DOI: 10.1083/jcb.105.3.1099. Lamins A and C appear during retinoic acid-induced differentiation of mouse embryonal carcinoma cells.

Lamins A and C appear during retinoic acid-induced differentiation of mouse embryonal carcinoma cells.

10.1083/jcb.105.3.1099

Crossref journal-article

Rockefeller University Press

The Journal of cell biology (291)

Abstract

The lamin complement of nuclear matrix isolated from F9 embryonal carcinoma cells was studied during retinoic acid-induced differentiation in culture. Differentiation of the original cells into parietal endoderm-like cells was accompanied by the gradual appearance of lamins A and C while lamin B was present throughout all stages. Lamins were identified by their molecular masses, isoelectric points, recognition by a monoclonal antibody and a polyclonal antiserum, and by peptide mapping. The increase in the amounts of lamins A and C found in the matrix was due to de novo synthesis as no extranuclear pools of these lamins were detected in the undifferentiated cells. These results provide biochemical evidence that, as in amphibian embryogenesis, there are variations in nuclear lamina composition during mammalian development.

Bibliography

Lebel, S., Lampron, C., Royal, A., & Raymond, Y. (1987). Lamins A and C appear during retinoic acid-induced differentiation of mouse embryonal carcinoma cells. The Journal of Cell Biology, 105(3), 1099â1104.

Authors 4

S Lebel (first)
C Lampron (additional)
A Royal (additional)
Y Raymond (additional)

References 0 Referenced 86

None

Dates

Type	When
Created	21 years, 3 months ago (May 14, 2004, 8:18 p.m.)
Deposited	2 years, 1 month ago (July 21, 2023, 8:20 p.m.)
Indexed	1 month, 2 weeks ago (July 12, 2025, 6:48 p.m.)
Issued	37 years, 11 months ago (Sept. 1, 1987)
Published	37 years, 11 months ago (Sept. 1, 1987)
Published Online	37 years, 11 months ago (Sept. 1, 1987)
Published Print	37 years, 11 months ago (Sept. 1, 1987)

Funders 0

None

BibTeX

@article{Lebel_1987, title={Lamins A and C appear during retinoic acid-induced differentiation of mouse embryonal carcinoma cells.}, volume={105}, ISSN={1540-8140}, url={http://dx.doi.org/10.1083/jcb.105.3.1099}, DOI={10.1083/jcb.105.3.1099}, number={3}, journal={The Journal of cell biology}, publisher={Rockefeller University Press}, author={Lebel, S and Lampron, C and Royal, A and Raymond, Y}, year={1987}, month=sep, pages={1099–1104} }

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