DOI: 10.1073/pnas.86.19.7465. Z-DNA-forming sequences are spontaneous deletion hot spots.

Z-DNA-forming sequences are spontaneous deletion hot spots.

10.1073/pnas.86.19.7465

Crossref journal-article

Proceedings of the National Academy of Sciences

Proceedings of the National Academy of Sciences (341)

Abstract

Z-DNA-forming sequences are shown to elicit a biological response in Escherichia coli. Plasmids containing sequences capable of adopting the Z conformation (GC and CA/GT) are shown to be hot spots for spontaneous deletions. All the deletions involve an even number of base pairs. The distribution of the deletion events shows that the process ends when the Z-DNA-forming sequence has been reduced to a size no longer capable of adopting the Z conformation at natural superhelical density.

Bibliography

Freund, A. M., Bichara, M., & Fuchs, R. P. (1989). Z-DNA-forming sequences are spontaneous deletion hot spots. Proceedings of the National Academy of Sciences, 86(19), 7465â7469.

Authors 3

A M Freund (first)
M Bichara (additional)
R P Fuchs (additional)

References 0 Referenced 52

None

Dates

Type	When
Created	19 years, 3 months ago (May 31, 2006, 7:03 a.m.)
Deposited	3 years, 4 months ago (April 13, 2022, 12:40 p.m.)
Indexed	1 year, 8 months ago (Dec. 6, 2023, 1:45 p.m.)
Issued	35 years, 11 months ago (Oct. 1, 1989)
Published	35 years, 11 months ago (Oct. 1, 1989)
Published Online	35 years, 11 months ago (Oct. 1, 1989)
Published Print	35 years, 11 months ago (Oct. 1, 1989)

Funders 0

None

BibTeX

@article{Freund_1989, title={Z-DNA-forming sequences are spontaneous deletion hot spots.}, volume={86}, ISSN={1091-6490}, url={http://dx.doi.org/10.1073/pnas.86.19.7465}, DOI={10.1073/pnas.86.19.7465}, number={19}, journal={Proceedings of the National Academy of Sciences}, publisher={Proceedings of the National Academy of Sciences}, author={Freund, A M and Bichara, M and Fuchs, R P}, year={1989}, month=oct, pages={7465–7469} }

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