DOI: 10.1083/jcb.108.6.2083. Primary structure analysis of an integral membrane glycoprotein of the nuclear pore.

Primary structure analysis of an integral membrane glycoprotein of the nuclear pore.

10.1083/jcb.108.6.2083

Crossref journal-article

Rockefeller University Press

The Journal of cell biology (291)

Abstract

The complete primary structure of an integral membrane glycoprotein of the nuclear pore was deduced from the cDNA sequence. The cDNA encodes a polypeptide of 204,205 D containing a 25-residue-long signal sequence, two hydrophobic segments that could function as transmembrane segments, and 13 potential N-linked oligosaccharide addition sites. Endoglycosidase H reduces the molecular mass by approximately 9 kD suggesting that not all of these 13 sites are used. We discuss possible models for the topology of this protein in the pore membrane as well as a possible role in the formation of pores and pore complexes.

Bibliography

Wozniak, R. W., Bartnik, E., & Blobel, G. (1989). Primary structure analysis of an integral membrane glycoprotein of the nuclear pore. The Journal of Cell Biology, 108(6), 2083â2092.

Authors 3

R W Wozniak (first)
E Bartnik (additional)
G Blobel (additional)

References 0 Referenced 161

None

Dates

Type	When
Created	21 years, 3 months ago (May 14, 2004, 8:18 p.m.)
Deposited	2 years, 1 month ago (July 21, 2023, 9:42 p.m.)
Indexed	2 weeks, 3 days ago (Aug. 5, 2025, 8:56 a.m.)
Issued	36 years, 2 months ago (June 1, 1989)
Published	36 years, 2 months ago (June 1, 1989)
Published Online	36 years, 2 months ago (June 1, 1989)
Published Print	36 years, 2 months ago (June 1, 1989)

Funders 0

None

BibTeX

@article{Wozniak_1989, title={Primary structure analysis of an integral membrane glycoprotein of the nuclear pore.}, volume={108}, ISSN={1540-8140}, url={http://dx.doi.org/10.1083/jcb.108.6.2083}, DOI={10.1083/jcb.108.6.2083}, number={6}, journal={The Journal of cell biology}, publisher={Rockefeller University Press}, author={Wozniak, R W and Bartnik, E and Blobel, G}, year={1989}, month=jun, pages={2083–2092} }

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