DOI: 10.1083/jcb.111.6.2275. Cell-specific accumulation of Drosophila proteasomes (MCP) during early development.

Cell-specific accumulation of Drosophila proteasomes (MCP) during early development.

10.1083/jcb.111.6.2275

Crossref journal-article

Rockefeller University Press

The Journal of cell biology (291)

Abstract

The proteasome (MCP) is a high relative molecular mass multicatalytic proteinase complex composed of nonidentical protein subunits. We have investigated the cellular distribution of the enzyme complex during Drosophila embryogenesis using the proteasome specific antibodies N19-35 and N19-28 for immunocytology. Antibody staining of whole-mount embryos shows that during embryogenesis proteasomes are present in proliferating cells and that their accumulation and turnover is differentially regulated. Our data suggest that the proteasome may serve different proteolytic processes and that the enzyme may be involved in cell-specific proteolytic events required for cell proliferation and morphogenesis during early Drosophila development.

Bibliography

Klein, U., Gernold, M., & Kloetzel, P. M. (1990). Cell-specific accumulation of Drosophila proteasomes (MCP) during early development. The Journal of Cell Biology, 111(6), 2275â2282.

Authors 3

U Klein (first)
M Gernold (additional)
P M Kloetzel (additional)

References 0 Referenced 53

None

Dates

Type	When
Created	21 years, 3 months ago (May 14, 2004, 8:18 p.m.)
Deposited	2 years, 1 month ago (July 21, 2023, 9:15 p.m.)
Indexed	1 month, 3 weeks ago (July 11, 2025, 6:42 a.m.)
Issued	34 years, 9 months ago (Dec. 1, 1990)
Published	34 years, 9 months ago (Dec. 1, 1990)
Published Online	34 years, 9 months ago (Dec. 1, 1990)
Published Print	34 years, 9 months ago (Dec. 1, 1990)

Funders 0

None

BibTeX

@article{Klein_1990, title={Cell-specific accumulation of Drosophila proteasomes (MCP) during early development.}, volume={111}, ISSN={1540-8140}, url={http://dx.doi.org/10.1083/jcb.111.6.2275}, DOI={10.1083/jcb.111.6.2275}, number={6}, journal={The Journal of cell biology}, publisher={Rockefeller University Press}, author={Klein, U and Gernold, M and Kloetzel, P M}, year={1990}, month=dec, pages={2275–2282} }

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