DOI: 10.1074/jbc.m409604200. Substrate Specificity and Kinetic Mechanism of Mammalian G9a Histone H3 Methyltransferase

Substrate Specificity and Kinetic Mechanism of Mammalian G9a Histone H3 Methyltransferase

10.1074/jbc.m409604200

Crossref journal-article

Elsevier BV

Journal of Biological Chemistry (78)

Bibliography

Patnaik, D., Chin, H. G., EstÃ¨ve, P.-O., Benner, J., Jacobsen, S. E., & Pradhan, S. (2004). Substrate Specificity and Kinetic Mechanism of Mammalian G9a Histone H3 Methyltransferase. Journal of Biological Chemistry, 279(51), 53248â53258.

Authors 6

Debasis Patnaik (first)
Hang Gyeong Chin (additional)
Pierre-Olivier Estève (additional)
Jack Benner (additional)
Steven E. Jacobsen (additional)
Sriharsa Pradhan (additional)

References 38 Referenced 126

10.1038/47412 / Nature by Strahl (2000)
10.1016/S0092-8674(00)81063-6 / Cell by Brownell (1996)
10.1016/S0021-9258(19)45074-6 / J. Biol. Chem. by Borun (1972)
10.1038/35020506 / Nature by Rea (2000)
10.1126/science.1064150 / Science by Noma (2001)
10.1016/j.ceb.2004.03.005 / Curr. Opin. Cell Biol. by Heard (2004)
10.1073/pnas.0306641101 / Proc. Natl. Acad. Sci. U. S. A. by Kondo (2004)
10.1038/35104508 / Nature by Tamaru (2001)
10.1038/nature731 / Nature by Jackson (2002)
10.1093/emboj/cdf657 / EMBO J. by Soppe (2002)
10.1073/pnas.1432939100 / Proc. Natl. Acad. Sci. U. S. A. by Tariq (2003)
10.1016/S0960-9822(03)00432-9 / Curr. Biol. by Lehnertz (2003)
10.1016/S1535-6108(02)00234-9 / Cancer Cell by Bachman (2003)
10.1126/science.1060118 / Science by Nakayama (2001)
10.1002/j.1460-2075.1994.tb06693.x / EMBO J. by Tschiersch (1994)
10.1101/gad.973302 / Genes Dev. by Schultz (2002)
10.1038/sj.onc.1204998 / Oncogene by Yang (2002)
10.1074/jbc.M101914200 / J. Biol. Chem. by Tachibana (2001)
10.1021/bi035964s / Biochemistry by Eskeland (2004)
10.1016/S1097-2765(03)00477-5 / Mol. Cell. by Peters (2003)
10.1074/jbc.M211753200 / J. Biol. Chem. by Xin (2003)
10.1016/S0092-8674(02)01010-3 / Cell by Yeates (2002)
10.1093/nar/25.22.4666 / Nucleic Acids Res. by Pradhan (1997)
{'key': '10.1074/jbc.M409604200_bib24', 'series-title': 'Baculovirus Expression Vectors: A Laboratory Manual', 'first-page': '124', 'author': "O'Reilly", 'year': '1992'} / Baculovirus Expression Vectors: A Laboratory Manual by O'Reilly (1992)
10.1016/S0021-9258(18)61070-1 / J. Biol. Chem. by Matsudaira (1987)
10.1128/jb.173.16.5207-5219.1991 / J. Bacteriol. by Waite-Rees (1992)
{'key': '10.1074/jbc.M409604200_bib27', 'series-title': 'Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-state Enzyme Systems', 'author': 'Segal', 'year': '1975'} / Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-state Enzyme Systems by Segal (1975)
{'key': '10.1074/jbc.M409604200_bib28', 'series-title': 'Protein Sequence Analysis', 'first-page': '1', 'author': 'Crankshaw', 'year': '1993'} / Protein Sequence Analysis by Crankshaw (1993)
10.1021/bi9810609 / Biochemistry by Flynn (1998)
10.1038/nature01378 / Nature by Xiao (2003)
10.1016/S1097-2765(03)00479-9 / Mol. Cell by Rice (2003)
10.1016/S1097-2765(03)00224-7 / Mol. Cell by Zhang (2003)
10.1038/nsb946 / Nat. Struct. Biol. by Trievel (2003)
10.1016/S0092-8674(02)01000-0 / Cell by Trievel (2002)
10.1016/S1097-2765(01)00405-1 / Mol. Cell by Wang (2001)
10.1074/jbc.274.46.33011 / J. Biol. Chem. by Bacolla (1999)
10.1074/jbc.M101429200 / J. Biol. Chem. by Vilkaitis (2001)
10.1074/jbc.M213213200 / J. Biol. Chem. by Malygin (2003)

Dates

Type	When
Created	20 years, 10 months ago (Oct. 14, 2004, 8:12 p.m.)
Deposited	3 years, 7 months ago (Jan. 1, 2022, 10:30 p.m.)
Indexed	3 months ago (May 19, 2025, 5:04 a.m.)
Issued	20 years, 8 months ago (Dec. 1, 2004)
Published	20 years, 8 months ago (Dec. 1, 2004)
Published Print	20 years, 8 months ago (Dec. 1, 2004)

Funders 0

None

BibTeX

@article{Patnaik_2004, title={Substrate Specificity and Kinetic Mechanism of Mammalian G9a Histone H3 Methyltransferase}, volume={279}, ISSN={0021-9258}, url={http://dx.doi.org/10.1074/jbc.m409604200}, DOI={10.1074/jbc.m409604200}, number={51}, journal={Journal of Biological Chemistry}, publisher={Elsevier BV}, author={Patnaik, Debasis and Chin, Hang Gyeong and Estève, Pierre-Olivier and Benner, Jack and Jacobsen, Steven E. and Pradhan, Sriharsa}, year={2004}, month=dec, pages={53248–53258} }

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      "series-title": "Baculovirus Expression Vectors: A Laboratory Manual",
      "first-page": "124",
      "author": "O'Reilly",
      "year": "1992"
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      "DOI": "10.1016/S0021-9258(18)61070-1",
      "volume": "262",
      "author": "Matsudaira",
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      "DOI": "10.1021/bi9810609",
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      "author": "Zhang",
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