DOI: 10.1073/pnas.83.23.8987. Temporal comparisons in bacterial chemotaxis.

Temporal comparisons in bacterial chemotaxis.

10.1073/pnas.83.23.8987

Crossref journal-article

Proceedings of the National Academy of Sciences

Proceedings of the National Academy of Sciences (341)

Abstract

Responses of tethered cells of Escherichia coli to impulse, step, exponential-ramp or exponentiated sine-wave stimuli are internally consistent, provided that allowance is made for the nonlinear effect of thresholds. This result confirms that wild-type cells exposed to stimuli in the physiological range make short-term temporal comparisons extending 4 sec into the past: the past second is given a positive weighting, the previous 3 sec are given a negative weighting, and the cells respond to the difference. cheRcheB mutants (defective in methylation and demethylation) weight the past second in a manner similar to the wild type, but they do not make short-term temporal comparisons. When exposed to small steps delivered iontophoretically, they fail to adapt over periods of up to 12 sec; when exposed to longer steps in a flow cell, they partially adapt, but with a decay time of greater than 30 sec. cheZ mutants use a weighting that extends at least 40 sec into the past. The gain of the chemotactic system is large: the change in occupancy of one receptor molecule produces a significant response.

Authors 3

J E Segall (first)
S M Block (additional)
H C Berg (additional)

References 0 Referenced 393

None

Dates

Type	When
Created	19 years, 2 months ago (May 31, 2006, 6:10 a.m.)
Deposited	3 years, 4 months ago (April 13, 2022, 12:30 p.m.)
Indexed	2 weeks, 3 days ago (Aug. 12, 2025, 6:01 p.m.)
Issued	38 years, 8 months ago (Dec. 1, 1986)
Published	38 years, 8 months ago (Dec. 1, 1986)
Published Online	38 years, 8 months ago (Dec. 1, 1986)
Published Print	38 years, 8 months ago (Dec. 1, 1986)

Funders 0

None

BibTeX

@article{Segall_1986, title={Temporal comparisons in bacterial chemotaxis.}, volume={83}, ISSN={1091-6490}, url={http://dx.doi.org/10.1073/pnas.83.23.8987}, DOI={10.1073/pnas.83.23.8987}, number={23}, journal={Proceedings of the National Academy of Sciences}, publisher={Proceedings of the National Academy of Sciences}, author={Segall, J E and Block, S M and Berg, H C}, year={1986}, month=dec, pages={8987–8991} }

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