DOI: 10.1073/pnas.93.25.14654. Yeast homologues of higher eukaryotic TFIID subunits

Yeast homologues of higher eukaryotic TFIID subunits

10.1073/pnas.93.25.14654

Crossref journal-article

Proceedings of the National Academy of Sciences

Proceedings of the National Academy of Sciences (341)

Abstract

In eukaryotic cells the TATA-binding protein (TBP) associates with other proteins known as TBP-associated factors (TAFs) to form multisubunit transcription factors important for gene expression by all three nuclear RNA polymerases. Computer searching of the complete Saccharomyces cerevisiae genome revealed five previously unidentified yeast genes with significant sequence similarity to known human and Drosophila RNA polymerase II TAFs. Each of these genes is essential for viability. A sixth essential gene ( FUN81 ) has previously been noted to be similar to human TAF II 18. Coimmunoprecipitation experiments show that all six proteins are associated with TBP, demonstrating that they are true TAFs. Furthermore, these proteins are present in complexes containing the TAF II 130 subunit, indicating that they are components of TFIID. Based on their predicted molecular weights, these genes have been designated TAF67 , TAF61(68) , TAF40 , TAF23(25) , TAF19 ( FUN81 ), and TAF17 . Yeast TAF61 is significantly larger than its higher eukaryotic homologues, and deletion analysis demonstrates that the evolutionarily conserved, histone-like domain is sufficient and necessary to support viability.

Bibliography

Moqtaderi, Z., Yale, J. D., Struhl, K., & Buratowski, S. (1996). Yeast homologues of higher eukaryoticâTFIIDâsubunits. Proceedings of the National Academy of Sciences, 93(25), 14654â14658.

Authors 4

Zarmik Moqtaderi (first)
Jacqueline DePaulo Yale (additional)
Kevin Struhl (additional)
Stephen Buratowski (additional)

References 41 Referenced 73

10.1101/gad.7.7b.1291
10.1146/annurev.bi.65.070196.004005
10.1073/pnas.89.17.8140
10.1016/S0021-9258(17)31630-7
10.1016/0955-0674(94)90033-7
10.1016/0092-8674(94)90403-0
10.1038/371523a0
10.1073/pnas.92.18.8224
10.1074/jbc.271.23.13706
10.1038/383188a0
10.1038/383185a0
10.1101/gad.10.18.2368
10.1126/science.8303298
10.1101/gad.5.11.1935
10.1016/0092-8674(89)90515-1
10.1038/341299a0
10.1073/pnas.86.20.7785
10.1073/pnas.86.24.9803
10.1016/0378-1119(87)90286-1
10.1002/j.1460-2075.1995.tb07138.x
10.1126/science.272.5261.481
10.1016/S0022-2836(05)80360-2
F M Ausubel, R Brent, R E Kingston, D D Moore, J G Seidman, J A Smith, K Struhl Current Protocols in Molecular Biology (Wiley, New York, 1991). / Current Protocols in Molecular Biology by Ausubel F M (1991)
C Guthrie, G R Fink Methods Enzymol 194, 1–933 (1991). / Methods Enzymol by Guthrie C (1991)
10.1016/0092-8674(84)90412-4
10.1016/0076-6879(87)54076-9
10.1016/S0021-9258(18)50101-0
E Harlow, D Lane Antibodies: A Laboratory Manual (Cold Spring Harbor Lab. Press, Plainview, NY, 1988). / Antibodies: A Laboratory Manual by Harlow E (1988)
10.1016/0092-8674(93)90664-C
10.1073/pnas.90.13.5896
10.1126/science.7824954
10.1074/jbc.271.33.19774
10.1002/j.1460-2075.1996.tb00672.x
10.1101/gad.7.12b.2587
10.1016/0092-8674(94)90404-9
10.1074/jbc.271.30.18194
10.1016/0092-8674(90)90668-5
10.1002/j.1460-2075.1996.tb00740.x
10.1101/gad.6.7.1319
10.1128/MCB.15.2.983
10.1038/380356a0

Dates

Type	When
Created	23 years ago (July 26, 2002, 10:35 a.m.)
Deposited	3 years, 4 months ago (April 13, 2022, 2:24 p.m.)
Indexed	11 months, 3 weeks ago (Sept. 3, 2024, 11:44 a.m.)
Issued	28 years, 8 months ago (Dec. 10, 1996)
Published	28 years, 8 months ago (Dec. 10, 1996)
Published Online	28 years, 8 months ago (Dec. 10, 1996)
Published Print	28 years, 8 months ago (Dec. 10, 1996)

Funders 0

None

BibTeX

@article{Moqtaderi_1996, title={Yeast homologues of higher eukaryotic TFIID subunits}, volume={93}, ISSN={1091-6490}, url={http://dx.doi.org/10.1073/pnas.93.25.14654}, DOI={10.1073/pnas.93.25.14654}, number={25}, journal={Proceedings of the National Academy of Sciences}, publisher={Proceedings of the National Academy of Sciences}, author={Moqtaderi, Zarmik and Yale, Jacqueline DePaulo and Struhl, Kevin and Buratowski, Stephen}, year={1996}, month=dec, pages={14654–14658} }

JSON

{
  "indexed": {
    "date-parts": [
      [
        2024,
        9,
        3
      ]
    ],
    "date-time": "2024-09-03T15:44:38Z",
    "timestamp": 1725378278586
  },
  "reference-count": 41,
  "publisher": "Proceedings of the National Academy of Sciences",
  "issue": "25",
  "content-domain": {
    "domain": [
      "www.pnas.org"
    ],
    "crossmark-restriction": true
  },
  "published-print": {
    "date-parts": [
      [
        1996,
        12,
        10
      ]
    ]
  },
  "abstract": "<jats:p>\n            In eukaryotic cells the TATA-binding protein (TBP) associates with\n other proteins known as TBP-associated factors (TAFs) to form\n multisubunit transcription factors important for gene expression by all\n three nuclear RNA polymerases. Computer searching of the complete\n            <jats:italic>Saccharomyces cerevisiae</jats:italic>\n            genome revealed five previously\n unidentified yeast genes with significant sequence similarity to known\n human and\n            <jats:italic>Drosophila</jats:italic>\n            RNA polymerase II TAFs. Each of\n these genes is essential for viability. A sixth essential gene\n (\n            <jats:italic>FUN81</jats:italic>\n            ) has previously been noted to be similar to human\n TAF\n            <jats:sub>II</jats:sub>\n            18. Coimmunoprecipitation experiments show that all\n six proteins are associated with TBP, demonstrating that they are true\n TAFs. Furthermore, these proteins are present in complexes containing\n the TAF\n            <jats:sub>II</jats:sub>\n            130 subunit, indicating that they are components\n of TFIID. Based on their predicted molecular weights, these genes have\n been designated\n            <jats:italic>TAF67</jats:italic>\n            ,\n            <jats:italic>TAF61(68)</jats:italic>\n            ,\n            <jats:italic>TAF40</jats:italic>\n            ,\n            <jats:italic>TAF23(25)</jats:italic>\n            ,\n            <jats:italic>TAF19</jats:italic>\n            (\n            <jats:italic>FUN81</jats:italic>\n            ), and\n            <jats:italic>TAF17</jats:italic>\n            .\n Yeast TAF61 is significantly larger than its higher eukaryotic\n homologues, and deletion analysis demonstrates that the evolutionarily\n conserved, histone-like domain is sufficient and necessary to support\n viability.\n          </jats:p>",
  "DOI": "10.1073/pnas.93.25.14654",
  "type": "journal-article",
  "created": {
    "date-parts": [
      [
        2002,
        7,
        26
      ]
    ],
    "date-time": "2002-07-26T14:35:50Z",
    "timestamp": 1027694150000
  },
  "page": "14654-14658",
  "update-policy": "http://dx.doi.org/10.1073/pnas.cm10313",
  "source": "Crossref",
  "is-referenced-by-count": 73,
  "title": "Yeast homologues of higher eukaryotic\u2009TFIID\u2009subunits",
  "prefix": "10.1073",
  "volume": "93",
  "author": [
    {
      "given": "Zarmik",
      "family": "Moqtaderi",
      "sequence": "first",
      "affiliation": [
        {
          "name": "Department of Biological Chemistry and Molecular Pharmacology,\r Harvard Medical School, 240 Longwood Avenue, Boston, MA 02115"
        }
      ]
    },
    {
      "given": "Jacqueline\u2009DePaulo",
      "family": "Yale",
      "sequence": "additional",
      "affiliation": [
        {
          "name": "Department of Biological Chemistry and Molecular Pharmacology,\r Harvard Medical School, 240 Longwood Avenue, Boston, MA 02115"
        }
      ]
    },
    {
      "given": "Kevin",
      "family": "Struhl",
      "sequence": "additional",
      "affiliation": [
        {
          "name": "Department of Biological Chemistry and Molecular Pharmacology,\r Harvard Medical School, 240 Longwood Avenue, Boston, MA 02115"
        }
      ]
    },
    {
      "given": "Stephen",
      "family": "Buratowski",
      "sequence": "additional",
      "affiliation": [
        {
          "name": "Department of Biological Chemistry and Molecular Pharmacology,\r Harvard Medical School, 240 Longwood Avenue, Boston, MA 02115"
        }
      ]
    }
  ],
  "member": "341",
  "published-online": {
    "date-parts": [
      [
        1996,
        12,
        10
      ]
    ]
  },
  "reference": [
    {
      "key": "e_1_3_2_1_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1101/gad.7.7b.1291"
    },
    {
      "key": "e_1_3_2_2_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1146/annurev.bi.65.070196.004005"
    },
    {
      "key": "e_1_3_2_3_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1073/pnas.89.17.8140"
    },
    {
      "key": "e_1_3_2_4_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/S0021-9258(17)31630-7"
    },
    {
      "key": "e_1_3_2_5_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/0955-0674(94)90033-7"
    },
    {
      "key": "e_1_3_2_6_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/0092-8674(94)90403-0"
    },
    {
      "key": "e_1_3_2_7_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1038/371523a0"
    },
    {
      "key": "e_1_3_2_8_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1073/pnas.92.18.8224"
    },
    {
      "key": "e_1_3_2_9_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1074/jbc.271.23.13706"
    },
    {
      "key": "e_1_3_2_10_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1038/383188a0"
    },
    {
      "key": "e_1_3_2_11_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1038/383185a0"
    },
    {
      "key": "e_1_3_2_12_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1101/gad.10.18.2368"
    },
    {
      "key": "e_1_3_2_13_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1126/science.8303298"
    },
    {
      "key": "e_1_3_2_14_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1101/gad.5.11.1935"
    },
    {
      "key": "e_1_3_2_15_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/0092-8674(89)90515-1"
    },
    {
      "key": "e_1_3_2_16_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1038/341299a0"
    },
    {
      "key": "e_1_3_2_17_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1073/pnas.86.20.7785"
    },
    {
      "key": "e_1_3_2_18_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1073/pnas.86.24.9803"
    },
    {
      "key": "e_1_3_2_19_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/0378-1119(87)90286-1"
    },
    {
      "key": "e_1_3_2_20_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1002/j.1460-2075.1995.tb07138.x"
    },
    {
      "key": "e_1_3_2_21_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1126/science.272.5261.481"
    },
    {
      "key": "e_1_3_2_22_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/S0022-2836(05)80360-2"
    },
    {
      "key": "e_1_3_2_23_2",
      "volume-title": "Current Protocols in Molecular Biology",
      "author": "Ausubel F M",
      "year": "1991",
      "unstructured": "F M Ausubel, R Brent, R E Kingston, D D Moore, J G Seidman, J A Smith, K Struhl Current Protocols in Molecular Biology (Wiley, New York, 1991)."
    },
    {
      "key": "e_1_3_2_24_2",
      "first-page": "1",
      "volume": "194",
      "author": "Guthrie C",
      "year": "1991",
      "unstructured": "C Guthrie, G R Fink Methods Enzymol 194, 1\u2013933 (1991).",
      "journal-title": "Methods Enzymol"
    },
    {
      "key": "e_1_3_2_25_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/0092-8674(84)90412-4"
    },
    {
      "key": "e_1_3_2_26_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/0076-6879(87)54076-9"
    },
    {
      "key": "e_1_3_2_27_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/S0021-9258(18)50101-0"
    },
    {
      "key": "e_1_3_2_28_2",
      "volume-title": "Antibodies: A Laboratory Manual",
      "author": "Harlow E",
      "year": "1988",
      "unstructured": "E Harlow, D Lane Antibodies: A Laboratory Manual (Cold Spring Harbor Lab. Press, Plainview, NY, 1988)."
    },
    {
      "key": "e_1_3_2_29_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/0092-8674(93)90664-C"
    },
    {
      "key": "e_1_3_2_30_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1073/pnas.90.13.5896"
    },
    {
      "key": "e_1_3_2_31_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1126/science.7824954"
    },
    {
      "key": "e_1_3_2_32_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1074/jbc.271.33.19774"
    },
    {
      "key": "e_1_3_2_33_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1002/j.1460-2075.1996.tb00672.x"
    },
    {
      "key": "e_1_3_2_34_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1101/gad.7.12b.2587"
    },
    {
      "key": "e_1_3_2_35_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/0092-8674(94)90404-9"
    },
    {
      "key": "e_1_3_2_36_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1074/jbc.271.30.18194"
    },
    {
      "key": "e_1_3_2_37_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/0092-8674(90)90668-5"
    },
    {
      "key": "e_1_3_2_38_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1002/j.1460-2075.1996.tb00740.x"
    },
    {
      "key": "e_1_3_2_39_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1101/gad.6.7.1319"
    },
    {
      "key": "e_1_3_2_40_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1128/MCB.15.2.983"
    },
    {
      "key": "e_1_3_2_41_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1038/380356a0"
    }
  ],
  "container-title": "Proceedings of the National Academy of Sciences",
  "original-title": [],
  "language": "en",
  "link": [
    {
      "URL": "https://pnas.org/doi/pdf/10.1073/pnas.93.25.14654",
      "content-type": "unspecified",
      "content-version": "vor",
      "intended-application": "similarity-checking"
    }
  ],
  "deposited": {
    "date-parts": [
      [
        2022,
        4,
        13
      ]
    ],
    "date-time": "2022-04-13T18:24:20Z",
    "timestamp": 1649874260000
  },
  "score": 1,
  "resource": {
    "primary": {
      "URL": "https://pnas.org/doi/full/10.1073/pnas.93.25.14654"
    }
  },
  "subtitle": [],
  "short-title": [],
  "issued": {
    "date-parts": [
      [
        1996,
        12,
        10
      ]
    ]
  },
  "references-count": 41,
  "journal-issue": {
    "issue": "25",
    "published-print": {
      "date-parts": [
        [
          1996,
          12,
          10
        ]
      ]
    }
  },
  "alternative-id": [
    "10.1073/pnas.93.25.14654"
  ],
  "URL": "http://dx.doi.org/10.1073/pnas.93.25.14654",
  "relation": {},
  "ISSN": [
    "0027-8424",
    "1091-6490"
  ],
  "subject": [],
  "container-title-short": "Proc. Natl. Acad. Sci. U.S.A.",
  "published": {
    "date-parts": [
      [
        1996,
        12,
        10
      ]
    ]
  },
  "assertion": [
    {
      "value": "1996-09-05",
      "order": 0,
      "name": "received",
      "label": "Received",
      "group": {
        "name": "publication_history",
        "label": "Publication History"
      }
    },
    {
      "value": "1996-10-11",
      "order": 1,
      "name": "accepted",
      "label": "Accepted",
      "group": {
        "name": "publication_history",
        "label": "Publication History"
      }
    },
    {
      "value": "1996-12-10",
      "order": 2,
      "name": "published",
      "label": "Published",
      "group": {
        "name": "publication_history",
        "label": "Publication History"
      }
    }
  ]
}