DOI: 10.1074/jbc.m303302200. Certain Metals Trigger Fibrillation of Methionine-oxidized α-Synuclein

Certain Metals Trigger Fibrillation of Methionine-oxidized α-Synuclein

10.1074/jbc.m303302200

Crossref journal-article

Elsevier BV

Journal of Biological Chemistry (78)

Bibliography

Yamin, G., Glaser, C. B., Uversky, V. N., & Fink, A. L. (2003). Certain Metals Trigger Fibrillation of Methionine-oxidized Î±-Synuclein. Journal of Biological Chemistry, 278(30), 27630â27635.

Authors 4

Ghiam Yamin (first)
Charles B. Glaser (additional)
Vladimir N. Uversky (additional)
Anthony L. Fink (additional)

References 41 Referenced 160

{'key': '10.1074/jbc.M303302200_bib1', 'series-title': 'Handbuch der Neurologie', 'first-page': '920', 'author': 'Lewy', 'year': '1912'} / Handbuch der Neurologie by Lewy (1912)
10.1097/00005072-199603000-00001 / J. Neuropathol. Exp. Neurol. by Forno (1996)
10.1038/42166 / Nature by Spillantini (1997)
10.1126/science.276.5321.2045 / Science by Polymeropoulos (1997)
10.1038/ng0298-106 / Nat. Genet. by Kruger (1998)
10.1126/science.287.5456.1265 / Science by Masliah (2000)
10.1038/35006074 / Nature by Feany (2000)
10.1523/JNEUROSCI.08-08-02804.1988 / J. Neurosci. by Maroteaux (1988)
10.1016/0896-6273(95)90302-X / Neuron by Iwai (1995)
10.1021/bi961799n / Biochemistry by Weinreb (1996)
10.1074/jbc.M010907200 / J. Biol. Chem. by Uversky (2001)
10.1002/1097-0134(20001115)41:3<415::AID-PROT130>3.0.CO;2-7 / Proteins by Uversky (2000)
10.1038/3311 / Nat. Med. by Conway (1998)
10.1073/pnas.97.2.571 / Proc. Natl. Acad. Sci. U. S. A. by Conway (2000)
10.1016/S0014-5793(98)01146-6 / FEBS Lett. by Crowther (1998)
10.1074/jbc.274.12.7619 / J. Biol. Chem. by Giasson (1998)
10.1074/jbc.274.28.19509 / J. Biol. Chem. by Wood (1999)
10.1073/pnas.97.9.4897 / Proc. Natl. Acad. Sci. U. S. A. by Serpell (2000)
10.1001/jama.281.4.341 / JAMA (J. Am. Med. Assoc.) by Tanner (1999)
10.1016/0166-2236(89)90135-5 / Trends Neurosci. by Tanner (1989)
10.1074/jbc.M105343200 / J. Biol. Chem. by Uversky (2001)
10.1016/S0014-5793(01)02597-2 / FEBS Lett. by Uversky (2001)
10.1074/jbc.C100560200 / J. Biol. Chem. by Manning-Bog (2002)
10.1016/S0161-813X(02)00067-0 / Neurotoxicology by Uversky (2002)
10.1002/ana.410320714 / Ann. Neurol. by Jenner (1992)
10.1073/pnas.93.7.2696 / Proc. Natl. Acad. Sci. U. S. A. by Yoritaka (1996)
10.1097/00005072-199804000-00006 / J. Neuropathol. Exp. Neurol. by Good (1998)
10.1016/S0002-9440(10)64781-5 / Am. J. Pathol. by Duda (2000)
10.1126/science.290.5493.985 / Science by Giasson (2000)
10.1006/abbi.2000.1822 / Arch. Biochem. Biophys. by Paik (2000)
10.1126/science.1063522 / Science by Conway (2001)
10.1021/bi026528t / Biochemistry by Krishnan (2003)
10.1016/S0014-5793(02)02638-8 / FEBS Lett. by Uversky (2002)
{'key': '10.1074/jbc.M303302200_bib34', 'first-page': '768', 'volume': '62', 'author': 'Naiki', 'year': '1990', 'journal-title': 'Lab. Invest.'} / Lab. Invest. by Naiki (1990)
10.1016/S0196-9781(02)00066-9 / Peptides (Elmsford) by Butterfield (2002)
10.1074/jbc.C100551200 / J. Biol. Chem. by Uversky (2001)
10.1021/ja01497a003 / J. Amer. Chem. Soc. by Cotton (1960)
10.1073/pnas.93.26.15036 / Proc. Natl. Acad. Sci. U. S. A. by Levine (1996)
10.1016/0147-6513(94)90002-7 / Ecotoxicol. Environ. Saf. by Reddy (1994)
10.1016/S0014-5793(99)00888-1 / FEBS Lett. by Sharov (1999)
10.1016/S0891-5849(00)00400-7 / Free Radic. Biol. Med. by Sharov (2000)

Dates

Type	When
Created	22 years, 1 month ago (July 18, 2003, 4:02 p.m.)
Deposited	3 years, 7 months ago (Jan. 5, 2022, 4:22 p.m.)
Indexed	1 week ago (Aug. 29, 2025, 6:14 a.m.)
Issued	22 years, 2 months ago (July 1, 2003)
Published	22 years, 2 months ago (July 1, 2003)
Published Print	22 years, 2 months ago (July 1, 2003)

Funders 0

None

BibTeX

@article{Yamin_2003, title={Certain Metals Trigger Fibrillation of Methionine-oxidized α-Synuclein}, volume={278}, ISSN={0021-9258}, url={http://dx.doi.org/10.1074/jbc.m303302200}, DOI={10.1074/jbc.m303302200}, number={30}, journal={Journal of Biological Chemistry}, publisher={Elsevier BV}, author={Yamin, Ghiam and Glaser, Charles B. and Uversky, Vladimir N. and Fink, Anthony L.}, year={2003}, month=jul, pages={27630–27635} }

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      "first-page": "1265",
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      "author": "Masliah",
      "year": "2000",
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    {
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      "volume": "8",
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    },
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      "first-page": "467",
      "DOI": "10.1016/0896-6273(95)90302-X",
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      "author": "Iwai",
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    {
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      "first-page": "13709",
      "DOI": "10.1021/bi961799n",
      "volume": "35",
      "author": "Weinreb",
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      "journal-title": "Biochemistry"
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    {
      "key": "10.1074/jbc.M303302200_bib11",
      "doi-asserted-by": "crossref",
      "first-page": "10737",
      "DOI": "10.1074/jbc.M010907200",
      "volume": "276",
      "author": "Uversky",
      "year": "2001",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "10.1074/jbc.M303302200_bib12",
      "doi-asserted-by": "crossref",
      "first-page": "415",
      "DOI": "10.1002/1097-0134(20001115)41:3<415::AID-PROT130>3.0.CO;2-7",
      "volume": "41",
      "author": "Uversky",
      "year": "2000",
      "journal-title": "Proteins"
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    {
      "key": "10.1074/jbc.M303302200_bib13",
      "doi-asserted-by": "crossref",
      "first-page": "1318",
      "DOI": "10.1038/3311",
      "volume": "4",
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      "journal-title": "Nat. Med."
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      "author": "Conway",
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      "journal-title": "FEBS Lett."
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      "first-page": "7619",
      "DOI": "10.1074/jbc.274.12.7619",
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    },
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      "journal-title": "J. Biol. Chem."
    },
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      "volume": "97",
      "author": "Serpell",
      "year": "2000",
      "journal-title": "Proc. Natl. Acad. Sci. U. S. A."
    },
    {
      "key": "10.1074/jbc.M303302200_bib19",
      "doi-asserted-by": "crossref",
      "first-page": "341",
      "DOI": "10.1001/jama.281.4.341",
      "volume": "281",
      "author": "Tanner",
      "year": "1999",
      "journal-title": "JAMA (J. Am. Med. Assoc.)"
    },
    {
      "key": "10.1074/jbc.M303302200_bib20",
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      "first-page": "49",
      "DOI": "10.1016/0166-2236(89)90135-5",
      "volume": "12",
      "author": "Tanner",
      "year": "1989",
      "journal-title": "Trends Neurosci."
    },
    {
      "key": "10.1074/jbc.M303302200_bib21",
      "doi-asserted-by": "crossref",
      "first-page": "44284",
      "DOI": "10.1074/jbc.M105343200",
      "volume": "276",
      "author": "Uversky",
      "year": "2001",
      "journal-title": "J. Biol. Chem."
    },
    {
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      "DOI": "10.1016/S0014-5793(01)02597-2",
      "volume": "500",
      "author": "Uversky",
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      "journal-title": "FEBS Lett."
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    {
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      "author": "Manning-Bog",
      "year": "2002",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "10.1074/jbc.M303302200_bib24",
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      "first-page": "527",
      "DOI": "10.1016/S0161-813X(02)00067-0",
      "volume": "23",
      "author": "Uversky",
      "year": "2002",
      "journal-title": "Neurotoxicology"
    },
    {
      "issue": "suppl.",
      "key": "10.1074/jbc.M303302200_bib25",
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      "first-page": "S82",
      "DOI": "10.1002/ana.410320714",
      "volume": "32",
      "author": "Jenner",
      "year": "1992",
      "journal-title": "Ann. Neurol."
    },
    {
      "key": "10.1074/jbc.M303302200_bib26",
      "doi-asserted-by": "crossref",
      "first-page": "2696",
      "DOI": "10.1073/pnas.93.7.2696",
      "volume": "93",
      "author": "Yoritaka",
      "year": "1996",
      "journal-title": "Proc. Natl. Acad. Sci. U. S. A."
    },
    {
      "key": "10.1074/jbc.M303302200_bib27",
      "doi-asserted-by": "crossref",
      "first-page": "338",
      "DOI": "10.1097/00005072-199804000-00006",
      "volume": "57",
      "author": "Good",
      "year": "1998",
      "journal-title": "J. Neuropathol. Exp. Neurol."
    },
    {
      "key": "10.1074/jbc.M303302200_bib28",
      "doi-asserted-by": "crossref",
      "first-page": "1439",
      "DOI": "10.1016/S0002-9440(10)64781-5",
      "volume": "157",
      "author": "Duda",
      "year": "2000",
      "journal-title": "Am. J. Pathol."
    },
    {
      "key": "10.1074/jbc.M303302200_bib29",
      "doi-asserted-by": "crossref",
      "first-page": "985",
      "DOI": "10.1126/science.290.5493.985",
      "volume": "290",
      "author": "Giasson",
      "year": "2000",
      "journal-title": "Science"
    },
    {
      "key": "10.1074/jbc.M303302200_bib30",
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      "first-page": "269",
      "DOI": "10.1006/abbi.2000.1822",
      "volume": "378",
      "author": "Paik",
      "year": "2000",
      "journal-title": "Arch. Biochem. Biophys."
    },
    {
      "key": "10.1074/jbc.M303302200_bib31",
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      "first-page": "1346",
      "DOI": "10.1126/science.1063522",
      "volume": "294",
      "author": "Conway",
      "year": "2001",
      "journal-title": "Science"
    },
    {
      "key": "10.1074/jbc.M303302200_bib32",
      "doi-asserted-by": "crossref",
      "first-page": "829",
      "DOI": "10.1021/bi026528t",
      "volume": "42",
      "author": "Krishnan",
      "year": "2003",
      "journal-title": "Biochemistry"
    },
    {
      "key": "10.1074/jbc.M303302200_bib33",
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      "first-page": "239",
      "DOI": "10.1016/S0014-5793(02)02638-8",
      "volume": "517",
      "author": "Uversky",
      "year": "2002",
      "journal-title": "FEBS Lett."
    },
    {
      "key": "10.1074/jbc.M303302200_bib34",
      "first-page": "768",
      "volume": "62",
      "author": "Naiki",
      "year": "1990",
      "journal-title": "Lab. Invest."
    },
    {
      "key": "10.1074/jbc.M303302200_bib35",
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      "first-page": "1299",
      "DOI": "10.1016/S0196-9781(02)00066-9",
      "volume": "23",
      "author": "Butterfield",
      "year": "2002",
      "journal-title": "Peptides (Elmsford)"
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      "first-page": "43495",
      "DOI": "10.1074/jbc.C100551200",
      "volume": "276",
      "author": "Uversky",
      "year": "2001",
      "journal-title": "J. Biol. Chem."
    },
    {
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      "first-page": "2986",
      "DOI": "10.1021/ja01497a003",
      "volume": "82",
      "author": "Cotton",
      "year": "1960",
      "journal-title": "J. Amer. Chem. Soc."
    },
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      "author": "Levine",
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      "first-page": "255",
      "DOI": "10.1016/0147-6513(94)90002-7",
      "volume": "29",
      "author": "Reddy",
      "year": "1994",
      "journal-title": "Ecotoxicol. Environ. Saf."
    },
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      "first-page": "247",
      "DOI": "10.1016/S0014-5793(99)00888-1",
      "volume": "455",
      "author": "Sharov",
      "year": "1999",
      "journal-title": "FEBS Lett."
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      "first-page": "986",
      "DOI": "10.1016/S0891-5849(00)00400-7",
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      "author": "Sharov",
      "year": "2000",
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  "subtitle": [],
  "short-title": [],
  "issued": {
    "date-parts": [
      [
        2003,
        7
      ]
    ]
  },
  "references-count": 41,
  "journal-issue": {
    "issue": "30",
    "published-print": {
      "date-parts": [
        [
          2003,
          7
        ]
      ]
    }
  },
  "alternative-id": [
    "S0021925820844822"
  ],
  "URL": "http://dx.doi.org/10.1074/jbc.M303302200",
  "relation": {},
  "ISSN": [
    "0021-9258"
  ],
  "subject": [],
  "container-title-short": "Journal of Biological Chemistry",
  "published": {
    "date-parts": [
      [
        2003,
        7
      ]
    ]
  }
}