DOI: 10.1083/jcb.98.6.2250. Stimulated release of histamine by a rat mast cell line is inhibited during mitosis.

Stimulated release of histamine by a rat mast cell line is inhibited during mitosis.

10.1083/jcb.98.6.2250

Crossref journal-article

Rockefeller University Press

The Journal of cell biology (291)

Abstract

Stimulated histamine release was depressed at least tenfold in mitotic 2H3 rat basophilic cells when compared with interphase cells even though both contained comparable amounts of histamine. Antigen stimulation of IgE-sensitized interphase cells initiated an influx of Ca2+ that preceded secretion of histamine and a similar Ca2+ influx occurred in stimulated mitotic cells. This strongly suggests that during mitosis there is a dramatic inhibition of one or more of the steps on the pathway leading from elevated intracellular Ca2+ to the fusion of secretory granules with the plasma membrane.

Bibliography

Hesketh, T. R., Beaven, M. A., Rogers, J., Burke, B., & Warren, G. B. (1984). Stimulated release of histamine by a rat mast cell line is inhibited during mitosis. The Journal of Cell Biology, 98(6), 2250â2254.

Authors 5

T R Hesketh (first)
M A Beaven (additional)
J Rogers (additional)
B Burke (additional)
G B Warren (additional)

References 0 Referenced 32

None

Dates

Type	When
Created	21 years, 3 months ago (May 14, 2004, 7:04 p.m.)
Deposited	2 years, 1 month ago (July 24, 2023, 1:28 p.m.)
Indexed	4 months, 4 weeks ago (March 31, 2025, 2:43 a.m.)
Issued	41 years, 2 months ago (June 1, 1984)
Published	41 years, 2 months ago (June 1, 1984)
Published Online	41 years, 2 months ago (June 1, 1984)
Published Print	41 years, 2 months ago (June 1, 1984)

Funders 0

None

BibTeX

@article{Hesketh_1984, title={Stimulated release of histamine by a rat mast cell line is inhibited during mitosis.}, volume={98}, ISSN={1540-8140}, url={http://dx.doi.org/10.1083/jcb.98.6.2250}, DOI={10.1083/jcb.98.6.2250}, number={6}, journal={The Journal of cell biology}, publisher={Rockefeller University Press}, author={Hesketh, T R and Beaven, M A and Rogers, J and Burke, B and Warren, G B}, year={1984}, month=jun, pages={2250–2254} }

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