DOI: 10.1083/jcb.59.2.267. MICROTUBULES: EVIDENCE FOR 13 PROTOFILAMENTS [Penn]

MICROTUBULES: EVIDENCE FOR 13 PROTOFILAMENTS

10.1083/jcb.59.2.267

Crossref journal-article

Rockefeller University Press

The Journal of Cell Biology (291)

Abstract

When microtubules are fixed in glutaraldehyde in the presence of tannic acid and thin sections cut, the subunit structure of the microtubule is readily observed without the need of image reinforcement. Seven types of microtubules were analyzed: those in the heliozoan axoneme, the mitotic apparatus, the contractile axostyle, repolymerized microtubules derived from the chick brain, the central pair in flagella, and the A tubules of flagella and the basal body. In all cases microtubules were composed of 13 equally spaced protofilaments. The B tubules in flagella and the basal body appear to be composed of 11 subunits. The connections of the B to the A and the C to the B are described. A model of a microtubule is presented.

Bibliography

Tilney, L. G., Bryan, J., Bush, D. J., Fujiwara, K., Mooseker, M. S., Murphy, D. B., & Snyder, D. H. (1973). MICROTUBULES: EVIDENCE FOR 13 PROTOFILAMENTS. The Journal of Cell Biology, 59(2), 267â275.

Authors 7

Lewis G. Tilney (first)
Joseph Bryan (additional)
Doris J. Bush (additional)
Keigi Fujiwara (additional)
Mark S. Mooseker (additional)
Douglas B. Murphy (additional)
Daniel H. Snyder (additional)

References 0 Referenced 357

None

Dates

Type	When
Created	21 years, 3 months ago (May 14, 2004, 6:01 p.m.)
Deposited	2 years, 1 month ago (July 24, 2023, 12:19 a.m.)
Indexed	1 week, 6 days ago (Aug. 12, 2025, 6:13 p.m.)
Issued	51 years, 9 months ago (Nov. 1, 1973)
Published	51 years, 9 months ago (Nov. 1, 1973)
Published Online	51 years, 9 months ago (Nov. 1, 1973)
Published Print	51 years, 9 months ago (Nov. 1, 1973)

Funders 0

None

BibTeX

@article{Tilney_1973, title={MICROTUBULES: EVIDENCE FOR 13 PROTOFILAMENTS}, volume={59}, ISSN={0021-9525}, url={http://dx.doi.org/10.1083/jcb.59.2.267}, DOI={10.1083/jcb.59.2.267}, number={2}, journal={The Journal of Cell Biology}, publisher={Rockefeller University Press}, author={Tilney, Lewis G. and Bryan, Joseph and Bush, Doris J. and Fujiwara, Keigi and Mooseker, Mark S. and Murphy, Douglas B. and Snyder, Daniel H.}, year={1973}, month=nov, pages={267–275} }

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