Abstract
We report the identification of a putative v-SNARE (GOS-28), localized primarily to transport vesicles at the terminal rims of Golgi stacks. In vitro, GOS-28, A Golgi SNARE of 28 kD, is efficiently packaged into Golgi-derived vesicles, which are most likely COPI coated. Antibodies directed against GOS-28 block its ability to bind alpha-SNAP, partially inhibit transport from the cis to the medial cisternae, and do not inhibit budding of COP-coated vesicles, but do accumulate docked uncoated vesicles.
Dates
Type | When |
---|---|
Created | 21 years, 3 months ago (May 14, 2004, 9:23 p.m.) |
Deposited | 2 years, 1 month ago (July 22, 2023, 2:20 a.m.) |
Indexed | 4 months, 2 weeks ago (April 16, 2025, 12:28 p.m.) |
Issued | 29 years, 3 months ago (May 1, 1996) |
Published | 29 years, 3 months ago (May 1, 1996) |
Published Online | 29 years, 3 months ago (May 1, 1996) |
Published Print | 29 years, 3 months ago (May 1, 1996) |
@article{Nagahama_1996, title={A v-SNARE implicated in intra-Golgi transport.}, volume={133}, ISSN={1540-8140}, url={http://dx.doi.org/10.1083/jcb.133.3.507}, DOI={10.1083/jcb.133.3.507}, number={3}, journal={The Journal of cell biology}, publisher={Rockefeller University Press}, author={Nagahama, M and Orci, L and Ravazzola, M and Amherdt, M and Lacomis, L and Tempst, P and Rothman, J E and Söllner, T H}, year={1996}, month=may, pages={507–516} }