DOI: 10.1074/jbc.m700548200. IRAK-4 Kinase Activity Is Required for Interleukin-1 (IL-1) Receptor- and Toll-like Receptor 7-mediated Signaling and Gene Expression

IRAK-4 Kinase Activity Is Required for Interleukin-1 (IL-1) Receptor- and Toll-like Receptor 7-mediated Signaling and Gene Expression

10.1074/jbc.m700548200

Crossref journal-article

Elsevier BV

Journal of Biological Chemistry (78)

Bibliography

Koziczak-Holbro, M., Joyce, C., GlÃ¼ck, A., Kinzel, B., MÃ¼ller, M., Tschopp, C., Mathison, J. C., Davis, C. N., & Gram, H. (2007). IRAK-4 Kinase Activity Is Required for Interleukin-1 (IL-1) Receptor- and Toll-like Receptor 7-mediated Signaling and Gene Expression. Journal of Biological Chemistry, 282(18), 13552â13560.

Authors 9

Magdalena Koziczak-Holbro (first)
Claire Joyce (additional)
Anton Glück (additional)
Bernd Kinzel (additional)
Matthias Müller (additional)
Claude Tschopp (additional)
John C. Mathison (additional)
Christopher N. Davis (additional)
Hermann Gram (additional)

References 33 Referenced 72

10.1093/intimm/dxh186 / Int. Immunol. by Takeda (2005)
10.1016/S1359-6101(00)00006-X / Cytokine Growth Factor Rev. by Means (2000)
10.1016/S0167-4889(02)00320-8 / Biochim. Biophys. Acta by Martin (2002)
10.1016/S1097-2765(03)00053-4 / Mol. Cell by Janssens (2003)
10.1073/pnas.082100399 / Proc. Natl. Acad. Sci. U. S. A. by Li (2002)
10.1074/jbc.M309251200 / J. Biol. Chem. by Kollewe (2004)
10.1074/jbc.272.34.21540 / J. Biol. Chem. by Yamin (1997)
10.1128/MCB.22.20.7158-7167.2002 / Mol. Cell. Biol. by Jiang (2002)
10.1038/35085597 / Nature by Wang (2001)
10.1172/JCI11830 / J. Clin. Investig. by Tak (2001)
10.1006/excr.1999.4685 / Exp. Cell Res. by Wisdom (1999)
10.1016/j.smim.2003.10.003 / Semin. Immunol. by Takeda (2004)
10.1016/S1471-4906(02)02298-6 / Trends Immunol. by Suzuki (2002)
10.1038/nature736 / Nature by Suzuki (2002)
10.4049/jimmunol.174.11.6587 / J. Immunol. by Medvedev (2005)
10.1126/science.1081902 / Science by Picard (2003)
10.1074/jbc.M402666200 / J. Biol. Chem. by Lye (2004)
10.1074/jbc.M400785200 / J. Biol. Chem. by Qin (2004)
10.1016/S0014-5793(99)00322-1 / FEBS Lett. by Knop (1999)
10.1042/bj3390227 / Biochem. J. by Maschera (1999)
10.1152/ajpcell.00228.2003 / Am. J. Physiol. by Comalada (2003)
10.1111/j.1471-4159.2006.03951.x / J. Neurochem. by Davis (2006)
10.1128/MCB.20.9.3210-3223.2000 / Mol. Cell. Biol. by Lane (2000)
10.1021/bi00060a005 / Biochemistry by Zheng (1993)
{'key': '10.1074/jbc.M700548200_bib25', 'first-page': '2327', 'volume': '10', 'author': 'Libermann', 'year': '1990', 'journal-title': 'Mol. Cell. Biol.'} / Mol. Cell. Biol. by Libermann (1990)
10.1016/j.immuni.2006.09.009 / Immunity by Minegishi (2006)
10.1084/jem.20021790 / J. Exp. Med. by Burns (2003)
10.1016/j.str.2006.11.001 / Structure (Lond.) by Wang (2006)
10.1016/j.bbrc.2006.11.068 / Biochem. Biophys. Res. Commun. by Cheng (2007)
10.1038/ni1014 / Nat. Immunol. by Huang (2004)
10.1038/nature04768 / Nature by Gilchrist (2006)
10.1128/MCB.19.6.4311 / Mol. Cell. Biol. by Lai (1999)
10.1126/science.1124256 / Science by Suzuki (2006)

Dates

Type	When
Created	18 years, 6 months ago (March 2, 2007, 8:52 p.m.)
Deposited	3 years, 8 months ago (Dec. 31, 2021, 9:29 a.m.)
Indexed	3 weeks, 4 days ago (Aug. 12, 2025, 5:32 p.m.)
Issued	18 years, 4 months ago (May 1, 2007)
Published	18 years, 4 months ago (May 1, 2007)
Published Print	18 years, 4 months ago (May 1, 2007)

Funders 0

None

BibTeX

@article{Koziczak_Holbro_2007, title={IRAK-4 Kinase Activity Is Required for Interleukin-1 (IL-1) Receptor- and Toll-like Receptor 7-mediated Signaling and Gene Expression}, volume={282}, ISSN={0021-9258}, url={http://dx.doi.org/10.1074/jbc.m700548200}, DOI={10.1074/jbc.m700548200}, number={18}, journal={Journal of Biological Chemistry}, publisher={Elsevier BV}, author={Koziczak-Holbro, Magdalena and Joyce, Claire and Glück, Anton and Kinzel, Bernd and Müller, Matthias and Tschopp, Claude and Mathison, John C. and Davis, Christopher N. and Gram, Hermann}, year={2007}, month=may, pages={13552–13560} }

JSON

{
  "indexed": {
    "date-parts": [
      [
        2025,
        8,
        12
      ]
    ],
    "date-time": "2025-08-12T21:32:24Z",
    "timestamp": 1755034344962
  },
  "reference-count": 33,
  "publisher": "Elsevier BV",
  "issue": "18",
  "license": [
    {
      "start": {
        "date-parts": [
          [
            2007,
            5,
            1
          ]
        ],
        "date-time": "2007-05-01T00:00:00Z",
        "timestamp": 1177977600000
      },
      "content-version": "tdm",
      "delay-in-days": 0,
      "URL": "https://www.elsevier.com/tdm/userlicense/1.0/"
    },
    {
      "start": {
        "date-parts": [
          [
            2020,
            10,
            31
          ]
        ],
        "date-time": "2020-10-31T00:00:00Z",
        "timestamp": 1604102400000
      },
      "content-version": "vor",
      "delay-in-days": 4932,
      "URL": "http://creativecommons.org/licenses/by/4.0/"
    }
  ],
  "content-domain": {
    "domain": [],
    "crossmark-restriction": false
  },
  "published-print": {
    "date-parts": [
      [
        2007,
        5
      ]
    ]
  },
  "DOI": "10.1074/jbc.m700548200",
  "type": "journal-article",
  "created": {
    "date-parts": [
      [
        2007,
        3,
        3
      ]
    ],
    "date-time": "2007-03-03T01:52:04Z",
    "timestamp": 1172886724000
  },
  "page": "13552-13560",
  "source": "Crossref",
  "is-referenced-by-count": 72,
  "title": "IRAK-4 Kinase Activity Is Required for Interleukin-1 (IL-1) Receptor- and Toll-like Receptor 7-mediated Signaling and Gene Expression",
  "prefix": "10.1016",
  "volume": "282",
  "author": [
    {
      "given": "Magdalena",
      "family": "Koziczak-Holbro",
      "sequence": "first",
      "affiliation": []
    },
    {
      "given": "Claire",
      "family": "Joyce",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "Anton",
      "family": "Gl\u00fcck",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "Bernd",
      "family": "Kinzel",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "Matthias",
      "family": "M\u00fcller",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "Claude",
      "family": "Tschopp",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "John C.",
      "family": "Mathison",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "Christopher N.",
      "family": "Davis",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "Hermann",
      "family": "Gram",
      "sequence": "additional",
      "affiliation": []
    }
  ],
  "member": "78",
  "reference": [
    {
      "key": "10.1074/jbc.M700548200_bib1",
      "doi-asserted-by": "crossref",
      "first-page": "1",
      "DOI": "10.1093/intimm/dxh186",
      "volume": "17",
      "author": "Takeda",
      "year": "2005",
      "journal-title": "Int. Immunol."
    },
    {
      "key": "10.1074/jbc.M700548200_bib2",
      "doi-asserted-by": "crossref",
      "first-page": "219",
      "DOI": "10.1016/S1359-6101(00)00006-X",
      "volume": "11",
      "author": "Means",
      "year": "2000",
      "journal-title": "Cytokine Growth Factor Rev."
    },
    {
      "key": "10.1074/jbc.M700548200_bib3",
      "doi-asserted-by": "crossref",
      "first-page": "265",
      "DOI": "10.1016/S0167-4889(02)00320-8",
      "volume": "1592",
      "author": "Martin",
      "year": "2002",
      "journal-title": "Biochim. Biophys. Acta"
    },
    {
      "key": "10.1074/jbc.M700548200_bib4",
      "doi-asserted-by": "crossref",
      "first-page": "293",
      "DOI": "10.1016/S1097-2765(03)00053-4",
      "volume": "11",
      "author": "Janssens",
      "year": "2003",
      "journal-title": "Mol. Cell"
    },
    {
      "key": "10.1074/jbc.M700548200_bib5",
      "doi-asserted-by": "crossref",
      "first-page": "5567",
      "DOI": "10.1073/pnas.082100399",
      "volume": "99",
      "author": "Li",
      "year": "2002",
      "journal-title": "Proc. Natl. Acad. Sci. U. S. A."
    },
    {
      "key": "10.1074/jbc.M700548200_bib6",
      "doi-asserted-by": "crossref",
      "first-page": "5227",
      "DOI": "10.1074/jbc.M309251200",
      "volume": "279",
      "author": "Kollewe",
      "year": "2004",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "10.1074/jbc.M700548200_bib7",
      "doi-asserted-by": "crossref",
      "first-page": "21540",
      "DOI": "10.1074/jbc.272.34.21540",
      "volume": "272",
      "author": "Yamin",
      "year": "1997",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "10.1074/jbc.M700548200_bib8",
      "doi-asserted-by": "crossref",
      "first-page": "7158",
      "DOI": "10.1128/MCB.22.20.7158-7167.2002",
      "volume": "22",
      "author": "Jiang",
      "year": "2002",
      "journal-title": "Mol. Cell. Biol."
    },
    {
      "key": "10.1074/jbc.M700548200_bib9",
      "doi-asserted-by": "crossref",
      "first-page": "346",
      "DOI": "10.1038/35085597",
      "volume": "412",
      "author": "Wang",
      "year": "2001",
      "journal-title": "Nature"
    },
    {
      "key": "10.1074/jbc.M700548200_bib10",
      "doi-asserted-by": "crossref",
      "first-page": "7",
      "DOI": "10.1172/JCI11830",
      "volume": "107",
      "author": "Tak",
      "year": "2001",
      "journal-title": "J. Clin. Investig."
    },
    {
      "key": "10.1074/jbc.M700548200_bib11",
      "doi-asserted-by": "crossref",
      "first-page": "180",
      "DOI": "10.1006/excr.1999.4685",
      "volume": "253",
      "author": "Wisdom",
      "year": "1999",
      "journal-title": "Exp. Cell Res."
    },
    {
      "key": "10.1074/jbc.M700548200_bib12",
      "doi-asserted-by": "crossref",
      "first-page": "3",
      "DOI": "10.1016/j.smim.2003.10.003",
      "volume": "16",
      "author": "Takeda",
      "year": "2004",
      "journal-title": "Semin. Immunol."
    },
    {
      "key": "10.1074/jbc.M700548200_bib13",
      "doi-asserted-by": "crossref",
      "first-page": "503",
      "DOI": "10.1016/S1471-4906(02)02298-6",
      "volume": "23",
      "author": "Suzuki",
      "year": "2002",
      "journal-title": "Trends Immunol."
    },
    {
      "key": "10.1074/jbc.M700548200_bib14",
      "doi-asserted-by": "crossref",
      "first-page": "750",
      "DOI": "10.1038/nature736",
      "volume": "416",
      "author": "Suzuki",
      "year": "2002",
      "journal-title": "Nature"
    },
    {
      "key": "10.1074/jbc.M700548200_bib15",
      "doi-asserted-by": "crossref",
      "first-page": "6587",
      "DOI": "10.4049/jimmunol.174.11.6587",
      "volume": "174",
      "author": "Medvedev",
      "year": "2005",
      "journal-title": "J. Immunol."
    },
    {
      "key": "10.1074/jbc.M700548200_bib16",
      "doi-asserted-by": "crossref",
      "first-page": "2076",
      "DOI": "10.1126/science.1081902",
      "volume": "299",
      "author": "Picard",
      "year": "2003",
      "journal-title": "Science"
    },
    {
      "key": "10.1074/jbc.M700548200_bib17",
      "doi-asserted-by": "crossref",
      "first-page": "40653",
      "DOI": "10.1074/jbc.M402666200",
      "volume": "279",
      "author": "Lye",
      "year": "2004",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "10.1074/jbc.M700548200_bib18",
      "doi-asserted-by": "crossref",
      "first-page": "26748",
      "DOI": "10.1074/jbc.M400785200",
      "volume": "279",
      "author": "Qin",
      "year": "2004",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "10.1074/jbc.M700548200_bib19",
      "doi-asserted-by": "crossref",
      "first-page": "81",
      "DOI": "10.1016/S0014-5793(99)00322-1",
      "volume": "448",
      "author": "Knop",
      "year": "1999",
      "journal-title": "FEBS Lett."
    },
    {
      "key": "10.1074/jbc.M700548200_bib20",
      "doi-asserted-by": "crossref",
      "first-page": "227",
      "DOI": "10.1042/bj3390227",
      "volume": "339",
      "author": "Maschera",
      "year": "1999",
      "journal-title": "Biochem. J."
    },
    {
      "key": "10.1074/jbc.M700548200_bib21",
      "doi-asserted-by": "crossref",
      "first-page": "C1235",
      "DOI": "10.1152/ajpcell.00228.2003",
      "volume": "285",
      "author": "Comalada",
      "year": "2003",
      "journal-title": "Am. J. Physiol."
    },
    {
      "key": "10.1074/jbc.M700548200_bib22",
      "doi-asserted-by": "crossref",
      "first-page": "1379",
      "DOI": "10.1111/j.1471-4159.2006.03951.x",
      "volume": "98",
      "author": "Davis",
      "year": "2006",
      "journal-title": "J. Neurochem."
    },
    {
      "key": "10.1074/jbc.M700548200_bib23",
      "doi-asserted-by": "crossref",
      "first-page": "3210",
      "DOI": "10.1128/MCB.20.9.3210-3223.2000",
      "volume": "20",
      "author": "Lane",
      "year": "2000",
      "journal-title": "Mol. Cell. Biol."
    },
    {
      "key": "10.1074/jbc.M700548200_bib24",
      "doi-asserted-by": "crossref",
      "first-page": "2154",
      "DOI": "10.1021/bi00060a005",
      "volume": "32",
      "author": "Zheng",
      "year": "1993",
      "journal-title": "Biochemistry"
    },
    {
      "key": "10.1074/jbc.M700548200_bib25",
      "first-page": "2327",
      "volume": "10",
      "author": "Libermann",
      "year": "1990",
      "journal-title": "Mol. Cell. Biol."
    },
    {
      "key": "10.1074/jbc.M700548200_bib26",
      "doi-asserted-by": "crossref",
      "first-page": "745",
      "DOI": "10.1016/j.immuni.2006.09.009",
      "volume": "25",
      "author": "Minegishi",
      "year": "2006",
      "journal-title": "Immunity"
    },
    {
      "key": "10.1074/jbc.M700548200_bib27",
      "doi-asserted-by": "crossref",
      "first-page": "263",
      "DOI": "10.1084/jem.20021790",
      "volume": "197",
      "author": "Burns",
      "year": "2003",
      "journal-title": "J. Exp. Med."
    },
    {
      "key": "10.1074/jbc.M700548200_bib28",
      "doi-asserted-by": "crossref",
      "first-page": "1835",
      "DOI": "10.1016/j.str.2006.11.001",
      "volume": "14",
      "author": "Wang",
      "year": "2006",
      "journal-title": "Structure (Lond.)"
    },
    {
      "key": "10.1074/jbc.M700548200_bib29",
      "doi-asserted-by": "crossref",
      "first-page": "609",
      "DOI": "10.1016/j.bbrc.2006.11.068",
      "volume": "352",
      "author": "Cheng",
      "year": "2007",
      "journal-title": "Biochem. Biophys. Res. Commun."
    },
    {
      "key": "10.1074/jbc.M700548200_bib30",
      "doi-asserted-by": "crossref",
      "first-page": "98",
      "DOI": "10.1038/ni1014",
      "volume": "5",
      "author": "Huang",
      "year": "2004",
      "journal-title": "Nat. Immunol."
    },
    {
      "key": "10.1074/jbc.M700548200_bib31",
      "doi-asserted-by": "crossref",
      "first-page": "173",
      "DOI": "10.1038/nature04768",
      "volume": "441",
      "author": "Gilchrist",
      "year": "2006",
      "journal-title": "Nature"
    },
    {
      "key": "10.1074/jbc.M700548200_bib32",
      "doi-asserted-by": "crossref",
      "first-page": "4311",
      "DOI": "10.1128/MCB.19.6.4311",
      "volume": "19",
      "author": "Lai",
      "year": "1999",
      "journal-title": "Mol. Cell. Biol."
    },
    {
      "key": "10.1074/jbc.M700548200_bib33",
      "doi-asserted-by": "crossref",
      "first-page": "1927",
      "DOI": "10.1126/science.1124256",
      "volume": "311",
      "author": "Suzuki",
      "year": "2006",
      "journal-title": "Science"
    }
  ],
  "container-title": "Journal of Biological Chemistry",
  "original-title": [],
  "language": "en",
  "link": [
    {
      "URL": "https://api.elsevier.com/content/article/PII:S0021925817474321?httpAccept=text/xml",
      "content-type": "text/xml",
      "content-version": "vor",
      "intended-application": "text-mining"
    },
    {
      "URL": "https://api.elsevier.com/content/article/PII:S0021925817474321?httpAccept=text/plain",
      "content-type": "text/plain",
      "content-version": "vor",
      "intended-application": "text-mining"
    },
    {
      "URL": "https://syndication.highwire.org/content/doi/10.1074/jbc.M700548200",
      "content-type": "unspecified",
      "content-version": "vor",
      "intended-application": "similarity-checking"
    }
  ],
  "deposited": {
    "date-parts": [
      [
        2021,
        12,
        31
      ]
    ],
    "date-time": "2021-12-31T14:29:55Z",
    "timestamp": 1640960995000
  },
  "score": 1,
  "resource": {
    "primary": {
      "URL": "https://linkinghub.elsevier.com/retrieve/pii/S0021925817474321"
    }
  },
  "subtitle": [],
  "short-title": [],
  "issued": {
    "date-parts": [
      [
        2007,
        5
      ]
    ]
  },
  "references-count": 33,
  "journal-issue": {
    "issue": "18",
    "published-print": {
      "date-parts": [
        [
          2007,
          5
        ]
      ]
    }
  },
  "alternative-id": [
    "S0021925817474321"
  ],
  "URL": "http://dx.doi.org/10.1074/jbc.M700548200",
  "relation": {},
  "ISSN": [
    "0021-9258"
  ],
  "subject": [],
  "container-title-short": "Journal of Biological Chemistry",
  "published": {
    "date-parts": [
      [
        2007,
        5
      ]
    ]
  }
}