DOI: 10.1073/pnas.92.24.11317. Inferring phylogenies from DNA sequences of unequal base compositions.

Inferring phylogenies from DNA sequences of unequal base compositions.

10.1073/pnas.92.24.11317

Crossref journal-article

Proceedings of the National Academy of Sciences

Proceedings of the National Academy of Sciences (341)

Abstract

A new method for computing evolutionary distances between DNA sequences is proposed. Contrasting with classical methods, the underlying model does not assume that sequence base compositions (A, C, G, and T contents) are at equilibrium, thus allowing unequal base compositions among compared sequences. This makes the method more efficient than the usual ones in recovering phylogenetic trees from sequence data when base composition is heterogeneous within the data set, as we show by using both simulated and empirical data. When applied to small-subunit ribosomal RNA sequences from several prokaryotic or eukaryotic organisms, this method provides evidence for an early divergence of the microsporidian Vairimorpha necatrix in the eukaryotic lineage.

Bibliography

Galtier, N., & Gouy, M. (1995). Inferring phylogenies from DNA sequences of unequal base compositions. Proceedings of the National Academy of Sciences, 92(24), 11317â11321.

Authors 2

N Galtier (first)
M Gouy (additional)

References 0 Referenced 182

None

Dates

Type	When
Created	19 years, 2 months ago (May 31, 2006, 9:24 a.m.)
Deposited	3 years, 4 months ago (April 13, 2022, 1:50 p.m.)
Indexed	3 weeks, 4 days ago (Aug. 5, 2025, 8:47 a.m.)
Issued	29 years, 9 months ago (Nov. 21, 1995)
Published	29 years, 9 months ago (Nov. 21, 1995)
Published Online	29 years, 9 months ago (Nov. 21, 1995)
Published Print	29 years, 9 months ago (Nov. 21, 1995)

Funders 0

None

BibTeX

@article{Galtier_1995, title={Inferring phylogenies from DNA sequences of unequal base compositions.}, volume={92}, ISSN={1091-6490}, url={http://dx.doi.org/10.1073/pnas.92.24.11317}, DOI={10.1073/pnas.92.24.11317}, number={24}, journal={Proceedings of the National Academy of Sciences}, publisher={Proceedings of the National Academy of Sciences}, author={Galtier, N and Gouy, M}, year={1995}, month=nov, pages={11317–11321} }

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