Abstract
Cytoplasmic extracts of meiotically mature mouse oocytes were injected into immature Xenopus laevis oocytes, which underwent germinal vesicle breakdown within 2 h. Germinal vesicle breakdown was not inhibited by incubation of the Xenopus oocytes in cycloheximide (20 micrograms/ml). Identically prepared extracts of meiotically immature mouse oocytes, arrested at the germinal vesicle stage by dibutyryl cyclic AMP (100 micrograms/ml), did not induce germinal vesicle breakdown in Xenopus oocytes. The results show that maturation-promoting factor activity appears during the course of oocyte maturation in the mouse.
Dates
Type | When |
---|---|
Created | 21 years, 3 months ago (May 14, 2004, 8:18 p.m.) |
Deposited | 2 years, 1 month ago (July 21, 2023, 7:14 p.m.) |
Indexed | 2 months, 3 weeks ago (June 5, 2025, 7:27 a.m.) |
Issued | 40 years, 3 months ago (May 1, 1985) |
Published | 40 years, 3 months ago (May 1, 1985) |
Published Online | 40 years, 3 months ago (May 1, 1985) |
Published Print | 40 years, 3 months ago (May 1, 1985) |
@article{Sorensen_1985, title={Active maturation-promoting factor is present in mature mouse oocytes.}, volume={100}, ISSN={1540-8140}, url={http://dx.doi.org/10.1083/jcb.100.5.1637}, DOI={10.1083/jcb.100.5.1637}, number={5}, journal={The Journal of cell biology}, publisher={Rockefeller University Press}, author={Sorensen, R A and Cyert, M S and Pedersen, R A}, year={1985}, month=may, pages={1637–1640} }