DOI: 10.1083/jcb.111.6.2353. Import of ADP/ATP carrier into mitochondria: two receptors act in parallel.

Import of ADP/ATP carrier into mitochondria: two receptors act in parallel.

10.1083/jcb.111.6.2353

Crossref journal-article

Rockefeller University Press

The Journal of cell biology (291)

Abstract

We have identified the yeast homologue of Neurospora crassa MOM72, the mitochondrial import receptor for the ADP/ATP carrier (AAC), by functional studies and by cDNA sequencing. Mitochondria of a yeast mutant in which the gene for MOM72 was disrupted were impaired in specific binding and import of AAC. Unexpectedly, we found a residual, yet significant import of AAC into mitochondria lacking MOM72 that occurred via the receptor MOM19. We conclude that both MOM72 and MOM19 can direct AAC into mitochondria, albeit with different efficiency. Moreover, the precursor of MOM72 apparently does not require a positively charged sequence at the extreme amino terminus for targeting to mitochondria.

Bibliography

Steger, H. F., SÃ¶llner, T., Kiebler, M., Dietmeier, K. A., Pfaller, R., TrÃ¼lzsch, K. S., Tropschug, M., Neupert, W., & Pfanner, N. (1990). Import of ADP/ATP carrier into mitochondria: two receptors act in parallel. The Journal of Cell Biology, 111(6), 2353â2363.

Authors 9

H F Steger (first)
T Söllner (additional)
M Kiebler (additional)
K A Dietmeier (additional)
R Pfaller (additional)
K S Trülzsch (additional)
M Tropschug (additional)
W Neupert (additional)
N Pfanner (additional)

References 0 Referenced 165

None

Dates

Type	When
Created	21 years, 3 months ago (May 14, 2004, 8:18 p.m.)
Deposited	2 years, 1 month ago (July 21, 2023, 9:49 p.m.)
Indexed	2 months ago (June 27, 2025, 6:35 a.m.)
Issued	34 years, 9 months ago (Dec. 1, 1990)
Published	34 years, 9 months ago (Dec. 1, 1990)
Published Online	34 years, 9 months ago (Dec. 1, 1990)
Published Print	34 years, 9 months ago (Dec. 1, 1990)

Funders 0

None

BibTeX

@article{Steger_1990, title={Import of ADP/ATP carrier into mitochondria: two receptors act in parallel.}, volume={111}, ISSN={1540-8140}, url={http://dx.doi.org/10.1083/jcb.111.6.2353}, DOI={10.1083/jcb.111.6.2353}, number={6}, journal={The Journal of cell biology}, publisher={Rockefeller University Press}, author={Steger, H F and Söllner, T and Kiebler, M and Dietmeier, K A and Pfaller, R and Trülzsch, K S and Tropschug, M and Neupert, W and Pfanner, N}, year={1990}, month=dec, pages={2353–2363} }

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