DOI: 10.1073/pnas.87.21.8355. Changes in the stability of specific mRNA species in response to growth stage in Bacillus subtilis.

Changes in the stability of specific mRNA species in response to growth stage in Bacillus subtilis.

10.1073/pnas.87.21.8355

Crossref journal-article

Proceedings of the National Academy of Sciences

Proceedings of the National Academy of Sciences (341)

Abstract

In this study we compared the cellular concentrations and stability of the mRNA transcribed from the aprE (subtilisin) gene (a gene preferentially expressed in stationary growth phase) with those of a vegetative mRNA, succinate dehydrogenase (SDH) mRNA. The subtilisin transcript was shown to be at least 3 times more stable in early stationary phase than it is 2 hr further into stationary phase. When cells were shifted from maximum expression of the subtilisin transcript in stationary phase to physiological conditions, which allowed for the resumption of vegetative growth, the cellular concentration of the subtilisin mRNA decreased rapidly. We conclude that mRNA degradation is one of the means by which the cellular concentrations of the SDH and subtilisin transcripts are adjusted in response to growth stage.

Bibliography

Resnekov, O., Rutberg, L., & von Gabain, A. (1990). Changes in the stability of specific mRNA species in response to growth stage in Bacillus subtilis. Proceedings of the National Academy of Sciences, 87(21), 8355â8359.

Authors 3

O Resnekov (first)
L Rutberg (additional)
A von Gabain (additional)

References 0 Referenced 41

None

Dates

Type	When
Created	19 years, 3 months ago (May 31, 2006, 7:30 a.m.)
Deposited	3 years, 4 months ago (April 13, 2022, 1:14 p.m.)
Indexed	1 year, 3 months ago (May 17, 2024, 8:55 p.m.)
Issued	34 years, 9 months ago (Nov. 1, 1990)
Published	34 years, 9 months ago (Nov. 1, 1990)
Published Online	34 years, 9 months ago (Nov. 1, 1990)
Published Print	34 years, 9 months ago (Nov. 1, 1990)

Funders 0

None

BibTeX

@article{Resnekov_1990, title={Changes in the stability of specific mRNA species in response to growth stage in Bacillus subtilis.}, volume={87}, ISSN={1091-6490}, url={http://dx.doi.org/10.1073/pnas.87.21.8355}, DOI={10.1073/pnas.87.21.8355}, number={21}, journal={Proceedings of the National Academy of Sciences}, publisher={Proceedings of the National Academy of Sciences}, author={Resnekov, O and Rutberg, L and von Gabain, A}, year={1990}, month=nov, pages={8355–8359} }

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