DOI: 10.1073/pnas.88.14.6244. The subtypes of the mouse inositol 1,4,5-trisphosphate receptor are expressed in a tissue-specific and developmentally specific manner.

The subtypes of the mouse inositol 1,4,5-trisphosphate receptor are expressed in a tissue-specific and developmentally specific manner.

10.1073/pnas.88.14.6244

Crossref journal-article

Proceedings of the National Academy of Sciences

Proceedings of the National Academy of Sciences (341)

Abstract

Additional subtypes of the inositol 1,4,5-trisphosphate (InsP3) receptor are expressed in a tissue-specific and developmentally specific manner. They differ from the InsP3 receptor structure previously reported in two small variably spliced segments. One segment (SI) is located within the InsP3 binding site, whereas another segment (SII) is located near putative sites for phosphorylation and ATP binding to modulate InsP3 action on Ca2+ flux. Therefore, we speculate that selective use of InsP3 receptor subtypes permits a tissue-specific and developmentally specific expression of functionally distinct channels.

Bibliography

Nakagawa, T., Okano, H., Furuichi, T., Aruga, J., & Mikoshiba, K. (1991). The subtypes of the mouse inositol 1,4,5-trisphosphate receptor are expressed in a tissue-specific and developmentally specific manner. Proceedings of the National Academy of Sciences, 88(14), 6244â6248.

Authors 5

T Nakagawa (first)
H Okano (additional)
T Furuichi (additional)
J Aruga (additional)
K Mikoshiba (additional)

References 0 Referenced 157

None

Dates

Type	When
Created	19 years, 3 months ago (May 31, 2006, 7:41 a.m.)
Deposited	3 years, 4 months ago (April 13, 2022, 1:19 p.m.)
Indexed	11 months, 4 weeks ago (Sept. 6, 2024, 7:52 p.m.)
Issued	34 years, 1 month ago (July 15, 1991)
Published	34 years, 1 month ago (July 15, 1991)
Published Online	34 years, 1 month ago (July 15, 1991)
Published Print	34 years, 1 month ago (July 15, 1991)

Funders 0

None

BibTeX

@article{Nakagawa_1991, title={The subtypes of the mouse inositol 1,4,5-trisphosphate receptor are expressed in a tissue-specific and developmentally specific manner.}, volume={88}, ISSN={1091-6490}, url={http://dx.doi.org/10.1073/pnas.88.14.6244}, DOI={10.1073/pnas.88.14.6244}, number={14}, journal={Proceedings of the National Academy of Sciences}, publisher={Proceedings of the National Academy of Sciences}, author={Nakagawa, T and Okano, H and Furuichi, T and Aruga, J and Mikoshiba, K}, year={1991}, month=jul, pages={6244–6248} }

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