
Published | 65 years ago (Aug. 1, 1960) |
Published Online | 65 years ago (Aug. 1, 1960) |
Published Print | 65 years ago (Aug. 1, 1960) |
@article{Tokuda_1960, title={BIOCHEMICAL STUDY OF CELLULAR ANTIGEN-ANTIBODY REACTION IN TISSUE CULTURE}, volume={112}, ISSN={0022-1007}, url={http://dx.doi.org/10.1084/jem.112.2.249}, DOI={10.1084/jem.112.2.249}, number={2}, journal={The Journal of Experimental Medicine}, publisher={Rockefeller University Press}, author={Tokuda, Akira and Hayashi, Hideo and Matsuba, Kinishiro}, year={1960}, month=aug, pages={249–255} }