DOI: 10.1083/jcb.115.1.31. Rab1b regulates vesicular transport between the endoplasmic reticulum and successive Golgi compartments.

Rab1b regulates vesicular transport between the endoplasmic reticulum and successive Golgi compartments.

10.1083/jcb.115.1.31

Crossref journal-article

Rockefeller University Press

The Journal of cell biology (291)

Abstract

We report an essential role for the ras-related small GTP-binding protein rab1b in vesicular transport in mammalian cells. mAbs detect rab1b in both the ER and Golgi compartments. Using an assay which reconstitutes transport between the ER and the cis-Golgi compartment, we find that rab1b is required during an initial step in export of protein from the ER. In addition, it is also required for transport of protein between successive cis- and medial-Golgi compartments. We suggest that rab1b may provide a common link between upstream and downstream components of the vesicular fission and fusion machinery functioning in early compartments of the secretory pathway.

Bibliography

Plutner, H., Cox, A. D., Pind, S., Khosravi-Far, R., Bourne, J. R., Schwaninger, R., Der, C. J., & Balch, W. E. (1991). Rab1b regulates vesicular transport between the endoplasmic reticulum and successive Golgi compartments. The Journal of Cell Biology, 115(1), 31â43.

Authors 8

H Plutner (first)
A D Cox (additional)
S Pind (additional)
R Khosravi-Far (additional)
J R Bourne (additional)
R Schwaninger (additional)
C J Der (additional)
W E Balch (additional)

References 0 Referenced 318

None

Dates

Type	When
Created	21 years, 3 months ago (May 14, 2004, 8:18 p.m.)
Deposited	2 years, 1 month ago (July 21, 2023, 9:34 p.m.)
Indexed	2 hours, 33 minutes ago (Aug. 22, 2025, 12:46 a.m.)
Issued	33 years, 10 months ago (Oct. 1, 1991)
Published	33 years, 10 months ago (Oct. 1, 1991)
Published Online	33 years, 10 months ago (Oct. 1, 1991)
Published Print	33 years, 10 months ago (Oct. 1, 1991)

Funders 0

None

BibTeX

@article{Plutner_1991, title={Rab1b regulates vesicular transport between the endoplasmic reticulum and successive Golgi compartments.}, volume={115}, ISSN={1540-8140}, url={http://dx.doi.org/10.1083/jcb.115.1.31}, DOI={10.1083/jcb.115.1.31}, number={1}, journal={The Journal of cell biology}, publisher={Rockefeller University Press}, author={Plutner, H and Cox, A D and Pind, S and Khosravi-Far, R and Bourne, J R and Schwaninger, R and Der, C J and Balch, W E}, year={1991}, month=oct, pages={31–43} }

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