DOI: 10.1083/jcb.131.6.1517. The Chlamydomonas kinesin-like protein FLA10 is involved in motility associated with the flagellar membrane.

The Chlamydomonas kinesin-like protein FLA10 is involved in motility associated with the flagellar membrane.

10.1083/jcb.131.6.1517

Crossref journal-article

Rockefeller University Press

The Journal of cell biology (291)

Abstract

The Chlamydomonas FLA10 gene was shown to encode a flagellar kinesin-like protein (Walther, Z., M. Vashishtha, and J.L. Hall. 1994. J. Cell Biol. 126:175-188). By using a temperature-sensitive allele of FLA10, we have determined that the FLA10 protein is necessary for both the bidirectional movement of polystyrene beads on the flagellar membrane and intraflagellar transport (IFT), the bidirectional movement of granule-like particles beneath the flagellar membrane (Kozminski, K.G., K.A. Johnson, P. Forscher, and J.L. Rosenbaum. 1993. Proc. Natl. Acad. Sci. (USA). 90:5519-5523). In addition, we have correlated the presence and position of the IFT particles visualized by light microscopy with that of the electron dense complexes (rafts) observed beneath the flagellar membrane by electron microscopy. A role for FLA10 in submembranous or flagellar surface motility is also strongly supported by the immunolocalization of FLA10 to the region between the axonemal outer doublet microtubules and the flagellar membrane.

Bibliography

Kozminski, K. G., Beech, P. L., & Rosenbaum, J. L. (1995). The Chlamydomonas kinesin-like protein FLA10 is involved in motility associated with the flagellar membrane. The Journal of Cell Biology, 131(6), 1517â1527.

Authors 3

K G Kozminski (first)
P L Beech (additional)
J L Rosenbaum (additional)

References 0 Referenced 530

None

Dates

Type	When
Created	21 years, 3 months ago (May 14, 2004, 9:23 p.m.)
Deposited	2 years, 1 month ago (July 22, 2023, 2:11 a.m.)
Indexed	1 week, 1 day ago (Aug. 23, 2025, 9:47 p.m.)
Issued	29 years, 8 months ago (Dec. 15, 1995)
Published	29 years, 8 months ago (Dec. 15, 1995)
Published Online	29 years, 8 months ago (Dec. 15, 1995)
Published Print	29 years, 8 months ago (Dec. 15, 1995)

Funders 0

None

BibTeX

@article{Kozminski_1995, title={The Chlamydomonas kinesin-like protein FLA10 is involved in motility associated with the flagellar membrane.}, volume={131}, ISSN={1540-8140}, url={http://dx.doi.org/10.1083/jcb.131.6.1517}, DOI={10.1083/jcb.131.6.1517}, number={6}, journal={The Journal of cell biology}, publisher={Rockefeller University Press}, author={Kozminski, K G and Beech, P L and Rosenbaum, J L}, year={1995}, month=dec, pages={1517–1527} }

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