DOI: 10.1074/jbc.m202029200. Lateral Dimerization of the E-cadherin Extracellular Domain Is Necessary but Not Sufficient for Adhesive Activity

Lateral Dimerization of the E-cadherin Extracellular Domain Is Necessary but Not Sufficient for Adhesive Activity

10.1074/jbc.m202029200

Crossref journal-article

Elsevier BV

Journal of Biological Chemistry (78)

Bibliography

Ozawa, M. (2002). Lateral Dimerization of the E-cadherin Extracellular Domain Is Necessary but Not Sufficient for Adhesive Activity. Journal of Biological Chemistry, 277(22), 19600â19608.

Authors 1

Masayuki Ozawa (first)

References 44 Referenced 57

10.1126/science.2006419 / Science. by Takeichi (1991)
10.1146/annurev.cb.08.110192.001515 / Annu. Rev. Cell Biol. by Geiger (1992)
10.1016/0168-9525(93)90250-L / Trends Genet. by Kemler (1993)
10.1002/j.1460-2075.1989.tb03563.x / EMBO J. by Ozawa (1989)
10.1073/pnas.87.11.4246 / Proc. Natl. Acad. Sci. U. S. A. by Ozawa (1990)
{'key': '10.1074/jbc.M202029200_bib6', 'first-page': '8333', 'volume': '14', 'author': 'Reynolds', 'year': '1994', 'journal-title': 'Mol. Cell. Biol.'} / Mol. Cell. Biol. by Reynolds (1994)
10.1083/jcb.125.6.1327 / J. Cell Biol. by Hinck (1994)
10.1083/jcb.142.6.1605 / J. Cell Biol. by Ozawa (1998)
10.1083/jcb.141.3.779 / J. Cell Biol. by Yap (1998)
10.1083/jcb.145.3.551 / J. Cell Biol. by Aono (1999)
10.1074/jbc.274.30.21409 / J. Biol. Chem. by Ohkubo (1999)
10.1083/jcb.148.1.189 / J. Cell Biol. by Thoreson (2000)
10.1242/jcs.114.3.503 / J. Cell Sci. by Ozawa (2001)
10.1111/j.1432-1033.1994.tb19080.x / Eur. J. Biochem. by Pokutta (1994)
10.1038/380360a0 / Nature. by Nagar (1996)
10.1016/0092-8674(90)90506-A / Cell. by Ozawa (1990)
10.1016/0092-8674(90)90222-Z / Cell. by Nose (1990)
10.1126/science.7824937 / Science. by Overduin (1995)
10.1038/374327a0 / Nature. by Shapiro (1995)
10.1016/S0896-6273(00)80496-1 / Neuron. by Tamura (1998)
10.1093/emboj/18.7.1738 / EMBO J. by Pertz (1999)
10.1016/S0014-5793(97)01333-1 / FEBS Lett. by Alattia (1997)
10.1021/bi9705624 / Biochemistry. by Koch (1997)
10.1002/j.1460-2075.1996.tb00719.x / EMBO J. by Tomschy (1996)
10.1038/7542 / Nat. Struct. Biol. by Takeda (1999)
10.1073/pnas.070052697 / Proc. Natl. Acad. Sci. U. S. A. by Baumgartner (2000)
10.1083/jcb.135.2.487 / J. Cell Biol. by Brieher (1996)
10.1016/S0960-9822(06)00154-0 / Curr. Biol. by Yap (1997)
10.1083/jcb.142.3.837 / J. Cell Biol. by Chitaev (1998)
10.1016/0378-1119(91)90434-D / Gene (Amst.). by Niwa (1991)
10.1083/jcb.111.4.1645 / J. Cell Biol. by Ozawa (1990)
10.1083/jcb.148.3.579 / J. Cell Biol. by Shan (2000)
10.1038/42408 / Nature. by Simons (1997)
10.1242/jcs.112.10.1621 / J. Cell Sci. by Nieman (1999)
10.1152/ajpcell.1999.276.2.C404 / Am. J. Physiol. by Troxell (1999)
10.1074/jbc.M101712200 / J. Biol. Chem. by Corps (2001)
10.1016/0014-5793(94)00467-6 / FEBS Lett. by Lemmon (1994)
10.1242/jcs.112.23.4415 / J. Cell Sci. by Huber (1999)
10.1083/jcb.200103143 / J. Cell Biol. by Chappuis-Flament (2001)
10.1016/S0092-8674(00)81279-9 / Cell. by Gumbiner (1996)
10.1073/pnas.96.21.11820 / Proc. Natl. Acad. Sci. U. S. A. by Sivasankar (1999)
10.1002/j.1460-2075.1987.tb02697.x / EMBO J. by Ringwald (1987)
10.1093/nar/18.19.5896 / Nucleic Acids Res. by Reid (1990)
10.1084/jem.166.5.1548 / J. Exp. Med. by Streuli (1987)

Dates

Type	When
Created	23 years, 1 month ago (July 26, 2002, 11:16 a.m.)
Deposited	3 years, 8 months ago (Jan. 5, 2022, 4:35 p.m.)
Indexed	2 months, 1 week ago (June 26, 2025, 9:29 a.m.)
Issued	23 years, 4 months ago (May 1, 2002)
Published	23 years, 4 months ago (May 1, 2002)
Published Print	23 years, 4 months ago (May 1, 2002)

Funders 0

None

BibTeX

@article{Ozawa_2002, title={Lateral Dimerization of the E-cadherin Extracellular Domain Is Necessary but Not Sufficient for Adhesive Activity}, volume={277}, ISSN={0021-9258}, url={http://dx.doi.org/10.1074/jbc.m202029200}, DOI={10.1074/jbc.m202029200}, number={22}, journal={Journal of Biological Chemistry}, publisher={Elsevier BV}, author={Ozawa, Masayuki}, year={2002}, month=may, pages={19600–19608} }

JSON

{
  "indexed": {
    "date-parts": [
      [
        2025,
        6,
        26
      ]
    ],
    "date-time": "2025-06-26T13:29:09Z",
    "timestamp": 1750944549931
  },
  "reference-count": 44,
  "publisher": "Elsevier BV",
  "issue": "22",
  "license": [
    {
      "start": {
        "date-parts": [
          [
            2002,
            5,
            1
          ]
        ],
        "date-time": "2002-05-01T00:00:00Z",
        "timestamp": 1020211200000
      },
      "content-version": "tdm",
      "delay-in-days": 0,
      "URL": "https://www.elsevier.com/tdm/userlicense/1.0/"
    },
    {
      "start": {
        "date-parts": [
          [
            2020,
            10,
            1
          ]
        ],
        "date-time": "2020-10-01T00:00:00Z",
        "timestamp": 1601510400000
      },
      "content-version": "vor",
      "delay-in-days": 6728,
      "URL": "http://creativecommons.org/licenses/by/4.0/"
    }
  ],
  "content-domain": {
    "domain": [],
    "crossmark-restriction": false
  },
  "published-print": {
    "date-parts": [
      [
        2002,
        5
      ]
    ]
  },
  "DOI": "10.1074/jbc.m202029200",
  "type": "journal-article",
  "created": {
    "date-parts": [
      [
        2002,
        7,
        26
      ]
    ],
    "date-time": "2002-07-26T15:16:37Z",
    "timestamp": 1027696597000
  },
  "page": "19600-19608",
  "source": "Crossref",
  "is-referenced-by-count": 57,
  "title": "Lateral Dimerization of the E-cadherin Extracellular Domain Is Necessary but Not Sufficient for Adhesive Activity",
  "prefix": "10.1016",
  "volume": "277",
  "author": [
    {
      "given": "Masayuki",
      "family": "Ozawa",
      "sequence": "first",
      "affiliation": []
    }
  ],
  "member": "78",
  "reference": [
    {
      "key": "10.1074/jbc.M202029200_bib1",
      "doi-asserted-by": "crossref",
      "first-page": "1451",
      "DOI": "10.1126/science.2006419",
      "volume": "251",
      "author": "Takeichi",
      "year": "1991",
      "journal-title": "Science."
    },
    {
      "key": "10.1074/jbc.M202029200_bib2",
      "doi-asserted-by": "crossref",
      "first-page": "307",
      "DOI": "10.1146/annurev.cb.08.110192.001515",
      "volume": "8",
      "author": "Geiger",
      "year": "1992",
      "journal-title": "Annu. Rev. Cell Biol."
    },
    {
      "key": "10.1074/jbc.M202029200_bib3",
      "doi-asserted-by": "crossref",
      "first-page": "317",
      "DOI": "10.1016/0168-9525(93)90250-L",
      "volume": "9",
      "author": "Kemler",
      "year": "1993",
      "journal-title": "Trends Genet."
    },
    {
      "key": "10.1074/jbc.M202029200_bib4",
      "doi-asserted-by": "crossref",
      "first-page": "1711",
      "DOI": "10.1002/j.1460-2075.1989.tb03563.x",
      "volume": "8",
      "author": "Ozawa",
      "year": "1989",
      "journal-title": "EMBO J."
    },
    {
      "key": "10.1074/jbc.M202029200_bib5",
      "doi-asserted-by": "crossref",
      "first-page": "4246",
      "DOI": "10.1073/pnas.87.11.4246",
      "volume": "87",
      "author": "Ozawa",
      "year": "1990",
      "journal-title": "Proc. Natl. Acad. Sci. U. S. A."
    },
    {
      "key": "10.1074/jbc.M202029200_bib6",
      "first-page": "8333",
      "volume": "14",
      "author": "Reynolds",
      "year": "1994",
      "journal-title": "Mol. Cell. Biol."
    },
    {
      "key": "10.1074/jbc.M202029200_bib7",
      "doi-asserted-by": "crossref",
      "first-page": "1327",
      "DOI": "10.1083/jcb.125.6.1327",
      "volume": "125",
      "author": "Hinck",
      "year": "1994",
      "journal-title": "J. Cell Biol."
    },
    {
      "key": "10.1074/jbc.M202029200_bib8",
      "doi-asserted-by": "crossref",
      "first-page": "1605",
      "DOI": "10.1083/jcb.142.6.1605",
      "volume": "142",
      "author": "Ozawa",
      "year": "1998",
      "journal-title": "J. Cell Biol."
    },
    {
      "key": "10.1074/jbc.M202029200_bib9",
      "doi-asserted-by": "crossref",
      "first-page": "779",
      "DOI": "10.1083/jcb.141.3.779",
      "volume": "141",
      "author": "Yap",
      "year": "1998",
      "journal-title": "J. Cell Biol."
    },
    {
      "key": "10.1074/jbc.M202029200_bib10",
      "doi-asserted-by": "crossref",
      "first-page": "551",
      "DOI": "10.1083/jcb.145.3.551",
      "volume": "145",
      "author": "Aono",
      "year": "1999",
      "journal-title": "J. Cell Biol."
    },
    {
      "key": "10.1074/jbc.M202029200_bib11",
      "doi-asserted-by": "crossref",
      "first-page": "21409",
      "DOI": "10.1074/jbc.274.30.21409",
      "volume": "274",
      "author": "Ohkubo",
      "year": "1999",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "10.1074/jbc.M202029200_bib12",
      "doi-asserted-by": "crossref",
      "first-page": "189",
      "DOI": "10.1083/jcb.148.1.189",
      "volume": "148",
      "author": "Thoreson",
      "year": "2000",
      "journal-title": "J. Cell Biol."
    },
    {
      "key": "10.1074/jbc.M202029200_bib13",
      "doi-asserted-by": "crossref",
      "first-page": "503",
      "DOI": "10.1242/jcs.114.3.503",
      "volume": "114",
      "author": "Ozawa",
      "year": "2001",
      "journal-title": "J. Cell Sci."
    },
    {
      "key": "10.1074/jbc.M202029200_bib14",
      "doi-asserted-by": "crossref",
      "first-page": "1019",
      "DOI": "10.1111/j.1432-1033.1994.tb19080.x",
      "volume": "223",
      "author": "Pokutta",
      "year": "1994",
      "journal-title": "Eur. J. Biochem."
    },
    {
      "key": "10.1074/jbc.M202029200_bib15",
      "doi-asserted-by": "crossref",
      "first-page": "360",
      "DOI": "10.1038/380360a0",
      "volume": "380",
      "author": "Nagar",
      "year": "1996",
      "journal-title": "Nature."
    },
    {
      "key": "10.1074/jbc.M202029200_bib16",
      "doi-asserted-by": "crossref",
      "first-page": "1033",
      "DOI": "10.1016/0092-8674(90)90506-A",
      "volume": "63",
      "author": "Ozawa",
      "year": "1990",
      "journal-title": "Cell."
    },
    {
      "key": "10.1074/jbc.M202029200_bib17",
      "doi-asserted-by": "crossref",
      "first-page": "147",
      "DOI": "10.1016/0092-8674(90)90222-Z",
      "volume": "61",
      "author": "Nose",
      "year": "1990",
      "journal-title": "Cell."
    },
    {
      "key": "10.1074/jbc.M202029200_bib18",
      "doi-asserted-by": "crossref",
      "first-page": "386",
      "DOI": "10.1126/science.7824937",
      "volume": "267",
      "author": "Overduin",
      "year": "1995",
      "journal-title": "Science."
    },
    {
      "key": "10.1074/jbc.M202029200_bib19",
      "doi-asserted-by": "crossref",
      "first-page": "327",
      "DOI": "10.1038/374327a0",
      "volume": "374",
      "author": "Shapiro",
      "year": "1995",
      "journal-title": "Nature."
    },
    {
      "key": "10.1074/jbc.M202029200_bib20",
      "doi-asserted-by": "crossref",
      "first-page": "1153",
      "DOI": "10.1016/S0896-6273(00)80496-1",
      "volume": "20",
      "author": "Tamura",
      "year": "1998",
      "journal-title": "Neuron."
    },
    {
      "key": "10.1074/jbc.M202029200_bib21",
      "doi-asserted-by": "crossref",
      "first-page": "1738",
      "DOI": "10.1093/emboj/18.7.1738",
      "volume": "18",
      "author": "Pertz",
      "year": "1999",
      "journal-title": "EMBO J."
    },
    {
      "key": "10.1074/jbc.M202029200_bib22",
      "doi-asserted-by": "crossref",
      "first-page": "405",
      "DOI": "10.1016/S0014-5793(97)01333-1",
      "volume": "417",
      "author": "Alattia",
      "year": "1997",
      "journal-title": "FEBS Lett."
    },
    {
      "key": "10.1074/jbc.M202029200_bib23",
      "doi-asserted-by": "crossref",
      "first-page": "7697",
      "DOI": "10.1021/bi9705624",
      "volume": "36",
      "author": "Koch",
      "year": "1997",
      "journal-title": "Biochemistry."
    },
    {
      "key": "10.1074/jbc.M202029200_bib24",
      "doi-asserted-by": "crossref",
      "first-page": "3507",
      "DOI": "10.1002/j.1460-2075.1996.tb00719.x",
      "volume": "15",
      "author": "Tomschy",
      "year": "1996",
      "journal-title": "EMBO J."
    },
    {
      "key": "10.1074/jbc.M202029200_bib25",
      "doi-asserted-by": "crossref",
      "first-page": "310",
      "DOI": "10.1038/7542",
      "volume": "6",
      "author": "Takeda",
      "year": "1999",
      "journal-title": "Nat. Struct. Biol."
    },
    {
      "key": "10.1074/jbc.M202029200_bib26",
      "doi-asserted-by": "crossref",
      "first-page": "4005",
      "DOI": "10.1073/pnas.070052697",
      "volume": "97",
      "author": "Baumgartner",
      "year": "2000",
      "journal-title": "Proc. Natl. Acad. Sci. U. S. A."
    },
    {
      "key": "10.1074/jbc.M202029200_bib27",
      "doi-asserted-by": "crossref",
      "first-page": "487",
      "DOI": "10.1083/jcb.135.2.487",
      "volume": "135",
      "author": "Brieher",
      "year": "1996",
      "journal-title": "J. Cell Biol."
    },
    {
      "key": "10.1074/jbc.M202029200_bib28",
      "doi-asserted-by": "crossref",
      "first-page": "308",
      "DOI": "10.1016/S0960-9822(06)00154-0",
      "volume": "7",
      "author": "Yap",
      "year": "1997",
      "journal-title": "Curr. Biol."
    },
    {
      "key": "10.1074/jbc.M202029200_bib29",
      "doi-asserted-by": "crossref",
      "first-page": "837",
      "DOI": "10.1083/jcb.142.3.837",
      "volume": "142",
      "author": "Chitaev",
      "year": "1998",
      "journal-title": "J. Cell Biol."
    },
    {
      "key": "10.1074/jbc.M202029200_bib30",
      "doi-asserted-by": "crossref",
      "first-page": "193",
      "DOI": "10.1016/0378-1119(91)90434-D",
      "volume": "108",
      "author": "Niwa",
      "year": "1991",
      "journal-title": "Gene (Amst.)."
    },
    {
      "key": "10.1074/jbc.M202029200_bib31",
      "doi-asserted-by": "crossref",
      "first-page": "1645",
      "DOI": "10.1083/jcb.111.4.1645",
      "volume": "111",
      "author": "Ozawa",
      "year": "1990",
      "journal-title": "J. Cell Biol."
    },
    {
      "key": "10.1074/jbc.M202029200_bib32",
      "doi-asserted-by": "crossref",
      "first-page": "579",
      "DOI": "10.1083/jcb.148.3.579",
      "volume": "148",
      "author": "Shan",
      "year": "2000",
      "journal-title": "J. Cell Biol."
    },
    {
      "key": "10.1074/jbc.M202029200_bib33",
      "doi-asserted-by": "crossref",
      "first-page": "569",
      "DOI": "10.1038/42408",
      "volume": "387",
      "author": "Simons",
      "year": "1997",
      "journal-title": "Nature."
    },
    {
      "key": "10.1074/jbc.M202029200_bib34",
      "doi-asserted-by": "crossref",
      "first-page": "1621",
      "DOI": "10.1242/jcs.112.10.1621",
      "volume": "112",
      "author": "Nieman",
      "year": "1999",
      "journal-title": "J. Cell Sci."
    },
    {
      "key": "10.1074/jbc.M202029200_bib35",
      "doi-asserted-by": "crossref",
      "first-page": "C404",
      "DOI": "10.1152/ajpcell.1999.276.2.C404",
      "volume": "276",
      "author": "Troxell",
      "year": "1999",
      "journal-title": "Am. J. Physiol."
    },
    {
      "key": "10.1074/jbc.M202029200_bib36",
      "doi-asserted-by": "crossref",
      "first-page": "30862",
      "DOI": "10.1074/jbc.M101712200",
      "volume": "276",
      "author": "Corps",
      "year": "2001",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "10.1074/jbc.M202029200_bib37",
      "doi-asserted-by": "crossref",
      "first-page": "17",
      "DOI": "10.1016/0014-5793(94)00467-6",
      "volume": "346",
      "author": "Lemmon",
      "year": "1994",
      "journal-title": "FEBS Lett."
    },
    {
      "key": "10.1074/jbc.M202029200_bib38",
      "doi-asserted-by": "crossref",
      "first-page": "4415",
      "DOI": "10.1242/jcs.112.23.4415",
      "volume": "112",
      "author": "Huber",
      "year": "1999",
      "journal-title": "J. Cell Sci."
    },
    {
      "key": "10.1074/jbc.M202029200_bib39",
      "doi-asserted-by": "crossref",
      "first-page": "231",
      "DOI": "10.1083/jcb.200103143",
      "volume": "154",
      "author": "Chappuis-Flament",
      "year": "2001",
      "journal-title": "J. Cell Biol."
    },
    {
      "key": "10.1074/jbc.M202029200_bib40",
      "doi-asserted-by": "crossref",
      "first-page": "345",
      "DOI": "10.1016/S0092-8674(00)81279-9",
      "volume": "84",
      "author": "Gumbiner",
      "year": "1996",
      "journal-title": "Cell."
    },
    {
      "key": "10.1074/jbc.M202029200_bib41",
      "doi-asserted-by": "crossref",
      "first-page": "11820",
      "DOI": "10.1073/pnas.96.21.11820",
      "volume": "96",
      "author": "Sivasankar",
      "year": "1999",
      "journal-title": "Proc. Natl. Acad. Sci. U. S. A."
    },
    {
      "key": "10.1074/jbc.M202029200_bib42",
      "doi-asserted-by": "crossref",
      "first-page": "3647",
      "DOI": "10.1002/j.1460-2075.1987.tb02697.x",
      "volume": "6",
      "author": "Ringwald",
      "year": "1987",
      "journal-title": "EMBO J."
    },
    {
      "key": "10.1074/jbc.M202029200_bib43",
      "doi-asserted-by": "crossref",
      "first-page": "5896",
      "DOI": "10.1093/nar/18.19.5896",
      "volume": "18",
      "author": "Reid",
      "year": "1990",
      "journal-title": "Nucleic Acids Res."
    },
    {
      "key": "10.1074/jbc.M202029200_bib44",
      "doi-asserted-by": "crossref",
      "first-page": "1548",
      "DOI": "10.1084/jem.166.5.1548",
      "volume": "166",
      "author": "Streuli",
      "year": "1987",
      "journal-title": "J. Exp. Med."
    }
  ],
  "container-title": "Journal of Biological Chemistry",
  "original-title": [],
  "language": "en",
  "link": [
    {
      "URL": "https://api.elsevier.com/content/article/PII:S0021925820850224?httpAccept=text/xml",
      "content-type": "text/xml",
      "content-version": "vor",
      "intended-application": "text-mining"
    },
    {
      "URL": "https://api.elsevier.com/content/article/PII:S0021925820850224?httpAccept=text/plain",
      "content-type": "text/plain",
      "content-version": "vor",
      "intended-application": "text-mining"
    },
    {
      "URL": "https://syndication.highwire.org/content/doi/10.1074/jbc.M202029200",
      "content-type": "unspecified",
      "content-version": "vor",
      "intended-application": "similarity-checking"
    }
  ],
  "deposited": {
    "date-parts": [
      [
        2022,
        1,
        5
      ]
    ],
    "date-time": "2022-01-05T21:35:22Z",
    "timestamp": 1641418522000
  },
  "score": 1,
  "resource": {
    "primary": {
      "URL": "https://linkinghub.elsevier.com/retrieve/pii/S0021925820850224"
    }
  },
  "subtitle": [],
  "short-title": [],
  "issued": {
    "date-parts": [
      [
        2002,
        5
      ]
    ]
  },
  "references-count": 44,
  "journal-issue": {
    "issue": "22",
    "published-print": {
      "date-parts": [
        [
          2002,
          5
        ]
      ]
    }
  },
  "alternative-id": [
    "S0021925820850224"
  ],
  "URL": "http://dx.doi.org/10.1074/jbc.M202029200",
  "relation": {},
  "ISSN": [
    "0021-9258"
  ],
  "subject": [],
  "container-title-short": "Journal of Biological Chemistry",
  "published": {
    "date-parts": [
      [
        2002,
        5
      ]
    ]
  }
}