DOI: 10.1073/pnas.91.22.10502. Posttranscriptional silencing of reporter transgenes in tobacco correlates with DNA methylation.

Posttranscriptional silencing of reporter transgenes in tobacco correlates with DNA methylation.

10.1073/pnas.91.22.10502

Crossref journal-article

Proceedings of the National Academy of Sciences

Proceedings of the National Academy of Sciences (341)

Abstract

Endogenous plant genes or transgenes can be silenced on introduction of homologous gene sequences. Here we document a reporter gene-silencing event in Nicotiana tabacum that has a distinctive combination of features--i.e., (i) silencing occurs by a posttranscriptional process, (ii) silencing correlates with DNA methylation, and (iii) this de novo methylation is not restricted to cytosines located in the symmetrical motifs CG and CXG.

Bibliography

Ingelbrecht, I., Van Houdt, H., Van Montagu, M., & Depicker, A. (1994). Posttranscriptional silencing of reporter transgenes in tobacco correlates with DNA methylation. Proceedings of the National Academy of Sciences, 91(22), 10502â10506.

Authors 4

I Ingelbrecht (first)
H Van Houdt (additional)
M Van Montagu (additional)
A Depicker (additional)

References 0 Referenced 184

None

Dates

Type	When
Created	19 years, 3 months ago (May 31, 2006, 8:58 a.m.)
Deposited	3 years, 4 months ago (April 13, 2022, 2:04 p.m.)
Indexed	4 weeks ago (Aug. 5, 2025, 8:55 a.m.)
Issued	30 years, 10 months ago (Oct. 25, 1994)
Published	30 years, 10 months ago (Oct. 25, 1994)
Published Online	30 years, 10 months ago (Oct. 25, 1994)
Published Print	30 years, 10 months ago (Oct. 25, 1994)

Funders 0

None

BibTeX

@article{Ingelbrecht_1994, title={Posttranscriptional silencing of reporter transgenes in tobacco correlates with DNA methylation.}, volume={91}, ISSN={1091-6490}, url={http://dx.doi.org/10.1073/pnas.91.22.10502}, DOI={10.1073/pnas.91.22.10502}, number={22}, journal={Proceedings of the National Academy of Sciences}, publisher={Proceedings of the National Academy of Sciences}, author={Ingelbrecht, I and Van Houdt, H and Van Montagu, M and Depicker, A}, year={1994}, month=oct, pages={10502–10506} }

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