DOI: 10.1074/jbc.270.6.2601. Mutational Analysis of the Double-stranded RNA (dsRNA) Binding Domain of the dsRNA-activated Protein Kinase, PKR

Mutational Analysis of the Double-stranded RNA (dsRNA) Binding Domain of the dsRNA-activated Protein Kinase, PKR

10.1074/jbc.270.6.2601

Crossref journal-article

Elsevier BV

Journal of Biological Chemistry (78)

Bibliography

McMillan, N. A. J., Carpick, B. W., Hollis, B., Toone, W. M., Zamanian-Daryoush, M., & Williams, B. R. G. (1995). Mutational Analysis of the Double-stranded RNA (dsRNA) Binding Domain of the dsRNA-activated Protein Kinase, PKR. Journal of Biological Chemistry, 270(6), 2601â2606.

Authors 6

Nigel A.J. McMillan (first)
Bruce W. Carpick (additional)
Britton Hollis (additional)
W. Mark Toone (additional)
Maryam Zamanian-Daryoush (additional)
Bryan R.G. Williams (additional)

References 38 Referenced 64

10.1089/jir.1989.9.641 / J. Interferon Res. by Hovanessian (1989)
10.1146/annurev.bi.51.070182.001343 / Annu. Rev. Biochem. by Lengyel (1982)
10.1016/0042-6822(91)90112-O / Virology by Samuel (1991)
10.1016/S0021-9258(18)47759-9 / J. Biol. Chem. by Galabru (1987)
10.1016/0092-8674(77)90330-0 / Cell by Farrel (1977)
10.1016/S0021-9258(19)30005-5 / J. Biol. Chem. by Hershey (1989)
10.1016/0092-8674(83)90326-4 / Cell by Safer (1983)
10.1073/pnas.91.14.6288 / Proc. Natl. Acad. Sci. U. S. A. by Kumar (1994)
10.1089/jir.1992.12.241 / J. Interferon Res. by Katze (1992)
10.1128/jvi.66.10.5805-5814.1992 / J. Virol. by Meurs (1992)
10.1073/pnas.90.1.232 / Proc. Natl. Acad. Sci. U. S. A. by Meurs (1993)
10.1126/science.1382315 / Science by Koromilas (1992)
10.1002/j.1460-2075.1992.tb05200.x / EMBO J. by Chong (1992)
10.1101/gad.6.12b.2478 / Genes & Dev. by Green (1992)
10.1073/pnas.89.12.5447 / Proc. Natl. Acad. Sci. U. S. A. by Feng (1992)
10.1016/S0021-9258(18)42567-7 / J. Biol. Chem. by Patel (1992)
{'key': '10.1074/jbc.270.6.2601_bib17', 'first-page': '5497', 'volume': '11', 'author': 'Katze', 'year': '1991', 'journal-title': 'Mol. Cell. Biol.'} / Mol. Cell. Biol. by Katze (1991)
10.1016/0042-6822(92)90733-6 / Virology by McCormack (1992)
10.1073/pnas.89.22.10979 / Proc. Natl. Acad. Sci. U. S. A. by St. Johnston (1992)
10.1006/viro.1994.1011 / Virology by McCormack (1994)
10.1016/0003-2697(92)90280-K / Anal. Biochem. by Deng (1992)
10.1016/0022-2836(82)90060-2 / J. Mol. Biol. by Busby (1982)
{'key': '10.1074/jbc.270.6.2601_bib23', 'series-title': 'Current Protocols in Molecular Biology', 'first-page': '13.13.4', 'author': 'Lundblad', 'year': '1994'} / Current Protocols in Molecular Biology by Lundblad (1994)
10.1084/jem.171.1.35 / J. Exp. Med. by Shakhov (1990)
10.1016/0092-8674(86)90760-9 / Cell by Kimura (1986)
10.1016/S0021-9258(17)32351-7 / J. Biol. Chem. by Patel (1994)
10.1073/pnas.90.10.4621 / Proc. Natl. Acad. Sci. U. S. A. by Barber (1993)
10.1073/pnas.90.10.4616 / Proc. Natl. Acad. Sci. U. S. A. by Dever (1993)
10.1126/science.7914032 / Science by Maran (1994)
10.1146/annurev.bi.47.070178.001343 / Annu. Rev. Biochem. by Chou (1978)
10.1073/pnas.89.11.4825 / Proc. Natl. Acad. Sci. U. S. A. by Chang (1992)
10.1073/pnas.89.22.10837 / Proc. Natl. Acad. Sci. U. S. A. by Thomis (1992)
10.1006/viro.1994.1601 / Virology by Maitra (1994)
10.1016/0092-8674(90)90374-N / Cell by Meurs (1990)
{'key': '10.1074/jbc.270.6.2601_bib35', 'first-page': '5433', 'volume': '10', 'author': 'Ahn', 'year': '1990', 'journal-title': 'Mol. Cell. Biol.'} / Mol. Cell. Biol. by Ahn (1990)
10.1093/nar/13.13.4677 / Nucleic Acids Res. by March (1985)
10.1016/0092-8674(91)90138-O / Cell by St. Johnston (1991)
10.1126/science.2011739 / Science by Gatignol (1991)

Dates

Type	When
Created	23 years, 1 month ago (July 26, 2002, 10:54 a.m.)
Deposited	1 year, 11 months ago (Sept. 30, 2023, 11:20 a.m.)
Indexed	3 months, 1 week ago (May 21, 2025, 4:06 a.m.)
Issued	30 years, 6 months ago (Feb. 1, 1995)
Published	30 years, 6 months ago (Feb. 1, 1995)
Published Print	30 years, 6 months ago (Feb. 1, 1995)

Funders 0

None

BibTeX

@article{McMillan_1995, title={Mutational Analysis of the Double-stranded RNA (dsRNA) Binding Domain of the dsRNA-activated Protein Kinase, PKR}, volume={270}, ISSN={0021-9258}, url={http://dx.doi.org/10.1074/jbc.270.6.2601}, DOI={10.1074/jbc.270.6.2601}, number={6}, journal={Journal of Biological Chemistry}, publisher={Elsevier BV}, author={McMillan, Nigel A.J. and Carpick, Bruce W. and Hollis, Britton and Toone, W. Mark and Zamanian-Daryoush, Maryam and Williams, Bryan R.G.}, year={1995}, month=feb, pages={2601–2606} }

JSON

{
  "indexed": {
    "date-parts": [
      [
        2025,
        5,
        21
      ]
    ],
    "date-time": "2025-05-21T08:06:24Z",
    "timestamp": 1747814784455
  },
  "reference-count": 38,
  "publisher": "Elsevier BV",
  "issue": "6",
  "license": [
    {
      "start": {
        "date-parts": [
          [
            1995,
            2,
            1
          ]
        ],
        "date-time": "1995-02-01T00:00:00Z",
        "timestamp": 791596800000
      },
      "content-version": "tdm",
      "delay-in-days": 0,
      "URL": "https://www.elsevier.com/tdm/userlicense/1.0/"
    },
    {
      "start": {
        "date-parts": [
          [
            2020,
            10,
            29
          ]
        ],
        "date-time": "2020-10-29T00:00:00Z",
        "timestamp": 1603929600000
      },
      "content-version": "vor",
      "delay-in-days": 9402,
      "URL": "http://creativecommons.org/licenses/by/4.0/"
    }
  ],
  "content-domain": {
    "domain": [
      "jbc.org",
      "elsevier.com",
      "sciencedirect.com"
    ],
    "crossmark-restriction": true
  },
  "published-print": {
    "date-parts": [
      [
        1995,
        2
      ]
    ]
  },
  "DOI": "10.1074/jbc.270.6.2601",
  "type": "journal-article",
  "created": {
    "date-parts": [
      [
        2002,
        7,
        26
      ]
    ],
    "date-time": "2002-07-26T14:54:25Z",
    "timestamp": 1027695265000
  },
  "page": "2601-2606",
  "update-policy": "http://dx.doi.org/10.1016/elsevier_cm_policy",
  "source": "Crossref",
  "is-referenced-by-count": 64,
  "title": "Mutational Analysis of the Double-stranded RNA (dsRNA) Binding Domain of the dsRNA-activated Protein Kinase, PKR",
  "prefix": "10.1016",
  "volume": "270",
  "author": [
    {
      "given": "Nigel A.J.",
      "family": "McMillan",
      "sequence": "first",
      "affiliation": []
    },
    {
      "given": "Bruce W.",
      "family": "Carpick",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "Britton",
      "family": "Hollis",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "W. Mark",
      "family": "Toone",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "Maryam",
      "family": "Zamanian-Daryoush",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "Bryan R.G.",
      "family": "Williams",
      "sequence": "additional",
      "affiliation": []
    }
  ],
  "member": "78",
  "reference": [
    {
      "key": "10.1074/jbc.270.6.2601_bib1",
      "doi-asserted-by": "crossref",
      "first-page": "641",
      "DOI": "10.1089/jir.1989.9.641",
      "volume": "9",
      "author": "Hovanessian",
      "year": "1989",
      "journal-title": "J. Interferon Res."
    },
    {
      "key": "10.1074/jbc.270.6.2601_bib2",
      "doi-asserted-by": "crossref",
      "first-page": "251",
      "DOI": "10.1146/annurev.bi.51.070182.001343",
      "volume": "51",
      "author": "Lengyel",
      "year": "1982",
      "journal-title": "Annu. Rev. Biochem."
    },
    {
      "key": "10.1074/jbc.270.6.2601_bib3",
      "doi-asserted-by": "crossref",
      "first-page": "1",
      "DOI": "10.1016/0042-6822(91)90112-O",
      "volume": "183",
      "author": "Samuel",
      "year": "1991",
      "journal-title": "Virology"
    },
    {
      "key": "10.1074/jbc.270.6.2601_bib4",
      "doi-asserted-by": "crossref",
      "first-page": "15538",
      "DOI": "10.1016/S0021-9258(18)47759-9",
      "volume": "262",
      "author": "Galabru",
      "year": "1987",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "10.1074/jbc.270.6.2601_bib5",
      "doi-asserted-by": "crossref",
      "first-page": "187",
      "DOI": "10.1016/0092-8674(77)90330-0",
      "volume": "11",
      "author": "Farrel",
      "year": "1977",
      "journal-title": "Cell"
    },
    {
      "key": "10.1074/jbc.270.6.2601_bib6",
      "doi-asserted-by": "crossref",
      "first-page": "20823",
      "DOI": "10.1016/S0021-9258(19)30005-5",
      "volume": "264",
      "author": "Hershey",
      "year": "1989",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "10.1074/jbc.270.6.2601_bib7",
      "doi-asserted-by": "crossref",
      "first-page": "7",
      "DOI": "10.1016/0092-8674(83)90326-4",
      "volume": "33",
      "author": "Safer",
      "year": "1983",
      "journal-title": "Cell"
    },
    {
      "key": "10.1074/jbc.270.6.2601_bib8",
      "doi-asserted-by": "crossref",
      "first-page": "6288",
      "DOI": "10.1073/pnas.91.14.6288",
      "volume": "91",
      "author": "Kumar",
      "year": "1994",
      "journal-title": "Proc. Natl. Acad. Sci. U. S. A."
    },
    {
      "key": "10.1074/jbc.270.6.2601_bib9",
      "doi-asserted-by": "crossref",
      "first-page": "241",
      "DOI": "10.1089/jir.1992.12.241",
      "volume": "12",
      "author": "Katze",
      "year": "1992",
      "journal-title": "J. Interferon Res."
    },
    {
      "key": "10.1074/jbc.270.6.2601_bib10",
      "doi-asserted-by": "crossref",
      "first-page": "5805",
      "DOI": "10.1128/jvi.66.10.5805-5814.1992",
      "volume": "66",
      "author": "Meurs",
      "year": "1992",
      "journal-title": "J. Virol."
    },
    {
      "key": "10.1074/jbc.270.6.2601_bib11",
      "doi-asserted-by": "crossref",
      "first-page": "232",
      "DOI": "10.1073/pnas.90.1.232",
      "volume": "90",
      "author": "Meurs",
      "year": "1993",
      "journal-title": "Proc. Natl. Acad. Sci. U. S. A."
    },
    {
      "key": "10.1074/jbc.270.6.2601_bib12",
      "doi-asserted-by": "crossref",
      "first-page": "1685",
      "DOI": "10.1126/science.1382315",
      "volume": "257",
      "author": "Koromilas",
      "year": "1992",
      "journal-title": "Science"
    },
    {
      "key": "10.1074/jbc.270.6.2601_bib13",
      "doi-asserted-by": "crossref",
      "first-page": "1553",
      "DOI": "10.1002/j.1460-2075.1992.tb05200.x",
      "volume": "11",
      "author": "Chong",
      "year": "1992",
      "journal-title": "EMBO J."
    },
    {
      "key": "10.1074/jbc.270.6.2601_bib14",
      "doi-asserted-by": "crossref",
      "first-page": "2478",
      "DOI": "10.1101/gad.6.12b.2478",
      "volume": "6",
      "author": "Green",
      "year": "1992",
      "journal-title": "Genes & Dev."
    },
    {
      "key": "10.1074/jbc.270.6.2601_bib15",
      "doi-asserted-by": "crossref",
      "first-page": "5447",
      "DOI": "10.1073/pnas.89.12.5447",
      "volume": "89",
      "author": "Feng",
      "year": "1992",
      "journal-title": "Proc. Natl. Acad. Sci. U. S. A."
    },
    {
      "key": "10.1074/jbc.270.6.2601_bib16",
      "doi-asserted-by": "crossref",
      "first-page": "7671",
      "DOI": "10.1016/S0021-9258(18)42567-7",
      "volume": "267",
      "author": "Patel",
      "year": "1992",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "10.1074/jbc.270.6.2601_bib17",
      "first-page": "5497",
      "volume": "11",
      "author": "Katze",
      "year": "1991",
      "journal-title": "Mol. Cell. Biol."
    },
    {
      "key": "10.1074/jbc.270.6.2601_bib18",
      "doi-asserted-by": "crossref",
      "first-page": "47",
      "DOI": "10.1016/0042-6822(92)90733-6",
      "volume": "188",
      "author": "McCormack",
      "year": "1992",
      "journal-title": "Virology"
    },
    {
      "key": "10.1074/jbc.270.6.2601_bib19",
      "doi-asserted-by": "crossref",
      "first-page": "10979",
      "DOI": "10.1073/pnas.89.22.10979",
      "volume": "89",
      "author": "St. Johnston",
      "year": "1992",
      "journal-title": "Proc. Natl. Acad. Sci. U. S. A."
    },
    {
      "key": "10.1074/jbc.270.6.2601_bib20",
      "doi-asserted-by": "crossref",
      "first-page": "92",
      "DOI": "10.1006/viro.1994.1011",
      "volume": "198",
      "author": "McCormack",
      "year": "1994",
      "journal-title": "Virology"
    },
    {
      "key": "10.1074/jbc.270.6.2601_bib21",
      "doi-asserted-by": "crossref",
      "first-page": "81",
      "DOI": "10.1016/0003-2697(92)90280-K",
      "volume": "200",
      "author": "Deng",
      "year": "1992",
      "journal-title": "Anal. Biochem."
    },
    {
      "key": "10.1074/jbc.270.6.2601_bib22",
      "doi-asserted-by": "crossref",
      "first-page": "197",
      "DOI": "10.1016/0022-2836(82)90060-2",
      "volume": "154",
      "author": "Busby",
      "year": "1982",
      "journal-title": "J. Mol. Biol."
    },
    {
      "key": "10.1074/jbc.270.6.2601_bib23",
      "series-title": "Current Protocols in Molecular Biology",
      "first-page": "13.13.4",
      "author": "Lundblad",
      "year": "1994"
    },
    {
      "key": "10.1074/jbc.270.6.2601_bib24",
      "doi-asserted-by": "crossref",
      "first-page": "35",
      "DOI": "10.1084/jem.171.1.35",
      "volume": "171",
      "author": "Shakhov",
      "year": "1990",
      "journal-title": "J. Exp. Med."
    },
    {
      "key": "10.1074/jbc.270.6.2601_bib25",
      "doi-asserted-by": "crossref",
      "first-page": "261",
      "DOI": "10.1016/0092-8674(86)90760-9",
      "volume": "44",
      "author": "Kimura",
      "year": "1986",
      "journal-title": "Cell"
    },
    {
      "key": "10.1074/jbc.270.6.2601_bib26",
      "doi-asserted-by": "crossref",
      "first-page": "18593",
      "DOI": "10.1016/S0021-9258(17)32351-7",
      "volume": "269",
      "author": "Patel",
      "year": "1994",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "10.1074/jbc.270.6.2601_bib27",
      "doi-asserted-by": "crossref",
      "first-page": "4621",
      "DOI": "10.1073/pnas.90.10.4621",
      "volume": "90",
      "author": "Barber",
      "year": "1993",
      "journal-title": "Proc. Natl. Acad. Sci. U. S. A."
    },
    {
      "key": "10.1074/jbc.270.6.2601_bib28",
      "doi-asserted-by": "crossref",
      "first-page": "4616",
      "DOI": "10.1073/pnas.90.10.4616",
      "volume": "90",
      "author": "Dever",
      "year": "1993",
      "journal-title": "Proc. Natl. Acad. Sci. U. S. A."
    },
    {
      "key": "10.1074/jbc.270.6.2601_bib29",
      "doi-asserted-by": "crossref",
      "first-page": "789",
      "DOI": "10.1126/science.7914032",
      "volume": "265",
      "author": "Maran",
      "year": "1994",
      "journal-title": "Science"
    },
    {
      "key": "10.1074/jbc.270.6.2601_bib30",
      "doi-asserted-by": "crossref",
      "first-page": "251",
      "DOI": "10.1146/annurev.bi.47.070178.001343",
      "volume": "47",
      "author": "Chou",
      "year": "1978",
      "journal-title": "Annu. Rev. Biochem."
    },
    {
      "key": "10.1074/jbc.270.6.2601_bib31",
      "doi-asserted-by": "crossref",
      "first-page": "4825",
      "DOI": "10.1073/pnas.89.11.4825",
      "volume": "89",
      "author": "Chang",
      "year": "1992",
      "journal-title": "Proc. Natl. Acad. Sci. U. S. A."
    },
    {
      "key": "10.1074/jbc.270.6.2601_bib32",
      "doi-asserted-by": "crossref",
      "first-page": "10837",
      "DOI": "10.1073/pnas.89.22.10837",
      "volume": "89",
      "author": "Thomis",
      "year": "1992",
      "journal-title": "Proc. Natl. Acad. Sci. U. S. A."
    },
    {
      "key": "10.1074/jbc.270.6.2601_bib33",
      "doi-asserted-by": "crossref",
      "first-page": "823",
      "DOI": "10.1006/viro.1994.1601",
      "volume": "204",
      "author": "Maitra",
      "year": "1994",
      "journal-title": "Virology"
    },
    {
      "key": "10.1074/jbc.270.6.2601_bib34",
      "doi-asserted-by": "crossref",
      "first-page": "379",
      "DOI": "10.1016/0092-8674(90)90374-N",
      "volume": "62",
      "author": "Meurs",
      "year": "1990",
      "journal-title": "Cell"
    },
    {
      "key": "10.1074/jbc.270.6.2601_bib35",
      "first-page": "5433",
      "volume": "10",
      "author": "Ahn",
      "year": "1990",
      "journal-title": "Mol. Cell. Biol."
    },
    {
      "key": "10.1074/jbc.270.6.2601_bib36",
      "doi-asserted-by": "crossref",
      "first-page": "4677",
      "DOI": "10.1093/nar/13.13.4677",
      "volume": "13",
      "author": "March",
      "year": "1985",
      "journal-title": "Nucleic Acids Res."
    },
    {
      "key": "10.1074/jbc.270.6.2601_bib37",
      "doi-asserted-by": "crossref",
      "first-page": "51",
      "DOI": "10.1016/0092-8674(91)90138-O",
      "volume": "66",
      "author": "St. Johnston",
      "year": "1991",
      "journal-title": "Cell"
    },
    {
      "key": "10.1074/jbc.270.6.2601_bib38",
      "doi-asserted-by": "crossref",
      "first-page": "1597",
      "DOI": "10.1126/science.2011739",
      "volume": "251",
      "author": "Gatignol",
      "year": "1991",
      "journal-title": "Science"
    }
  ],
  "container-title": "Journal of Biological Chemistry",
  "original-title": [],
  "language": "en",
  "link": [
    {
      "URL": "https://api.elsevier.com/content/article/PII:S0021925817307056?httpAccept=text/xml",
      "content-type": "text/xml",
      "content-version": "vor",
      "intended-application": "text-mining"
    },
    {
      "URL": "https://api.elsevier.com/content/article/PII:S0021925817307056?httpAccept=text/plain",
      "content-type": "text/plain",
      "content-version": "vor",
      "intended-application": "text-mining"
    },
    {
      "URL": "https://syndication.highwire.org/content/doi/10.1074/jbc.270.6.2601",
      "content-type": "unspecified",
      "content-version": "vor",
      "intended-application": "similarity-checking"
    }
  ],
  "deposited": {
    "date-parts": [
      [
        2023,
        9,
        30
      ]
    ],
    "date-time": "2023-09-30T15:20:18Z",
    "timestamp": 1696087218000
  },
  "score": 1,
  "resource": {
    "primary": {
      "URL": "https://linkinghub.elsevier.com/retrieve/pii/S0021925817307056"
    }
  },
  "subtitle": [],
  "short-title": [],
  "issued": {
    "date-parts": [
      [
        1995,
        2
      ]
    ]
  },
  "references-count": 38,
  "journal-issue": {
    "issue": "6",
    "published-print": {
      "date-parts": [
        [
          1995,
          2
        ]
      ]
    }
  },
  "alternative-id": [
    "S0021925817307056"
  ],
  "URL": "http://dx.doi.org/10.1074/jbc.270.6.2601",
  "relation": {},
  "ISSN": [
    "0021-9258"
  ],
  "subject": [],
  "container-title-short": "Journal of Biological Chemistry",
  "published": {
    "date-parts": [
      [
        1995,
        2
      ]
    ]
  },
  "assertion": [
    {
      "value": "Elsevier",
      "name": "publisher",
      "label": "This article is maintained by"
    },
    {
      "value": "Mutational Analysis of the Double-stranded RNA (dsRNA) Binding Domain of the dsRNA-activated Protein Kinase, PKR",
      "name": "articletitle",
      "label": "Article Title"
    },
    {
      "value": "Journal of Biological Chemistry",
      "name": "journaltitle",
      "label": "Journal Title"
    },
    {
      "value": "https://doi.org/10.1074/jbc.270.6.2601",
      "name": "articlelink",
      "label": "CrossRef DOI link to publisher maintained version"
    },
    {
      "value": "article",
      "name": "content_type",
      "label": "Content Type"
    },
    {
      "value": "\u00a9 1995 ASBMB. Currently published by Elsevier Inc; originally published by American Society for Biochemistry and Molecular Biology.",
      "name": "copyright",
      "label": "Copyright"
    }
  ]
}