Abstract
Adult mouse brain contains at least two distinct spectrin subtypes, both consisting of 240-kD and 235-kD subunits. Brain spectrin(240/235) is found in neuronal axons, but not dendrites, when immunohistochemistry is performed with antibody raised against brain spectrin isolated from enriched synaptic/axonal membranes. A second spectrin subtype, brain spectrin(240/235E), is exclusively recognized by red blood cell spectrin antibody. Brain spectrin(240/235E) is confined to neuronal cell bodies and dendrites, and some glial cells, but is not present in axons or presynaptic terminals.
Dates
Type | When |
---|---|
Created | 21 years, 3 months ago (May 14, 2004, 8:18 p.m.) |
Deposited | 2 years, 1 month ago (July 21, 2023, 7:58 p.m.) |
Indexed | 1 year ago (Aug. 6, 2024, 2:01 a.m.) |
Issued | 39 years, 3 months ago (June 1, 1986) |
Published | 39 years, 3 months ago (June 1, 1986) |
Published Online | 39 years, 3 months ago (June 1, 1986) |
Published Print | 39 years, 3 months ago (June 1, 1986) |
@article{Riederer_1986, title={Brain spectrin(240/235) and brain spectrin(240/235E): two distinct spectrin subtypes with different locations within mammalian neural cells.}, volume={102}, ISSN={1540-8140}, url={http://dx.doi.org/10.1083/jcb.102.6.2088}, DOI={10.1083/jcb.102.6.2088}, number={6}, journal={The Journal of cell biology}, publisher={Rockefeller University Press}, author={Riederer, B M and Zagon, I S and Goodman, S R}, year={1986}, month=jun, pages={2088–2097} }