DOI: 10.1073/pnas.89.21.10512. TFC3: gene encoding the B-block binding subunit of the yeast transcription factor IIIC.

TFC3: gene encoding the B-block binding subunit of the yeast transcription factor IIIC.

10.1073/pnas.89.21.10512

Crossref journal-article

Proceedings of the National Academy of Sciences

Proceedings of the National Academy of Sciences (341)

Abstract

Yeast transcription factor IIIC (TFIIIC) is a multisubunit protein complex that interacts with two control elements of class III promoters called the A and B blocks. Here we describe the gene encoding the 138-kDa subunit (tau 138), which is involved in B-block binding. From the DNA sequence, the open reading frame, interrupted by an intron with an unusual 3' splice acceptor site, is in agreement with all the microsequencing data for peptides within tau 138. TFC3 is a single-copy gene located on chromosome I; it is essential for cell viability as shown by a gene disruption experiment. Epitope-tagging of the TFC3 gene product and DNA binding experiments are consistent with the presence of one copy of tau 138 in TFIIIC-DNA complexes.

Bibliography

Lefebvre, O., Carles, C., Conesa, C., Swanson, R. N., Bouet, F., Riva, M., & Sentenac, A. (1992). TFC3: gene encoding the B-block binding subunit of the yeast transcription factor IIIC. Proceedings of the National Academy of Sciences, 89(21), 10512â10516.

Authors 7

O Lefebvre (first)
C Carles (additional)
C Conesa (additional)
R N Swanson (additional)
F Bouet (additional)
M Riva (additional)
A Sentenac (additional)

References 0 Referenced 45

None

Dates

Type	When
Created	19 years, 2 months ago (May 31, 2006, 8:11 a.m.)
Deposited	3 years, 4 months ago (April 13, 2022, 1:50 p.m.)
Indexed	11 months, 3 weeks ago (Aug. 31, 2024, 10:05 a.m.)
Issued	32 years, 9 months ago (Nov. 1, 1992)
Published	32 years, 9 months ago (Nov. 1, 1992)
Published Online	32 years, 9 months ago (Nov. 1, 1992)
Published Print	32 years, 9 months ago (Nov. 1, 1992)

Funders 0

None

BibTeX

@article{Lefebvre_1992, title={TFC3: gene encoding the B-block binding subunit of the yeast transcription factor IIIC.}, volume={89}, ISSN={1091-6490}, url={http://dx.doi.org/10.1073/pnas.89.21.10512}, DOI={10.1073/pnas.89.21.10512}, number={21}, journal={Proceedings of the National Academy of Sciences}, publisher={Proceedings of the National Academy of Sciences}, author={Lefebvre, O and Carles, C and Conesa, C and Swanson, R N and Bouet, F and Riva, M and Sentenac, A}, year={1992}, month=nov, pages={10512–10516} }

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