DOI: 10.1073/pnas.93.1.13. Principles of protein-protein interactions.

Principles of protein-protein interactions.

10.1073/pnas.93.1.13

Crossref journal-article

Proceedings of the National Academy of Sciences

Proceedings of the National Academy of Sciences (341)

Abstract

This review examines protein complexes in the Brookhaven Protein Databank to gain a better understanding of the principles governing the interactions involved in protein-protein recognition. The factors that influence the formation of protein-protein complexes are explored in four different types of protein-protein complexes--homodimeric proteins, heterodimeric proteins, enzyme-inhibitor complexes, and antibody-protein complexes. The comparison between the complexes highlights differences that reflect their biological roles.

Bibliography

Jones, S., & Thornton, J. M. (1996). Principles of protein-protein interactions. Proceedings of the National Academy of Sciences, 93(1), 13â20.

Authors 2

S Jones (first)
J M Thornton (additional)

References 0 Referenced 2,217

None

Dates

Type	When
Created	23 years, 1 month ago (July 26, 2002, 10:32 a.m.)
Deposited	3 years, 4 months ago (April 13, 2022, 2:11 p.m.)
Indexed	1 day, 16 hours ago (Aug. 28, 2025, 8:43 a.m.)
Issued	29 years, 7 months ago (Jan. 9, 1996)
Published	29 years, 7 months ago (Jan. 9, 1996)
Published Online	29 years, 7 months ago (Jan. 9, 1996)
Published Print	29 years, 7 months ago (Jan. 9, 1996)

Funders 0

None

BibTeX

@article{Jones_1996, title={Principles of protein-protein interactions.}, volume={93}, ISSN={1091-6490}, url={http://dx.doi.org/10.1073/pnas.93.1.13}, DOI={10.1073/pnas.93.1.13}, number={1}, journal={Proceedings of the National Academy of Sciences}, publisher={Proceedings of the National Academy of Sciences}, author={Jones, S and Thornton, J M}, year={1996}, month=jan, pages={13–20} }

JSON

{
  "indexed": {
    "date-parts": [
      [
        2025,
        8,
        28
      ]
    ],
    "date-time": "2025-08-28T12:43:59Z",
    "timestamp": 1756385039332
  },
  "reference-count": 0,
  "publisher": "Proceedings of the National Academy of Sciences",
  "issue": "1",
  "content-domain": {
    "domain": [
      "www.pnas.org"
    ],
    "crossmark-restriction": true
  },
  "published-print": {
    "date-parts": [
      [
        1996,
        1,
        9
      ]
    ]
  },
  "abstract": "<jats:p>This review examines protein complexes in the Brookhaven Protein Databank to gain a better understanding of the principles governing the interactions involved in protein-protein recognition. The factors that influence the formation of protein-protein complexes are explored in four different types of protein-protein complexes--homodimeric proteins, heterodimeric proteins, enzyme-inhibitor complexes, and antibody-protein complexes. The comparison between the complexes highlights differences that reflect their biological roles.</jats:p>",
  "DOI": "10.1073/pnas.93.1.13",
  "type": "journal-article",
  "created": {
    "date-parts": [
      [
        2002,
        7,
        26
      ]
    ],
    "date-time": "2002-07-26T14:32:33Z",
    "timestamp": 1027693953000
  },
  "page": "13-20",
  "update-policy": "http://dx.doi.org/10.1073/pnas.cm10313",
  "source": "Crossref",
  "is-referenced-by-count": 2217,
  "title": "Principles of protein-protein interactions.",
  "prefix": "10.1073",
  "volume": "93",
  "author": [
    {
      "given": "S",
      "family": "Jones",
      "sequence": "first",
      "affiliation": [
        {
          "name": "Department of Biochemistry and Molecular Biology, University College, London, England."
        }
      ]
    },
    {
      "given": "J M",
      "family": "Thornton",
      "sequence": "additional",
      "affiliation": [
        {
          "name": "Department of Biochemistry and Molecular Biology, University College, London, England."
        }
      ]
    }
  ],
  "member": "341",
  "published-online": {
    "date-parts": [
      [
        1996,
        1,
        9
      ]
    ]
  },
  "container-title": "Proceedings of the National Academy of Sciences",
  "original-title": [],
  "language": "en",
  "link": [
    {
      "URL": "https://pnas.org/doi/pdf/10.1073/pnas.93.1.13",
      "content-type": "unspecified",
      "content-version": "vor",
      "intended-application": "similarity-checking"
    }
  ],
  "deposited": {
    "date-parts": [
      [
        2022,
        4,
        13
      ]
    ],
    "date-time": "2022-04-13T18:11:04Z",
    "timestamp": 1649873464000
  },
  "score": 1,
  "resource": {
    "primary": {
      "URL": "https://pnas.org/doi/full/10.1073/pnas.93.1.13"
    }
  },
  "subtitle": [],
  "short-title": [],
  "issued": {
    "date-parts": [
      [
        1996,
        1,
        9
      ]
    ]
  },
  "references-count": 0,
  "journal-issue": {
    "issue": "1",
    "published-print": {
      "date-parts": [
        [
          1996,
          1,
          9
        ]
      ]
    }
  },
  "alternative-id": [
    "10.1073/pnas.93.1.13"
  ],
  "URL": "http://dx.doi.org/10.1073/pnas.93.1.13",
  "relation": {},
  "ISSN": [
    "0027-8424",
    "1091-6490"
  ],
  "subject": [],
  "container-title-short": "Proc. Natl. Acad. Sci. U.S.A.",
  "published": {
    "date-parts": [
      [
        1996,
        1,
        9
      ]
    ]
  },
  "assertion": [
    {
      "value": "1996-01-09",
      "order": 2,
      "name": "published",
      "label": "Published",
      "group": {
        "name": "publication_history",
        "label": "Publication History"
      }
    }
  ]
}