DOI: 10.1074/jbc.m410233200. Phosphorylation of p53 on Key Serines Is Dispensable for Transcriptional Activation and Apoptosis

Phosphorylation of p53 on Key Serines Is Dispensable for Transcriptional Activation and Apoptosis

10.1074/jbc.m410233200

Crossref journal-article

Elsevier BV

Journal of Biological Chemistry (78)

Bibliography

Thompson, T., Tovar, C., Yang, H., Carvajal, D., Vu, B. T., Xu, Q., Wahl, G. M., Heimbrook, D. C., & Vassilev, L. T. (2004). Phosphorylation of p53 on Key Serines Is Dispensable for Transcriptional Activation and Apoptosis. Journal of Biological Chemistry, 279(51), 53015â53022.

Authors 9

Thelma Thompson (first)
Christian Tovar (additional)
Hong Yang (additional)
Daisy Carvajal (additional)
Binh T. Vu (additional)
Qunli Xu (additional)
Geoffrey M. Wahl (additional)
David C. Heimbrook (additional)
Lyubomir T. Vassilev (additional)

References 43 Referenced 187

10.1016/S0092-8674(00)81871-1 / Cell by Levine (1997)
10.1038/35042675 / Nature by Vogelstein (2000)
10.1007/s000180050273 / Cell. Mol. Life Sci. by Freedman (1999)
10.1016/S1044-579X(02)00099-8 / Semin. Cancer Biol. by Michael (2003)
10.1016/S0955-0674(03)00003-6 / Curr. Opin. Cell Biol. by Brooks (2003)
10.1038/sj.emboj.7600145 / EMBO J. by Stommel (2004)
10.1046/j.1432-1327.2001.02225.x / Eur. J. Biochem. by Apella (2001)
10.1038/sj.onc.1203013 / Oncogene by Jimenez (1999)
10.1038/sj.neo.7900073 / Neoplasia by Ljungman (2000)
10.1101/gad.12.18.2831 / Genes Dev. by Sakaguchi (1998)
10.1042/bj3420133 / Biochem. J. by Craig (1999)
10.1016/S0022-2836(02)00852-5 / J. Mol. Biol. by Schon (2002)
10.1038/sj.onc.1202951 / Oncogene by Meek (1999)
10.1038/376088a0 / Nature by Wang (1995)
10.1074/jbc.271.46.29380 / J. Biol. Chem. by Hao (1996)
10.1021/bi970759w / Biochemistry by Sakaguchi (1997)
10.1074/jbc.273.49.33048 / J. Biol. Chem. by Lambert (1998)
10.1093/emboj/18.24.7002 / EMBO J. by Dumaz (1999)
10.1128/MCB.19.2.1202 / Mol. Cell. Biol. by Liu (1999)
10.1038/ncb714 / Nat. Cell Biol. by D'Orazi (2002)
10.1074/jbc.C200093200 / J. Biol. Chem. by Saito (2002)
10.1038/nature01116 / Nature by Zheng (2002)
10.1038/nature01120 / Nature by Zacchi (2002)
10.1128/MCB.19.3.1751 / Mol. Cell. Biol. by Ashcroft (1999)
10.1128/MCB.22.8.2441-2449.2002 / Mol. Cell. Biol. by Wu (2002)
10.1074/jbc.M306938200 / J. Biol. Chem. by Chao (2003)
10.1128/MCB.24.3.976-984.2004 / Mol. Cell. Biol. by Sluss (2004)
10.1126/science.1092472 / Science by Vassilev (2004)
10.1073/pnas.96.13.7382 / Proc. Natl. Acad. Sci. U. S. A. by Ahrendt (1999)
10.1016/0092-8674(93)90500-P / Cell by el-Deiry (1993)
10.1002/bies.950151008 / Bioessays by Picksley (1993)
10.1073/pnas.97.1.109 / Proc. Natl. Acad. Sci. U. S. A. by Tan (2000)
{'key': '10.1074/jbc.M410233200_bib33', 'first-page': '1023', 'volume': '2', 'author': 'Yang', 'year': '2003', 'journal-title': 'Mol. Cancer Ther.'} / Mol. Cancer Ther. by Yang (2003)
10.1016/0092-8674(94)90534-7 / Cell by Symonds (1994)
10.1007/s00109-001-0293-3 / J. Mol. Med. by Schmitt (2002)
10.1038/370220a0 / Nature by Caelles (1994)
{'issue': 'Suppl. 3', 'key': '10.1074/jbc.M410233200_bib37', 'first-page': '337', 'volume': '11', 'author': 'Haupt', 'year': '1997', 'journal-title': 'Leukemia'} / Leukemia by Haupt (1997)
{'key': '10.1074/jbc.M410233200_bib38', 'first-page': '323', 'volume': '85', 'author': 'Steensma', 'year': '2003', 'journal-title': 'Methods Mol. Med.'} / Methods Mol. Med. by Steensma (2003)
10.2174/0929867013373994 / Curr. Med. Chem. by Perego (2001)
10.1006/excr.2001.5314 / Exp. Cell Res. by Xirodimas (2001)
10.1074/jbc.M305135200 / J. Biol. Chem. by Saito (2003)
10.1038/sj.onc.1207575 / Oncogene by Jackson (2004)
10.1016/S1097-2765(03)00050-9 / Mol. Cell by Mihara (2003)

Dates

Type	When
Created	20 years, 10 months ago (Oct. 7, 2004, 8:12 p.m.)
Deposited	3 years, 7 months ago (Jan. 1, 2022, 10:29 p.m.)
Indexed	11 months, 2 weeks ago (Sept. 12, 2024, 4:34 p.m.)
Issued	20 years, 8 months ago (Dec. 1, 2004)
Published	20 years, 8 months ago (Dec. 1, 2004)
Published Print	20 years, 8 months ago (Dec. 1, 2004)

Funders 0

None

BibTeX

@article{Thompson_2004, title={Phosphorylation of p53 on Key Serines Is Dispensable for Transcriptional Activation and Apoptosis}, volume={279}, ISSN={0021-9258}, url={http://dx.doi.org/10.1074/jbc.m410233200}, DOI={10.1074/jbc.m410233200}, number={51}, journal={Journal of Biological Chemistry}, publisher={Elsevier BV}, author={Thompson, Thelma and Tovar, Christian and Yang, Hong and Carvajal, Daisy and Vu, Binh T. and Xu, Qunli and Wahl, Geoffrey M. and Heimbrook, David C. and Vassilev, Lyubomir T.}, year={2004}, month=dec, pages={53015–53022} }

JSON

{
  "indexed": {
    "date-parts": [
      [
        2024,
        9,
        12
      ]
    ],
    "date-time": "2024-09-12T20:34:14Z",
    "timestamp": 1726173254166
  },
  "reference-count": 43,
  "publisher": "Elsevier BV",
  "issue": "51",
  "license": [
    {
      "start": {
        "date-parts": [
          [
            2004,
            12,
            1
          ]
        ],
        "date-time": "2004-12-01T00:00:00Z",
        "timestamp": 1101859200000
      },
      "content-version": "tdm",
      "delay-in-days": 0,
      "URL": "https://www.elsevier.com/tdm/userlicense/1.0/"
    },
    {
      "start": {
        "date-parts": [
          [
            2020,
            10,
            21
          ]
        ],
        "date-time": "2020-10-21T00:00:00Z",
        "timestamp": 1603238400000
      },
      "content-version": "vor",
      "delay-in-days": 5803,
      "URL": "http://creativecommons.org/licenses/by/4.0/"
    }
  ],
  "content-domain": {
    "domain": [],
    "crossmark-restriction": false
  },
  "published-print": {
    "date-parts": [
      [
        2004,
        12
      ]
    ]
  },
  "DOI": "10.1074/jbc.m410233200",
  "type": "journal-article",
  "created": {
    "date-parts": [
      [
        2004,
        10,
        8
      ]
    ],
    "date-time": "2004-10-08T00:12:48Z",
    "timestamp": 1097194368000
  },
  "page": "53015-53022",
  "source": "Crossref",
  "is-referenced-by-count": 187,
  "title": "Phosphorylation of p53 on Key Serines Is Dispensable for Transcriptional Activation and Apoptosis",
  "prefix": "10.1016",
  "volume": "279",
  "author": [
    {
      "given": "Thelma",
      "family": "Thompson",
      "sequence": "first",
      "affiliation": []
    },
    {
      "given": "Christian",
      "family": "Tovar",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "Hong",
      "family": "Yang",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "Daisy",
      "family": "Carvajal",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "Binh T.",
      "family": "Vu",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "Qunli",
      "family": "Xu",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "Geoffrey M.",
      "family": "Wahl",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "David C.",
      "family": "Heimbrook",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "Lyubomir T.",
      "family": "Vassilev",
      "sequence": "additional",
      "affiliation": []
    }
  ],
  "member": "78",
  "reference": [
    {
      "key": "10.1074/jbc.M410233200_bib1",
      "doi-asserted-by": "crossref",
      "first-page": "323",
      "DOI": "10.1016/S0092-8674(00)81871-1",
      "volume": "88",
      "author": "Levine",
      "year": "1997",
      "journal-title": "Cell"
    },
    {
      "key": "10.1074/jbc.M410233200_bib2",
      "doi-asserted-by": "crossref",
      "first-page": "307",
      "DOI": "10.1038/35042675",
      "volume": "408",
      "author": "Vogelstein",
      "year": "2000",
      "journal-title": "Nature"
    },
    {
      "key": "10.1074/jbc.M410233200_bib3",
      "doi-asserted-by": "crossref",
      "first-page": "96",
      "DOI": "10.1007/s000180050273",
      "volume": "55",
      "author": "Freedman",
      "year": "1999",
      "journal-title": "Cell. Mol. Life Sci."
    },
    {
      "key": "10.1074/jbc.M410233200_bib4",
      "doi-asserted-by": "crossref",
      "first-page": "49",
      "DOI": "10.1016/S1044-579X(02)00099-8",
      "volume": "13",
      "author": "Michael",
      "year": "2003",
      "journal-title": "Semin. Cancer Biol."
    },
    {
      "key": "10.1074/jbc.M410233200_bib5",
      "doi-asserted-by": "crossref",
      "first-page": "164",
      "DOI": "10.1016/S0955-0674(03)00003-6",
      "volume": "15",
      "author": "Brooks",
      "year": "2003",
      "journal-title": "Curr. Opin. Cell Biol."
    },
    {
      "key": "10.1074/jbc.M410233200_bib6",
      "doi-asserted-by": "crossref",
      "first-page": "1547",
      "DOI": "10.1038/sj.emboj.7600145",
      "volume": "23",
      "author": "Stommel",
      "year": "2004",
      "journal-title": "EMBO J."
    },
    {
      "key": "10.1074/jbc.M410233200_bib7",
      "doi-asserted-by": "crossref",
      "first-page": "2764",
      "DOI": "10.1046/j.1432-1327.2001.02225.x",
      "volume": "268",
      "author": "Apella",
      "year": "2001",
      "journal-title": "Eur. J. Biochem."
    },
    {
      "key": "10.1074/jbc.M410233200_bib8",
      "doi-asserted-by": "crossref",
      "first-page": "7656",
      "DOI": "10.1038/sj.onc.1203013",
      "volume": "18",
      "author": "Jimenez",
      "year": "1999",
      "journal-title": "Oncogene"
    },
    {
      "key": "10.1074/jbc.M410233200_bib9",
      "doi-asserted-by": "crossref",
      "first-page": "208",
      "DOI": "10.1038/sj.neo.7900073",
      "volume": "2",
      "author": "Ljungman",
      "year": "2000",
      "journal-title": "Neoplasia"
    },
    {
      "key": "10.1074/jbc.M410233200_bib10",
      "doi-asserted-by": "crossref",
      "first-page": "2831",
      "DOI": "10.1101/gad.12.18.2831",
      "volume": "12",
      "author": "Sakaguchi",
      "year": "1998",
      "journal-title": "Genes Dev."
    },
    {
      "key": "10.1074/jbc.M410233200_bib11",
      "doi-asserted-by": "crossref",
      "first-page": "133",
      "DOI": "10.1042/bj3420133",
      "volume": "342",
      "author": "Craig",
      "year": "1999",
      "journal-title": "Biochem. J."
    },
    {
      "key": "10.1074/jbc.M410233200_bib12",
      "doi-asserted-by": "crossref",
      "first-page": "491",
      "DOI": "10.1016/S0022-2836(02)00852-5",
      "volume": "323",
      "author": "Schon",
      "year": "2002",
      "journal-title": "J. Mol. Biol."
    },
    {
      "key": "10.1074/jbc.M410233200_bib13",
      "doi-asserted-by": "crossref",
      "first-page": "7666",
      "DOI": "10.1038/sj.onc.1202951",
      "volume": "18",
      "author": "Meek",
      "year": "1999",
      "journal-title": "Oncogene"
    },
    {
      "key": "10.1074/jbc.M410233200_bib14",
      "doi-asserted-by": "crossref",
      "first-page": "88",
      "DOI": "10.1038/376088a0",
      "volume": "376",
      "author": "Wang",
      "year": "1995",
      "journal-title": "Nature"
    },
    {
      "key": "10.1074/jbc.M410233200_bib15",
      "doi-asserted-by": "crossref",
      "first-page": "29380",
      "DOI": "10.1074/jbc.271.46.29380",
      "volume": "271",
      "author": "Hao",
      "year": "1996",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "10.1074/jbc.M410233200_bib16",
      "doi-asserted-by": "crossref",
      "first-page": "10117",
      "DOI": "10.1021/bi970759w",
      "volume": "36",
      "author": "Sakaguchi",
      "year": "1997",
      "journal-title": "Biochemistry"
    },
    {
      "key": "10.1074/jbc.M410233200_bib17",
      "doi-asserted-by": "crossref",
      "first-page": "33048",
      "DOI": "10.1074/jbc.273.49.33048",
      "volume": "273",
      "author": "Lambert",
      "year": "1998",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "10.1074/jbc.M410233200_bib18",
      "doi-asserted-by": "crossref",
      "first-page": "7002",
      "DOI": "10.1093/emboj/18.24.7002",
      "volume": "18",
      "author": "Dumaz",
      "year": "1999",
      "journal-title": "EMBO J."
    },
    {
      "key": "10.1074/jbc.M410233200_bib19",
      "doi-asserted-by": "crossref",
      "first-page": "1202",
      "DOI": "10.1128/MCB.19.2.1202",
      "volume": "19",
      "author": "Liu",
      "year": "1999",
      "journal-title": "Mol. Cell. Biol."
    },
    {
      "key": "10.1074/jbc.M410233200_bib20",
      "doi-asserted-by": "crossref",
      "first-page": "11",
      "DOI": "10.1038/ncb714",
      "volume": "4",
      "author": "D'Orazi",
      "year": "2002",
      "journal-title": "Nat. Cell Biol."
    },
    {
      "key": "10.1074/jbc.M410233200_bib21",
      "doi-asserted-by": "crossref",
      "first-page": "12491",
      "DOI": "10.1074/jbc.C200093200",
      "volume": "277",
      "author": "Saito",
      "year": "2002",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "10.1074/jbc.M410233200_bib22",
      "doi-asserted-by": "crossref",
      "first-page": "849",
      "DOI": "10.1038/nature01116",
      "volume": "419",
      "author": "Zheng",
      "year": "2002",
      "journal-title": "Nature"
    },
    {
      "key": "10.1074/jbc.M410233200_bib23",
      "doi-asserted-by": "crossref",
      "first-page": "853",
      "DOI": "10.1038/nature01120",
      "volume": "419",
      "author": "Zacchi",
      "year": "2002",
      "journal-title": "Nature"
    },
    {
      "key": "10.1074/jbc.M410233200_bib24",
      "doi-asserted-by": "crossref",
      "first-page": "1751",
      "DOI": "10.1128/MCB.19.3.1751",
      "volume": "19",
      "author": "Ashcroft",
      "year": "1999",
      "journal-title": "Mol. Cell. Biol."
    },
    {
      "key": "10.1074/jbc.M410233200_bib25",
      "doi-asserted-by": "crossref",
      "first-page": "2441",
      "DOI": "10.1128/MCB.22.8.2441-2449.2002",
      "volume": "22",
      "author": "Wu",
      "year": "2002",
      "journal-title": "Mol. Cell. Biol."
    },
    {
      "key": "10.1074/jbc.M410233200_bib26",
      "doi-asserted-by": "crossref",
      "first-page": "41028",
      "DOI": "10.1074/jbc.M306938200",
      "volume": "278",
      "author": "Chao",
      "year": "2003",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "10.1074/jbc.M410233200_bib27",
      "doi-asserted-by": "crossref",
      "first-page": "976",
      "DOI": "10.1128/MCB.24.3.976-984.2004",
      "volume": "24",
      "author": "Sluss",
      "year": "2004",
      "journal-title": "Mol. Cell. Biol."
    },
    {
      "key": "10.1074/jbc.M410233200_bib28",
      "doi-asserted-by": "crossref",
      "first-page": "844",
      "DOI": "10.1126/science.1092472",
      "volume": "303",
      "author": "Vassilev",
      "year": "2004",
      "journal-title": "Science"
    },
    {
      "key": "10.1074/jbc.M410233200_bib29",
      "doi-asserted-by": "crossref",
      "first-page": "7382",
      "DOI": "10.1073/pnas.96.13.7382",
      "volume": "96",
      "author": "Ahrendt",
      "year": "1999",
      "journal-title": "Proc. Natl. Acad. Sci. U. S. A."
    },
    {
      "key": "10.1074/jbc.M410233200_bib30",
      "doi-asserted-by": "crossref",
      "first-page": "817",
      "DOI": "10.1016/0092-8674(93)90500-P",
      "volume": "75",
      "author": "el-Deiry",
      "year": "1993",
      "journal-title": "Cell"
    },
    {
      "key": "10.1074/jbc.M410233200_bib31",
      "doi-asserted-by": "crossref",
      "first-page": "689",
      "DOI": "10.1002/bies.950151008",
      "volume": "15",
      "author": "Picksley",
      "year": "1993",
      "journal-title": "Bioessays"
    },
    {
      "key": "10.1074/jbc.M410233200_bib32",
      "doi-asserted-by": "crossref",
      "first-page": "109",
      "DOI": "10.1073/pnas.97.1.109",
      "volume": "97",
      "author": "Tan",
      "year": "2000",
      "journal-title": "Proc. Natl. Acad. Sci. U. S. A."
    },
    {
      "key": "10.1074/jbc.M410233200_bib33",
      "first-page": "1023",
      "volume": "2",
      "author": "Yang",
      "year": "2003",
      "journal-title": "Mol. Cancer Ther."
    },
    {
      "key": "10.1074/jbc.M410233200_bib34",
      "doi-asserted-by": "crossref",
      "first-page": "703",
      "DOI": "10.1016/0092-8674(94)90534-7",
      "volume": "78",
      "author": "Symonds",
      "year": "1994",
      "journal-title": "Cell"
    },
    {
      "key": "10.1074/jbc.M410233200_bib35",
      "doi-asserted-by": "crossref",
      "first-page": "137",
      "DOI": "10.1007/s00109-001-0293-3",
      "volume": "80",
      "author": "Schmitt",
      "year": "2002",
      "journal-title": "J. Mol. Med."
    },
    {
      "key": "10.1074/jbc.M410233200_bib36",
      "doi-asserted-by": "crossref",
      "first-page": "220",
      "DOI": "10.1038/370220a0",
      "volume": "370",
      "author": "Caelles",
      "year": "1994",
      "journal-title": "Nature"
    },
    {
      "issue": "Suppl. 3",
      "key": "10.1074/jbc.M410233200_bib37",
      "first-page": "337",
      "volume": "11",
      "author": "Haupt",
      "year": "1997",
      "journal-title": "Leukemia"
    },
    {
      "key": "10.1074/jbc.M410233200_bib38",
      "first-page": "323",
      "volume": "85",
      "author": "Steensma",
      "year": "2003",
      "journal-title": "Methods Mol. Med."
    },
    {
      "key": "10.1074/jbc.M410233200_bib39",
      "doi-asserted-by": "crossref",
      "first-page": "31",
      "DOI": "10.2174/0929867013373994",
      "volume": "8",
      "author": "Perego",
      "year": "2001",
      "journal-title": "Curr. Med. Chem."
    },
    {
      "key": "10.1074/jbc.M410233200_bib40",
      "doi-asserted-by": "crossref",
      "first-page": "66",
      "DOI": "10.1006/excr.2001.5314",
      "volume": "270",
      "author": "Xirodimas",
      "year": "2001",
      "journal-title": "Exp. Cell Res."
    },
    {
      "key": "10.1074/jbc.M410233200_bib41",
      "doi-asserted-by": "crossref",
      "first-page": "37536",
      "DOI": "10.1074/jbc.M305135200",
      "volume": "278",
      "author": "Saito",
      "year": "2003",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "10.1074/jbc.M410233200_bib42",
      "doi-asserted-by": "crossref",
      "first-page": "4477",
      "DOI": "10.1038/sj.onc.1207575",
      "volume": "23",
      "author": "Jackson",
      "year": "2004",
      "journal-title": "Oncogene"
    },
    {
      "key": "10.1074/jbc.M410233200_bib43",
      "doi-asserted-by": "crossref",
      "first-page": "577",
      "DOI": "10.1016/S1097-2765(03)00050-9",
      "volume": "11",
      "author": "Mihara",
      "year": "2003",
      "journal-title": "Mol. Cell"
    }
  ],
  "container-title": "Journal of Biological Chemistry",
  "original-title": [],
  "language": "en",
  "link": [
    {
      "URL": "https://api.elsevier.com/content/article/PII:S0021925818819354?httpAccept=text/xml",
      "content-type": "text/xml",
      "content-version": "vor",
      "intended-application": "text-mining"
    },
    {
      "URL": "https://api.elsevier.com/content/article/PII:S0021925818819354?httpAccept=text/plain",
      "content-type": "text/plain",
      "content-version": "vor",
      "intended-application": "text-mining"
    },
    {
      "URL": "https://syndication.highwire.org/content/doi/10.1074/jbc.M410233200",
      "content-type": "unspecified",
      "content-version": "vor",
      "intended-application": "similarity-checking"
    }
  ],
  "deposited": {
    "date-parts": [
      [
        2022,
        1,
        2
      ]
    ],
    "date-time": "2022-01-02T03:29:57Z",
    "timestamp": 1641094197000
  },
  "score": 1,
  "resource": {
    "primary": {
      "URL": "https://linkinghub.elsevier.com/retrieve/pii/S0021925818819354"
    }
  },
  "subtitle": [],
  "short-title": [],
  "issued": {
    "date-parts": [
      [
        2004,
        12
      ]
    ]
  },
  "references-count": 43,
  "journal-issue": {
    "issue": "51",
    "published-print": {
      "date-parts": [
        [
          2004,
          12
        ]
      ]
    }
  },
  "alternative-id": [
    "S0021925818819354"
  ],
  "URL": "http://dx.doi.org/10.1074/jbc.M410233200",
  "relation": {},
  "ISSN": [
    "0021-9258"
  ],
  "subject": [],
  "container-title-short": "Journal of Biological Chemistry",
  "published": {
    "date-parts": [
      [
        2004,
        12
      ]
    ]
  }
}