DOI: 10.1073/pnas.93.10.4862. Crystal structure of a human TATA box-binding protein/TATA element complex.

Crystal structure of a human TATA box-binding protein/TATA element complex.

10.1073/pnas.93.10.4862

Crossref journal-article

Proceedings of the National Academy of Sciences

Proceedings of the National Academy of Sciences (341)

Abstract

The TATA box-binding protein (TBP) is required by all three eukaryotic RNA polymerases for correct initiation of transcription of ribosomal, messenger, small nuclear, and transfer RNAs. The cocrystal structure of the C-terminal/core region of human TBP complexed with the TATA element of the adenovirus major late promoter has been determined at 1.9 angstroms resolution. Structural and functional analyses of the protein-DNA complex are presented, with a detailed comparison to our 1.9-angstroms resolution structure of Arabidopsis thaliana TBP2 bound to the same TATA box.

Bibliography

Nikolov, D. B., Chen, H., Halay, E. D., Hoffman, A., Roeder, R. G., & Burley, S. K. (1996). Crystal structure of a human TATA box-binding protein/TATA element complex. Proceedings of the National Academy of Sciences, 93(10), 4862â4867.

Authors 6

D B Nikolov (first)
H Chen (additional)
E D Halay (additional)
A Hoffman (additional)
R G Roeder (additional)
S K Burley (additional)

References 0 Referenced 231

None

Dates

Type	When
Created	23 years ago (July 26, 2002, 10:43 a.m.)
Deposited	3 years, 4 months ago (April 13, 2022, 2:09 p.m.)
Indexed	1 month, 2 weeks ago (July 7, 2025, 6:25 a.m.)
Issued	29 years, 3 months ago (May 14, 1996)
Published	29 years, 3 months ago (May 14, 1996)
Published Online	29 years, 3 months ago (May 14, 1996)
Published Print	29 years, 3 months ago (May 14, 1996)

Funders 0

None

BibTeX

@article{Nikolov_1996, title={Crystal structure of a human TATA box-binding protein/TATA element complex.}, volume={93}, ISSN={1091-6490}, url={http://dx.doi.org/10.1073/pnas.93.10.4862}, DOI={10.1073/pnas.93.10.4862}, number={10}, journal={Proceedings of the National Academy of Sciences}, publisher={Proceedings of the National Academy of Sciences}, author={Nikolov, D B and Chen, H and Halay, E D and Hoffman, A and Roeder, R G and Burley, S K}, year={1996}, month=may, pages={4862–4867} }

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