DOI: 10.1080/1475636042000196222. CYP 17 and CYP 19 Inhibitors. Evaluation of Fluorine Effects on the Inhibiting Activity of Regioselectively Fluorinated 1-(Naphthalen-2-ylmethyl)imidazoles

CYP 17 and CYP 19 Inhibitors. Evaluation of Fluorine Effects on the Inhibiting Activity of Regioselectively Fluorinated 1-(Naphthalen-2-ylmethyl)imidazoles

10.1080/1475636042000196222

Crossref journal-article

Informa UK Limited

Journal of Enzyme Inhibition and Medicinal Chemistry (301)

Bibliography

Hartmann, R. W., Palusczak, A., Lacan, F., Ricci, G., & Ruzziconi, R. (2004). CYP 17 and CYP 19 Inhibitors. Evaluation of Fluorine Effects on the Inhibiting Activity of Regioselectively Fluorinated 1-(Naphthalen-2-ylmethyl)imidazoles. Journal of Enzyme Inhibition and Medicinal Chemistry, 19(2), 145â155.

Authors 5

Rolf W. Hartmann (first)
Anja Palusczak (additional)
Fabrice Lacan (additional)
Giacomo Ricci (additional)
Renzo Ruzziconi (additional)

References 14 Referenced 18

10.1021/jm970337k / Med. Chem. by Ling Y.-Z. (1997)
10.1021/jm970568r / Med. Chem. by Njar V.C.O. (1998)
10.1016/S0968-0896(99)00160-1 / Med. Chem. by Wachall B.G. (1999)
{'key': 'CIT0004', 'volume-title': 'Arch. Pharm. Pharm. Med. Chem', 'author': 'Hartmann R.W.', 'year': '1996'} / Arch. Pharm. Pharm. Med. Chem by Hartmann R.W. (1996)
10.1021/jm991180u / Med. Chem. by Jacobs C. (2000)
Schlosser, M. (1999) “The Chemical and Physiological Size of Fluorine”, In: Soloshonok, V.A., eds,Enantiocontrolled Syn- thesis of Fluoro-Organic Compounds: Stereochemical Challenges and Biomedical Targets(John Wiley & Sons Ltd, Chichester).
See for example inStudies in Organic Chemistry 48Filler, R., Kobayashi, Y., Yagupolskii, L.M., eds, (1993) “Organofluorine Compounds in Medicinal Chemistry and Biomedical Appli- cations”, (Elsevier).
{'issue': '2', 'key': 'CIT0008', 'volume': '66', 'author': 'Gourve`s J.-P.', 'year': '2001', 'journal-title': 'Org. Chem.'} / Org. Chem. by Gourve`s J.-P. (2001)
{'issue': '5', 'key': 'CIT0009', 'first-page': 'C7', 'volume': '502', 'author': 'Reetz M.T.', 'year': '1995', 'journal-title': 'Organomet. Chem.'} / Organomet. Chem. by Reetz M.T. (1995)
{'key': 'CIT0010', 'volume-title': 'Synlett', 'author': 'Baciocchi E.', 'year': '1990'} / Synlett by Baciocchi E. (1990)
Baciocchi, E., Civitarese, G. and Ruzziconi, R. (1987)Tetrahedron Lett. 28, 5357, Diethyl (2,2-dimetoxyethyl)- malonate (DMEM) was conveniently prepared in 75% yield by CAN-promoted oxidative addition of dimethyl malonate to vinyl acetate in methanol at room tempera- ture. This procedure, leading to the mono-acetal exclusively, is certainly preferable to that involving bromine replacement ofa-bromoacetaldehyde diethyl acetal by sodium dimethyl malonate which leads inevitably to a mixture of mono- and dialkylmalonate with consequent separation nuisance.
10.1016/S0021-9258(20)79735-8 / Biol. Chem. by Thompson E.A. (1974)
10.1021/jm00158a007 / Med. Chem. by Hartmann R.W. (1986)
10.3109/14756369409020194 / Enz. Inhib. by Sergejew T. (1994)

Dates

Type	When
Created	21 years, 3 months ago (May 13, 2004, 1:59 p.m.)
Deposited	4 years, 2 months ago (June 17, 2021, 11:07 a.m.)
Indexed	1 year, 6 months ago (Feb. 23, 2024, 1:24 p.m.)
Issued	21 years, 5 months ago (April 1, 2004)
Published	21 years, 5 months ago (April 1, 2004)
Published Online	16 years, 11 months ago (Oct. 3, 2008)
Published Print	21 years, 5 months ago (April 1, 2004)

Funders 0

None

BibTeX

@article{Hartmann_2004, title={CYP 17 and CYP 19 Inhibitors. Evaluation of Fluorine Effects on the Inhibiting Activity of Regioselectively Fluorinated 1-(Naphthalen-2-ylmethyl)imidazoles}, volume={19}, ISSN={1475-6374}, url={http://dx.doi.org/10.1080/1475636042000196222}, DOI={10.1080/1475636042000196222}, number={2}, journal={Journal of Enzyme Inhibition and Medicinal Chemistry}, publisher={Informa UK Limited}, author={Hartmann, Rolf W. and Palusczak, Anja and Lacan, Fabrice and Ricci, Giacomo and Ruzziconi, Renzo}, year={2004}, month=apr, pages={145–155} }

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